STRINGSTRING
drd4-rs drd4-rs uvrag uvrag cyba cyba wipf3 wipf3 qkib qkib shank2a shank2a adam10a adam10a inppl1b inppl1b vaspa vaspa wipf1a wipf1a qkia qkia sh3bp5a sh3bp5a drd4a drd4a mvb12a mvb12a prrt2 prrt2 sh3d21 sh3d21 elmo2 elmo2 ostf1 ostf1 ENSDARP00000133413 ENSDARP00000133413 evlb evlb elmo1 elmo1 sh3bp5b sh3bp5b adam10b adam10b errfi1a errfi1a shank1 shank1 X1WBN8_DANRE X1WBN8_DANRE afap1 afap1 adam17b adam17b sh3bgr sh3bgr wipf1b wipf1b fut8a fut8a synj1 synj1 rad9b rad9b sh3kbp1 sh3kbp1 dennd1a dennd1a shank2b shank2b znf106a znf106a shank3b shank3b abi1a abi1a sh3bp2 sh3bp2 E9QGJ0_DANRE E9QGJ0_DANRE afap1l1a afap1l1a nitr1i nitr1i fut8b fut8b inpp5d inpp5d nitr1a nitr1a rufy1 rufy1 cblc cblc khdrbs1b khdrbs1b cd2ap cd2ap afap1l2 afap1l2 nitr1f nitr1f cttnbp2 cttnbp2 vaspb vaspb nitr1d nitr1d abi3b abi3b shank3a shank3a abi1b abi1b rufy2 rufy2 abi3a abi3a sh3bgrl sh3bgrl abi2a abi2a zgc:66443 zgc:66443 afap1l1b afap1l1b pttg1 pttg1 khdrbs1a khdrbs1a abi2b abi2b adam17a adam17a nitr1n nitr1n elmo3 elmo3 rad9a rad9a sh3bgrl2 sh3bgrl2 drd4b drd4b evla evla ncf1 ncf1 zgc:92429 zgc:92429 casp9 casp9 enkur enkur cblb cblb cbl cbl qki2 qki2 enah enah
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
drd4-rsDopamine receptor D4-related sequence; Belongs to the G-protein coupled receptor 1 family. (418 aa)
uvragUV radiation resistance-associated gene. (664 aa)
cybaCytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (185 aa)
wipf3Sb:cb649. (401 aa)
qkibProtein quaking-B. (347 aa)
shank2aSH3 and multiple ankyrin repeat domains 2a. (1306 aa)
adam10aADAM metallopeptidase domain 10a. (763 aa)
inppl1bPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...] (1226 aa)
vaspaVasodilator-stimulated phosphoprotein a. (412 aa)
wipf1aWAS/WASL-interacting protein family, member 1a. (520 aa)
qkiaProtein quaking-A; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of some pre-mRNA. Acts as a translational repressor (By similarity). (383 aa)
sh3bp5aSH3-domain-binding protein 5a (BTK-associated). (444 aa)
drd4aDopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (380 aa)
mvb12aMultivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (By similarity). (89 aa)
prrt2Proline-rich transmembrane protein 2. (226 aa)
sh3d21SH3 domain-containing 21. (425 aa)
elmo2Engulfment and cell motility 2. (675 aa)
ostf1Osteoclast-stimulating factor 1; Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. (214 aa)
ENSDARP00000133413Si:dkey-220o5.5. (286 aa)
evlbEnah/Vasp-like b. (359 aa)
elmo1Engulfment and Cell motility 1 (Ced-12 homolog, C. elegans). (726 aa)
sh3bp5bSH3-domain-binding protein 5b (BTK-associated). (446 aa)
adam10bADAM metallopeptidase domain 10b. (600 aa)
errfi1aERBB receptor feedback inhibitor 1a. (447 aa)
shank1SH3 and multiple ankyrin repeat domains 1. (852 aa)
X1WBN8_DANRESi:dkey-56f14.7. (254 aa)
afap1Actin filament-associated protein 1. (806 aa)
adam17bADAM metallopeptidase domain 17b. (843 aa)
sh3bgrSH3 domain-binding glutamate-rich protein. (185 aa)
wipf1bWAS/WASL-interacting protein family, member 1b. (485 aa)
