STRINGSTRING
chek1 chek1 csnk2a1 csnk2a1 gsk3ab gsk3ab pdpk1b pdpk1b zgc:86598 zgc:86598 prkcba prkcba csnk2a2a csnk2a2a gsk3ba gsk3ba dyrk1b dyrk1b prkcbb prkcbb tgfbr2b tgfbr2b cdc42bpab cdc42bpab unm_sa1261 unm_sa1261 csnk2a2b csnk2a2b oxsr1a oxsr1a cdc42bpb cdc42bpb prkdc prkdc dyrk1ab dyrk1ab stk11 stk11 gsk3bb gsk3bb F1QAH4_DANRE F1QAH4_DANRE cdk5 cdk5 tgfbr2a tgfbr2a hipk2 hipk2 E7F551_DANRE E7F551_DANRE rock2b-2 rock2b-2 dyrk1aa dyrk1aa pdpk1a pdpk1a dyrk4 dyrk4 nlk1 nlk1 Dmpk Dmpk mtor mtor dyrk3 dyrk3 nlk2 nlk2 stk39 stk39 gsk3aa gsk3aa oxsr1b oxsr1b hipk3a hipk3a E9QGL6_DANRE E9QGL6_DANRE hipk3b hipk3b bcl2a bcl2a rock2a rock2a dyrk2 dyrk2 prkcg prkcg bcl2b bcl2b ENSDARP00000130960 ENSDARP00000130960 csnk2a4 csnk2a4 cdc42bpaa cdc42bpaa bsk146 bsk146 rock2b rock2b prkcab prkcab ENSDARP00000140512 ENSDARP00000140512 rock1 rock1 rock2bl rock2bl ENSDARP00000148508 ENSDARP00000148508 ENSDARP00000149604 ENSDARP00000149604 ENSDARP00000151824 ENSDARP00000151824 prkcaa prkcaa hipk1a hipk1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chek1CHK1 checkpoint homolog (S. pombe); Belongs to the protein kinase superfamily. (410 aa)
csnk2a1Casein kinase 2, alpha 1 polypeptide; Belongs to the protein kinase superfamily. (395 aa)
gsk3abGlycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
pdpk1b3-phosphoinositide-dependent protein kinase 1b. (537 aa)
zgc:86598Zgc:86598; Belongs to the protein kinase superfamily. (393 aa)
prkcbaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
csnk2a2aCasein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (348 aa)
gsk3baGlycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
dyrk1bDual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1B. (751 aa)
prkcbbProtein kinase C beta type; Calcium-activated and phospholipid-dependent serine/threonine-protein kinase involved in various processes such as regulation of the B-cell receptor (BCR) signalosome, apoptosis and transcription regulation. Plays a key role in B-cell activation and function by regulating BCR-induced NF-kappa-B activation and B-cell survival. Required for recruitment and activation of the IKK kinase to lipid rafts and mediates phosphorylation of card11/carma1, leading to activate the NF-kappa-B signaling. Involved in apoptosis following oxidative damage: in case of oxidative [...] (670 aa)
tgfbr2bTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (556 aa)
cdc42bpabNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1716 aa)
unm_sa1261Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (409 aa)
csnk2a2bCasein kinase 2, alpha prime polypeptide b; Belongs to the protein kinase superfamily. (350 aa)
oxsr1aOxidative stress-responsive kinase 1a. (515 aa)
cdc42bpbCDC42-binding protein kinase beta (DMPK-like); Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1708 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4119 aa)
dyrk1abDual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A, b. (727 aa)
stk11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
gsk3bbGlycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (419 aa)
F1QAH4_DANRETGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (590 aa)
cdk5Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
tgfbr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (645 aa)
hipk2Homeodomain-interacting protein kinase 2. (1220 aa)
E7F551_DANRESi:ch211-160o17.4. (1081 aa)
rock2b-2Rho-associated, coiled-coil-containing protein kinase 2b. (383 aa)
dyrk1aaDual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A, a. (737 aa)
pdpk1a3-phosphoinositide-dependent protein kinase 1a. (536 aa)
dyrk4Dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 4. (634 aa)
nlk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (475 aa)
DmpkUncharacterized protein; Belongs to the protein kinase superfamily. (419 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2563 aa)
dyrk3Dual-specificity tyrosine phosphorylation-regulated kinase 3. (582 aa)
nlk2Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (533 aa)
stk39Serine threonine kinase 39. (529 aa)
gsk3aaGlycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (462 aa)
oxsr1bOxidative stress-responsive kinase 1b. (520 aa)
hipk3aHomeodomain-interacting protein kinase 3a. (1229 aa)
E9QGL6_DANRESi:dkeyp-26a9.2. (1092 aa)
hipk3bHomeodomain-interacting protein kinase 3b. (1261 aa)
bcl2aB-cell leukemia/lymphoma 2. (228 aa)
rock2aRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1375 aa)
dyrk2Dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 2. (587 aa)
prkcgProtein kinase C, gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (654 aa)
bcl2bBCL2 apoptosis regulator b. (209 aa)
ENSDARP00000130960Si:dkey-65b13.9. (181 aa)
csnk2a4Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (389 aa)
cdc42bpaaNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1697 aa)
bsk146Serine/threonine-protein kinase SBK1; May be involved in the control of neuronal proliferation or migration in the brain of embryos; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (385 aa)
rock2bRho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1401 aa)
prkcabProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (635 aa)
ENSDARP00000140512Si:dkey-238n5.3. (99 aa)
rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1359 aa)
rock2blRho-associated, coiled-coil-containing protein kinase 2b,-like. (181 aa)
ENSDARP00000148508ecTbetaR2 domain-containing protein. (382 aa)
ENSDARP00000149604Uncharacterized protein. (277 aa)
ENSDARP00000151824AGC-kinase C-terminal domain-containing protein. (58 aa)
prkcaaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
hipk1aHomeodomain-interacting protein kinase 1a. (1093 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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