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| | srpk1a | SRSF protein kinase 1a. (634 aa) |
| | yju2 | Splicing factor YJU2; Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates (By similarity). May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex ; Belongs to the CWC16 family. YJU2 subfamily. (345 aa) |
| | shq1 | Protein SHQ1 homolog; Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs); Belongs to the SHQ1 family. (586 aa) |
| | mcts1 | Malignant T-cell-amplified sequence 1; Plays a role as translation enhancer and involved in cell cycle regulation. (181 aa) |
| | lsm4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (143 aa) |
| | snu13b | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa) |
| | celf3a | CUGBP Elav-like family member 3; RNA-binding protein that may be involved in the regulation of pre-mRNA alternative splicing; Belongs to the CELF/BRUNOL family. (452 aa) |
| | celf1 | CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. May be involved in mRNA translation activation and stability (By similarity). Involved in the regulation of muscle-specific splicing of alpha actinin pre-mRNAs via the binding to the UR-repeat element (URE) at the branch point of the non-muscle (NM) exon; Belongs to the CELF/BRUNOL family. (534 aa) |
| | srpk1b | SRSF protein kinase 1b. (658 aa) |
| | snrpe | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (92 aa) |
| | znhit2 | Zinc finger, HIT-type-containing 2. (522 aa) |
| | prkdc | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4119 aa) |
| | eif3hb | Eukaryotic translation initiation factor 3 subunit H-B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (333 aa) |
| | gemin8 | Gem (nuclear organelle)-associated protein 8. (217 aa) |
| | ptges3a | Prostaglandin E synthase 3a (cytosolic). (159 aa) |
| | pih1d1 | PIH1 domain-containing protein 1; Involved in the assembly of C/D box small nucleolar ribonucleoprotein (snoRNP) particles (By similarity). Recruits the SWI/SNF complex to the core promoter of rRNA genes and enhances pre- rRNA transcription (By similarity). Mediates interaction of TELO2 with the R2TP complex which is necessary for the stability of MTOR and SMG1 (By similarity). Positively regulates the assembly and activity of the mTORC1 complex (By similarity); Belongs to the PIH1 family. (287 aa) |
| | snrpd2 | Small nuclear ribonucleoprotein Sm D2. (118 aa) |
| | khdc4 | KH homology domain-containing protein 4; RNA-binding protein involved in pre-mRNA splicing. Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome. Involved in regulating splice site selection. Binds preferentially RNA with A/C rich sequences and poly-C stretches. (570 aa) |
| | gemin7 | Gem (nuclear organelle)-associated protein 7. (125 aa) |
| | gemin4 | Gem (nuclear organelle)-associated protein 4. (1057 aa) |
| | usp39 | Ubiquitin-specific peptidase 39. (497 aa) |
| | rps5 | Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa) |
| | celf2 | CUGBP Elav-like family member 2; RNA-binding protein implicated in the regulation of several post-transcriptional events. May be involved in pre-mRNA alternative splicing, mRNA translation repression and stability (By similarity). (493 aa) |
| | sfswap | Splicing factor SWAP. (958 aa) |
| | puf60a | Poly-U-binding-splicing factor a. (519 aa) |
| | snrpc | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (159 aa) |
| | xab2 | Similar to Xab2 protein. (851 aa) |
| | eif2d | Eukaryotic translation initiation factor 2D. (590 aa) |
| | eif4bb | Eukaryotic translation initiation factor 4Bb. (569 aa) |
| | rpl23a | Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family. (155 aa) |
| | celf3b | Cugbp, Elav-like family member 3b. (442 aa) |
| | rpl5a | Ribosomal protein L5a. (297 aa) |
| | rpl38 | Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa) |
| | sart3 | Squamous cell carcinoma antigen recognized by T-cells 3; U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation. May also function as a substrate targeting factor for deubiquitinases and mediate the deubiquitination of components of the spliceosome and histones (By similarity). (951 aa) |
| | sf3a2 | Splicing factor 3a, subunit 2. (278 aa) |
| | mrto4 | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (242 aa) |
| | rps28 | 40S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family. (69 aa) |
| | adar | Adenosine deaminase RNA-specific. (1381 aa) |
| | eif4h | Eukaryotic translation initiation factor 4h. (256 aa) |
| | dhx9 | DEAH (Asp-Glu-Ala-His) box helicase 9. (1271 aa) |
| | prpf31 | U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. (508 aa) |
| | rpl10 | 60S ribosomal protein L10; Component of the large ribosomal subunit (Probable). Plays a role in the formation of actively translating ribosomes. Plays a role in the embryonic brain development. (215 aa) |
| | prpf8 | Pre-mRNA-processing factor 8. (2342 aa) |
| | eif3d | Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (552 aa) |
| | snrpd3 | Small nuclear ribonucleoprotein Sm D3. (127 aa) |