fut8aAlpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (581 aa)
synj1Synaptojanin 1. (1308 aa)
rad9bCell cycle checkpoint control protein; Belongs to the rad9 family. (402 aa)
sh3kbp1SH3-domain kinase-binding protein 1. (669 aa)
dennd1aDENN/MADD domain-containing 1A. (511 aa)
shank2bSH3 and multiple ankyrin repeat domains 2b. (1800 aa)
znf106aZinc finger protein 106a. (1636 aa)
shank3bSH3 and multiple ankyrin repeat domains 3b. (1631 aa)
abi1aAbl-interactor 1a. (483 aa)
sh3bp2SH3-domain-binding protein 2. (494 aa)
E9QGJ0_DANRESi:dkey-71d15.2. (184 aa)
afap1l1aActin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation. (747 aa)
nitr1iNovel immune-type receptor 1i. (328 aa)
fut8bAlpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (579 aa)
inpp5dInositol polyphosphate-5-phosphatase D. (1082 aa)
nitr1aNovel immune-type receptor 1a, allele 3. (329 aa)
rufy1RUN and FYVE domain-containing 1. (697 aa)
cblcCbl proto-oncogene C, E3 ubiquitin protein ligase. (502 aa)
khdrbs1bKH domain-containing, RNA-binding, signal transduction-associated 1b. (352 aa)
cd2apCD2-associated protein. (657 aa)
afap1l2Actin filament-associated protein 1-like 2. (859 aa)
nitr1fNovel immune-type receptor 1f, allele 1. (327 aa)
cttnbp2Cortactin-binding protein 2. (1573 aa)
vaspbVasodilator-stimulated phosphoprotein b. (445 aa)
nitr1dNovel immune-type receptor 1d, allele 5. (324 aa)
abi3bABI family, member 3b. (415 aa)
shank3aSH3 and multiple ankyrin repeat domains 3a. (1509 aa)
abi1bAbl-interactor 1b. (502 aa)
rufy2RUN and FYVE domain-containing 2. (698 aa)
abi3aABI family, member 3a. (454 aa)
sh3bgrlSH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family. (115 aa)
abi2aAbl-interactor 2a. (394 aa)
zgc:66443Zgc:66443. (327 aa)
afap1l1bActin filament-associated protein 1-like 1b. (754 aa)
pttg1PTTG1 regulator of sister chromatid separation, securin. (182 aa)
khdrbs1aKH domain-containing, RNA-binding, signal transduction-associated 1a. (370 aa)
abi2bAbl-interactor 2b. (461 aa)
adam17aADAM metallopeptidase domain 17a. (842 aa)
nitr1nNovel immune-type receptor 1b. (330 aa)
elmo3Engulfment and cell motility 3. (715 aa)
rad9aCell cycle checkpoint control protein; Belongs to the rad9 family. (381 aa)
sh3bgrl2SH3 domain-binding glutamic acid-rich-like protein 2. (105 aa)
drd4bDopamine D4c receptor; Belongs to the G-protein coupled receptor 1 family. (382 aa)
evlaEnah/Vasp-like a. (387 aa)
ncf1Neutrophil cytosolic factor 1. (410 aa)
zgc:92429Zgc:92429. (387 aa)
casp9Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (436 aa)
enkurEnkurin, TRPC channel-interacting protein. (259 aa)
cblbCbl proto-oncogene B, E3 ubiquitin protein ligase. (939 aa)
cblCbl proto-oncogene, E3 ubiquitin protein ligase. (913 aa)
qki2Protein quaking-B; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of some pre-mRNA. Acts as a translational repressor (By similarity). (319 aa)
enahENAH actin regulator. (804 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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