STRINGSTRING
Kndc1 Kndc1 LOC100331987 LOC100331987 ENSDARP00000139496 ENSDARP00000139496 agbl1 agbl1 sez6a sez6a coq8b coq8b hspa5 hspa5 agtpbp1 agtpbp1 sez6b sez6b ttll1 ttll1 snx14 snx14 whrnb whrnb whrna whrna sez6l2 sez6l2 clp1 clp1 kif14 kif14 klhl5 klhl5 cdk5 cdk5 mdka mdka naglu naglu ttc21b ttc21b serpine2 serpine2 uqcrq uqcrq wdr73 wdr73 lhx1b lhx1b lhx1a lhx1a mdkb mdkb smo smo rbm7 rbm7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Kndc1Uncharacterized protein. (118 aa)
LOC100331987Seizure-related 6 homolog (mouse)-like. (937 aa)
ENSDARP00000139496Si:ch211-160f23.7. (225 aa)
agbl1ATP/GTP-binding protein-like 1. (1028 aa)
sez6aSeizure-related 6 homolog a. (970 aa)
coq8bAtypical kinase COQ8B, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration. (624 aa)
hspa5Immunoglobulin binding protein; Belongs to the heat shock protein 70 family. (650 aa)
agtpbp1Cytosolic carboxypeptidase 1; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate. (1153 aa)
sez6bSeizure-related 6 homolog b. (1027 aa)
ttll1Tubulin tyrosine ligase-like family, member 1. (423 aa)
snx14Sorting nexin-14; Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking (By similarity). Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes. Binds phosphatidylinositol 3,5- bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes. Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)) (By similarity). (934 aa)
whrnbWhirlin b. (946 aa)
whrnaWhirlin a. (939 aa)
sez6l2Seizure-related 6 homolog (mouse)-like 2. (898 aa)
clp1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Plays a role in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex: phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phospho [...] (443 aa)
kif14Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1506 aa)
klhl5Kelch-like family member 5. (769 aa)
cdk5Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
mdkaMidkine-related growth factor Mdk1. (146 aa)
nagluN-acetylglucosaminidase, alpha. (757 aa)
ttc21bTetratricopeptide repeat domain 21B. (1321 aa)
serpine2Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (395 aa)
uqcrqUbiquinol-cytochrome c reductase, complex III subunit VII. (82 aa)
wdr73WD repeat-containing protein 73; May play a role in the regulation of microtubule organization and dynamics; Belongs to the WD repeat WDR73 family. (376 aa)
lhx1bLIM class homeodomain protein. (402 aa)
lhx1aLIM/homeobox protein Lhx1; Seems to play a role in dorsal axis formation. (405 aa)
mdkbMidkine-related growth factor Mdk2. (147 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa)
rbm7RNA-binding protein 7; RNA-binding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. Binds preferentially polyuridine sequences and associates with newly synthesized RNAs, including pre- mRNAs and short-lived exosome substrates such as promoter upstream transcripts (PROMPTs), enhancer RNAs (eRNAs), and 3'-extended products from small nuclear RNAs (snRNAs). (252 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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