| | eif3c | Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (926 aa) |
| | gemin6 | Gem (nuclear organelle)-associated protein 6. (137 aa) |
| | trnau1apa | tRNA selenocysteine 1-associated protein 1; Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Belongs to the RRM TRSPAP family. (314 aa) |
| | psip1a | PC4 and SFRS1-interacting protein 1a. (413 aa) |
| | sf3a3 | Splicing factor 3a, subunit 3. (501 aa) |
| | rps27l | 40S ribosomal protein S27. (84 aa) |
| | prpf39 | Pre-mRNA-processing factor 39; Involved in pre-mRNA splicing; Belongs to the PRP39 family. (752 aa) |
| | nufip1 | Nuclear FMR1-interacting protein 1. (302 aa) |
| | mrps7 | 28S ribosomal protein S7, mitochondrial; Belongs to the universal ribosomal protein uS7 family. (228 aa) |
| | eif4ba | Eukaryotic translation initiation factor 4Ba. (616 aa) |
| | eif3s6ip | Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (576 aa) |
| | snrpf | Small nuclear ribonucleoprotein polypeptide F. (88 aa) |
| | clns1a | Chloride channel, nucleotide-sensitive, 1A. (249 aa) |
| | snrpg | Small nuclear ribonucleoprotein G. (76 aa) |
| | smx5 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa) |
| | rrp7a | Ribosomal RNA-processing 7 homolog A. (280 aa) |
| | ENSDARP00000131763 | Si:dkey-205h23.2. (439 aa) |
| | ago4 | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (863 aa) |
| | zgc:165603 | Zgc:165603 protein. (155 aa) |
| | xrcc5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (727 aa) |
| | bxdc2 | Brix domain-containing 2. (383 aa) |
| | eif3ha | Eukaryotic translation initiation factor 3 subunit H-A; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (335 aa) |
| | cdc73 | Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (530 aa) |
| | mrm2 | Mitochondrial rRNA methyltransferase 2. (259 aa) |
| | eif3ba | Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (681 aa) |
| | eif3f | Eukaryotic translation initiation factor 3, subunit F; Belongs to the eIF-3 subunit F family. (282 aa) |
| | srpk3 | SRSF protein kinase 3. (710 aa) |
| | znhit6 | Zinc finger HIT-type-containing 6. (367 aa) |
| | eif3ja | Eukaryotic translation initiation factor 3 subunit J-A; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (249 aa) |
| | setx | Senataxin. (2368 aa) |
| | rpsa | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (308 aa) |
| | nle1 | Notchless homolog 1 (Drosophila). (476 aa) |
| | scaf11 | SR-related CTD-associated factor 11. (1321 aa) |
| | rplp0 | 60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10; Belongs to the universal ribosomal protein uL10 family. (316 aa) |
| | prmt7 | Protein arginine N-methyltransferase 7; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being [...] (683 aa) |
| | ythdc1 | YTH domain-containing 1. (679 aa) |
| | eif3jb | Eukaryotic translation initiation factor 3 subunit J-B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (264 aa) |
| | ccdc105 | Coiled-coil domain-containing 105. (461 aa) |
| | rps27.2 | 40S ribosomal protein S27. (84 aa) |
| | ruvbl2 | RuvB-like 2; Has double-stranded DNA-stimulated ATPase activity. Has ATP-dependent DNA helicase (5' to 3') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). Represses gene activation mediated by beta-catenin. Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome- activated ATPase activity and catalyzes ATP-dependent nucleosome sliding (By similarity). Involved in the endoplasmic reticulum (ER)- associated degradation (ERAD) pathway where it negatively regulates expression of ER stress [...] (463 aa) |
| | luc7l | LUC7-like (S. cerevisiae). (364 aa) |
| | sf3b1 | Splicing factor 3b, subunit 1. (1315 aa) |
| | trnau1apb | tRNA selenocysteine 1-associated protein 1-like; Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Belongs to the RRM TRSPAP family. (316 aa) |
| | prpf18 | Pre-mRNA-splicing factor 18; Participates in the second step of pre-mRNA splicing. (342 aa) |
| | E9QC92_DANRE | Si:ch211-220i18.4; Belongs to the protein kinase superfamily. (440 aa) |
| | zrsr2 | Zinc finger (CCCH type), RNA-binding motif and serine/arginine-rich 2. (635 aa) |
| | celf4 | CUGBP Elav-like family member 4; RNA-binding protein that may be implicated in the regulation of pre-mRNA alternative splicing; Belongs to the CELF/BRUNOL family. (520 aa) |
| | cpsf6 | Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (558 aa) |
| | eral1 | GTPase Era, mitochondrial; Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly (By similarity); Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family. (447 aa) |
| | ddx28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28. (558 aa) |
| | prmt5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (631 aa) |
| | snu13a | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa) |
| | isy1 | ISY1-splicing factor homolog. (285 aa) |
| | celf5a | Cugbp, Elav-like family member 5a. (528 aa) |
| | eif3k | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (219 aa) |
| | zgc:158803 | Zgc:158803 protein. (417 aa) |
| | rpl6 | Ribosomal protein L6. (265 aa) |
