STRINGSTRING
cdh13 cdh13 cdh6 cdh6 cdh31 cdh31 ctnna1 ctnna1 cdh4 cdh4 cdh1 cdh1 cdh30 cdh30 cdh28 cdh28 CDH18 CDH18 LOC100534755 LOC100534755 ctnnb1 ctnnb1 LOC100536716 LOC100536716 apc apc cdh18a cdh18a cdh15 cdh15 apc2 apc2 jupb jupb ctnnb2 ctnnb2 F1R963_DANRE F1R963_DANRE cdh10a cdh10a cdh27 cdh27 LOC100329245 LOC100329245 cdh7a cdh7a jupa jupa cdh11 cdh11 cdh2 cdh2 cdh5 cdh5 cdh26.1 cdh26.1 LOC101882238 LOC101882238 ctnna2 ctnna2 cdh12a cdh12a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdh13Cadherin 13, H-cadherin (heart). (661 aa)
cdh6Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
cdh31Cadherin 31; Cadherins are calcium-dependent cell adhesion proteins. (842 aa)
ctnna1Catenin (cadherin-associated protein), alpha 1. (907 aa)
cdh4Cadherin 4, type 1, R-cadherin (retinal); Cadherins are calcium-dependent cell adhesion proteins. (931 aa)
cdh1Cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. (877 aa)
cdh30Cadherin 30. (740 aa)
cdh28Cadherin 28. (795 aa)
CDH18Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. (816 aa)
LOC100534755Uncharacterized protein. (616 aa)
ctnnb1Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] (789 aa)
LOC100536716Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
apcAPC regulator of WNT-signaling pathway. (2754 aa)
cdh18aCadherin 18, type 2a. (108 aa)
cdh15Cadherin 15, type 1, M-cadherin (myotubule); Cadherins are calcium-dependent cell adhesion proteins. (792 aa)
apc2APC regulator of WNT-signaling pathway 2. (2105 aa)
jupbJunction plakoglobin b. (726 aa)
ctnnb2Catenin, beta 2. (778 aa)
F1R963_DANRESi:dkey-30c15.12; Cadherins are calcium-dependent cell adhesion proteins. (737 aa)
cdh10aCadherin 10, type 2a (T2-cadherin); Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
cdh27Cadherin 27. (813 aa)
LOC100329245Cadherin 7b; Cadherins are calcium-dependent cell adhesion proteins. (668 aa)
cdh7aCdh7 protein; Cadherins are calcium-dependent cell adhesion proteins. (787 aa)
jupaJunction plakoglobin a. (729 aa)
cdh11Cadherin 11, type 2, OB-cadherin (osteoblast); Cadherins are calcium-dependent cell adhesion proteins. (800 aa)
cdh2Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion (By similarity). Cadherins contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development. Required for normal neural tube morphogenesis. Required to allow mid- and hindbrain neurons to reach and maintain their appropriate positions within the neural tube by restricting neuronal motility within the embryonic mid- and hindbrain. (893 aa)
cdh5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (767 aa)
cdh26.1Cadherin 26, tandem duplicate 1. (873 aa)
LOC101882238Cadherin 26, tandem duplicate 2. (852 aa)
ctnna2Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. (865 aa)
cdh12aCadherin 12, type 2a (N-cadherin 2); Cadherins are calcium-dependent cell adhesion proteins. (800 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.