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bco2l bco2l hpda hpda rpe65a rpe65a zgc:152891 zgc:152891 adi1 adi1 tdo2b tdo2b ethe1 ethe1 ido1 ido1 bco2b bco2b adoa adoa eipr1 eipr1 hpdb hpdb rpe65b rpe65b rpe65c rpe65c alox5a alox5a hgd hgd haao haao alox12 alox12 alox5b.3 alox5b.3 tdo2a tdo2a E9QGC1_DANRE E9QGC1_DANRE bco2a bco2a pir pir adob adob alox5b.2 alox5b.2 alox5b.1 alox5b.1 bco1l bco1l hpdl hpdl bco1 bco1 HPDL HPDL cdo1 cdo1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bco2lBeta-carotene 15, 15-dioxygenase 2,-like. (549 aa)
hpda4-hydroxyphenylpyruvate dioxygenase; Key enzyme in the degradation of tyrosine; Belongs to the 4HPPD family. (397 aa)
rpe65aRetinoid isomerohydrolase; Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). (531 aa)
zgc:152891Zgc:152891. (663 aa)
adi11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (181 aa)
tdo2bTryptophan 2,3-dioxygenase B; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (407 aa)
ethe1ETHE1 persulfide dioxygenase. (279 aa)
ido1Indoleamine 2,3-dioxygenase 1. (435 aa)
bco2bBeta-carotene oxygenase 2a. (555 aa)
adoa2-aminoethanethiol (cysteamine) dioxygenase a. (248 aa)
eipr1EARP-interacting protein homolog; Belongs to the WD repeat EIPR1 family. (391 aa)
hpdb4-hydroxyphenylpyruvate dioxygenase. (393 aa)
rpe65bAll-trans-retinyl ester 13-cis isomerohydrolase; Specifically generates 13-cis retinol, a stereoisomeric form of retinoic acid. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). (532 aa)
rpe65cRetinal Mueller cells isomerohydrolase; Catalyzes both 11-cis retinol and 13-cis retinol, 2 stereoisomeric forms of retinoic acid from all-trans-retinyl ester. Acts as an alternative isomerohydrolase in retinal Mueller cells by catalyzing formation of 11-cis retinol, to meet the high demand for the chromophore by cones. Capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (By similarity). (532 aa)
alox5aArachidonate 5-lipoxygenase a. (674 aa)
hgdHomogentisate 1,2-dioxygenase. (443 aa)
haao3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (287 aa)
alox12Arachidonate 12-lipoxygenase. (670 aa)
alox5b.3Arachidonate 5-lipoxygenase b, tandem duplicate 3. (676 aa)
tdo2aTryptophan 2,3-dioxygenase A; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
E9QGC1_DANRESi:dkey-17e16.9. (669 aa)
bco2aBeta-carotene oxygenase 2a. (572 aa)
pirPirin; Belongs to the pirin family. (290 aa)
adob2-aminoethanethiol (cysteamine) dioxygenase b. (254 aa)
alox5b.2Arachidonate 5-lipoxygenase b, tandem duplicate 2. (676 aa)
alox5b.1Arachidonate 5-lipoxygenase b, tandem duplicate 1. (697 aa)
bco1lBeta-carotene oxygenase 1,-like. (535 aa)
hpdl4-hydroxyphenylpyruvate dioxygenase. (420 aa)
bco1Beta-carotene oxygenase 1. (565 aa)
HPDL4-hydroxyphenylpyruvate dioxygenase. (420 aa)
cdo1Cysteine dioxygenase type 1; Belongs to the cysteine dioxygenase family. (203 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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