| | luc7l3 | LUC7-like 3 pre-mRNA-splicing factor. (462 aa) |
| | prpf19 | PRP19/PSO4 homolog (S. cerevisiae). (505 aa) |
| | mrps11 | Novel protein similar to mouse and human mitochondrial ribosomal protein S11 (MRPS11); Belongs to the universal ribosomal protein uS11 family. (199 aa) |
| | F1QGR8_DANRE | Si:dkey-48p11.3. (153 aa) |
| | snrnp200 | Small nuclear ribonucleoprotein 200 (U5). (2134 aa) |
| | polr2d | Polymerase (RNA) II (DNA directed) polypeptide D. (141 aa) |
| | snrpd3l | Small nuclear ribonucleoprotein Sm D3. (128 aa) |
| | crnkl1 | Crooked neck pre-mRNA-splicing factor 1. (753 aa) |
| | fastkd2 | FAST kinase domains 2. (629 aa) |
| | dhx30 | DEAH (Asp-Glu-Ala-His) box helicase 30. (1173 aa) |
| | pwp2h | PWP2 small subunit processome component. (937 aa) |
| | eif3bb | Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (667 aa) |
| | nop2 | NOP2 nucleolar protein homolog (yeast); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (739 aa) |
| | eif3s10 | Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1267 aa) |
| | rpl5b | Ribosomal protein L5b. (296 aa) |
| | eif3ea | Eukaryotic translation initiation factor 3 subunit E-A; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (446 aa) |
| | prpf3 | PRP3 pre-mRNA-processing factor 3 homolog (yeast). (699 aa) |
| | dhx29 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1379 aa) |
| | strap | Serine/threonine kinase receptor-associated protein. (329 aa) |
| | coil | Coilin p80. (532 aa) |
| | rrs1 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (346 aa) |
| | mrpl20 | Mitochondrial ribosomal protein L20; Belongs to the bacterial ribosomal protein bL20 family. (149 aa) |
| | F1REM4_DANRE | Si:ch211-114c17.1. (669 aa) |
| | gemin5 | Gem (nuclear organelle)-associated protein 5. (1440 aa) |
| | naf1 | Nuclear assembly factor 1 homolog (S. cerevisiae). (503 aa) |
| | ddx20 | Probable ATP-dependent RNA helicase DDX20; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins are trapped in an inactive complex. The SMN complex triggers the assembly of core snRNPs and their transport to the nucleus. May also pla [...] (811 aa) |
| | prpf6 | PRP6 pre-mRNA-processing factor 6 homolog (S. cerevisiae). (974 aa) |
| | nop53 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (473 aa) |
| | ENSDARP00000148068 | RRM domain-containing protein. (134 aa) |
| | ENSDARP00000148783 | Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (87 aa) |
| | denr | Density-regulated protein; May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity). (208 aa) |
| | gemin2 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (261 aa) |
| | sf3a1 | Novel protein similar to human splicing factor 3a, subunit 1, 120kD (SF3A1). (780 aa) |
| | ENSDARP00000151160 | Protein kinase domain-containing protein. (160 aa) |
| | celf5b | Cugbp, Elav-like family member 5b. (410 aa) |
| | ENSDARP00000153382 | Protein kinase domain-containing protein. (160 aa) |
| | ENSDARP00000153439 | Uncharacterized protein. (161 aa) |
| | puf60b | Poly(U)-binding-splicing factor PUF60-B; DNA- and RNA-binding protein, involved in transcription repression and pre-mRNA splicing. (520 aa) |
| | traf7 | TNF receptor-associated factor 7. (665 aa) |
| | ENSDARP00000154119 | Uncharacterized protein. (192 aa) |
| | LSM2 | Si:ch73-14h10.2. (95 aa) |
| | rpf2 | Ribosome production factor 2 homolog. (308 aa) |
| | abt1 | Activator of basal transcription 1. (305 aa) |
| | ruvbl1 | RuvB-like 1; Has single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity). Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP- dependent nucleosome sliding (By similarity). May act as a negative regulator of embryonic heart growth. Belongs to the RuvB family. (456 aa) |
| | eif6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (245 aa) |
| | nudt21 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (228 aa) |
| | pih1d2 | PIH1 domain-containing protein 2; Belongs to the PIH1 family. (322 aa) |
| | smn1 | Survival motor neuron protein 1; The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. It may also play a role in the metabolism of snoRNPs. Required in motor neurons and proprioceptive neurons to ensure correct U12 intron splicing and proper levels of tmem41b mRNA. Required for the maturation of motor neuron axonal branches and dendrites. (281 aa) |
| | eif3i | Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (325 aa) |
| | eif5 | Eukaryotic translation initiation factor 5. (429 aa) |
| | snrpb | Small nuclear ribonucleoprotein-associated protein. (239 aa) |
| | eif3m | Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (375 aa) |
| | eif3g | Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (293 aa) |
| | eif2s3 | Eukaryotic translation initiation factor 2 subunit 3; As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In o [...] (472 aa) |
| | snrpd1 | Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa) |
| | rps27.1 | 40S ribosomal protein S27. (84 aa) |
| | znhit3 | Zinc finger, HIT-type-containing 3. (151 aa) |
