(25 nodes) Cytosolic small ribosomal subunit network (Danio rerio)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Your Input:
	rps21	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (81 aa)
	rps27.1	40S ribosomal protein S27. (84 aa)
	rps29	Ribosomal protein S29. (56 aa)
	rps5	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa)
	rps27.2	40S ribosomal protein S27. (84 aa)
	rps8a	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
	mrps11	Novel protein similar to mouse and human mitochondrial ribosomal protein S11 (MRPS11); Belongs to the universal ribosomal protein uS11 family. (199 aa)
	rps26	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa)
	dhx29	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1379 aa)
	rps4x	40S ribosomal protein S4, X isoform; Belongs to the eukaryotic ribosomal protein eS4 family. (263 aa)
	rps28	40S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family. (69 aa)
	rps2	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (280 aa)
	rpsa	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (308 aa)
	rps25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (124 aa)
	eif2a	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (580 aa)
	rps3a	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (267 aa)
	rps15a	40S ribosomal protein S15a; Structural component of the ribosome (By similarity). Required for erythropoiesis during embryonic development. (130 aa)
	rps7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
	rps26l	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa)
	rps9	Ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
	rps27l	40S ribosomal protein S27. (84 aa)
	faua	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (133 aa)
	rps23	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	rps6	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
	eif2d	Eukaryotic translation initiation factor 2D. (590 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dhx29	eif2d	ENSDARP00000107280	ENSDARP00000009582	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Eukaryotic translation initiation factor 2D.	0.601
eif2a	faua	ENSDARP00000132954	ENSDARP00000141629	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.	0.597
eif2a	mrps11	ENSDARP00000132954	ENSDARP00000097569	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	Novel protein similar to mouse and human mitochondrial ribosomal protein S11 (MRPS11); Belongs to the universal ribosomal protein uS11 family.	0.584
eif2a	rps15a	ENSDARP00000132954	ENSDARP00000108197	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S15a; Structural component of the ribosome (By similarity). Required for erythropoiesis during embryonic development.	0.571
eif2a	rps2	ENSDARP00000132954	ENSDARP00000117673	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.580
eif2a	rps21	ENSDARP00000132954	ENSDARP00000031181	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.	0.542
eif2a	rps23	ENSDARP00000132954	ENSDARP00000035273	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.	0.630
eif2a	rps25	ENSDARP00000132954	ENSDARP00000124711	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.541
eif2a	rps26	ENSDARP00000132954	ENSDARP00000105770	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.544
eif2a	rps26l	ENSDARP00000132954	ENSDARP00000111782	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.562
eif2a	rps27.1	ENSDARP00000132954	ENSDARP00000029079	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S27.	0.572
eif2a	rps27.2	ENSDARP00000132954	ENSDARP00000072300	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S27.	0.577
eif2a	rps27l	ENSDARP00000132954	ENSDARP00000140190	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S27.	0.577
eif2a	rps28	ENSDARP00000132954	ENSDARP00000115796	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family.	0.540
eif2a	rps29	ENSDARP00000132954	ENSDARP00000060443	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	Ribosomal protein S29.	0.596
eif2a	rps3a	ENSDARP00000132954	ENSDARP00000051762	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family.	0.484
eif2a	rps4x	ENSDARP00000132954	ENSDARP00000108089	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S4, X isoform; Belongs to the eukaryotic ribosomal protein eS4 family.	0.635
eif2a	rps5	ENSDARP00000132954	ENSDARP00000063788	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.	0.574
eif2a	rps6	ENSDARP00000132954	ENSDARP00000011148	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.563
eif2a	rps7	ENSDARP00000132954	ENSDARP00000109497	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	0.596

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