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| | gsna | Gelsolin a. (729 aa) |
| | nckap1 | Nck-associated protein 1; Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1 (By similarity). (1134 aa) |
| | pkn2 | Serine/threonine-protein kinase N2. (1005 aa) |
| | ENSDARP00000149939 | Si:dkey-40c11.2. (771 aa) |
| | arhgef7a | Rho guanine nucleotide exchange factor (GEF) 7a. (859 aa) |
| | wasf1 | WASP family member 1. (498 aa) |
| | PKN2 | Serine/threonine-protein kinase N2; Pkc-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. May play a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion and transcription activation signaling processes (By similarity). (984 aa) |
| | UNC5C | Si:ch73-72b7.1. (813 aa) |
| | phactr4a-2 | Phosphatase and actin regulator 4A; Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway (By similarity). (118 aa) |
| | coro1cb | Coronin; Belongs to the WD repeat coronin family. (474 aa) |
| | carmil3 | Capping protein regulator and myosin 1 linker 3. (1384 aa) |
| | ENSDARP00000143947 | KIND domain-containing protein. (225 aa) |
| | flot1a | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (438 aa) |
| | inppl1b | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...] (1226 aa) |
| | ENSDARP00000142109 | Si:dkey-280e21.3. (652 aa) |
| | vaspa | Vasodilator-stimulated phosphoprotein a. (412 aa) |
| | snx2 | Sorting nexin 2. (506 aa) |
| | ablim3 | Actin-binding LIM protein family, member 3. (684 aa) |
| | clrn1 | Clrn1 protein. (232 aa) |
| | apc | APC regulator of WNT-signaling pathway. (2754 aa) |
| | ptpn13 | Protein tyrosine phosphatase non-receptor type 13. (1302 aa) |
| | cib1 | Calcium and integrin-binding 1 (calmyrin). (188 aa) |
| | lrrc1 | Leucine-rich repeat-containing 1. (438 aa) |
| | baiap2b | BAR/IMD domain-containing adaptor protein 2b. (401 aa) |
| | phactr4a | Phosphatase and actin regulator 4A. (1011 aa) |
| | snx1b | Sorting nexin 1b. (493 aa) |
| | capgb | Capping protein (actin filament), gelsolin-like b. (345 aa) |
| | LOC101883470 | Capping protein regulator and myosin 1 linker 1. (106 aa) |
| | parvab | Zgc:162217 protein. (367 aa) |
| | avil | Zgc:136857. (811 aa) |
| | evlb | Enah/Vasp-like b. (359 aa) |
| | ppp1r9bb | Protein phosphatase 1, regulatory subunit 9Bb. (801 aa) |
| | coro6 | Coronin; Belongs to the WD repeat coronin family. (436 aa) |
| | inppl1a | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...] (1003 aa) |
| | ppp1r9ba | Protein phosphatase 1, regulatory subunit 9Ba. (803 aa) |
| | cdc42 | Cell division cycle 42. (191 aa) |
| | cd44b | CD44 molecule (Indian blood group) b. (405 aa) |
| | rac1l-2 | Rac family small GTPase 1,-like. (229 aa) |
| | R4GED8_DANRE | Si:ch211-1f22.2. (190 aa) |
| | Rac1l | Si:ch211-1f22.1. (192 aa) |
| | I3ITM8_DANRE | Si:ch73-362m14.4. (501 aa) |
| | als2b | Alsin Rho guanine nucleotide exchange factor ALS2 b. (1681 aa) |
| | carmil2 | Capping protein regulator and myosin 1 linker 2. (1665 aa) |
| | cdc42l2 | Cell division cycle 42-like 2. (209 aa) |
| | cttnbp2nlb | CTTNBP2 N-terminal-like b. (582 aa) |
| | ppp1r9a | Protein phosphatase 1, regulatory subunit 9A. (1068 aa) |
| | si:dkey-5i3.5 | Si:dkey-5i3.5. (277 aa) |
| | nf2a | Similar to neurofibromin 2. (593 aa) |
| | ptpn20 | Protein tyrosine phosphatase non-receptor type 20. (372 aa) |
| | tsc1b | TSC complex subunit 1b. (1228 aa) |
| | plekhh2 | Pleckstrin homology domain-containing, family H (with MyTH4 domain) member 2. (1420 aa) |
| | F1QZR0_DANRE | Si:dkey-21o19.2. (159 aa) |
| | fam89b | Family with sequence similarity 89 member B. (174 aa) |
| | abi1a | Abl-interactor 1a. (483 aa) |
| | nrbp1 | Nuclear receptor-binding protein 1. (519 aa) |
| | wasf3a | WASP family member 3a. (433 aa) |
| | stmn2b | Stathmin; Belongs to the stathmin family. (180 aa) |
| | plce1 | Phospholipase C, epsilon 1. (2248 aa) |
| | unc5c | Unc-5 netrin receptor C. (746 aa) |
| | rac3a | Ras-related C3 botulinum toxin substrate 3 (Rho family, small GTP binding protein Rac3). (192 aa) |
| | cd44a | CD44 molecule (Indian blood group) a. (392 aa) |
| | rac3b | Rac family small GTPase 3b. (192 aa) |
| | rac2 | Rac family small GTPase 2. (219 aa) |
| | caprin1a | Cell cycle-associated protein 1a. (670 aa) |
| | rac1b | Ras-related C3 botulinum toxin substrate 1-like protein. (192 aa) |
| | wasf2 | WASP family member 2. (486 aa) |
| | kitlga | Kit ligand a. (272 aa) |
| | arhgef7b | Rho guanine nucleotide exchange factor (GEF) 7b. (799 aa) |
| | ajuba | Ajuba LIM protein. (688 aa) |
| | rapgef3 | Rap guanine nucleotide exchange factor (GEF) 3. (867 aa) |
| | als2a | Alsin Rho guanine nucleotide exchange factor ALS2 a. (1662 aa) |
| | rac1a | Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1). (192 aa) |
| | flot1b | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (425 aa) |
| | stmn2a | Stathmin; Belongs to the stathmin family. (180 aa) |
| | abitram | Protein Abitram; May regulate actin polymerization, filopodia dynamics and arborization of neurons; Belongs to the ABITRAM family. (177 aa) |
| | podxl | Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (445 aa) |
| | zgc:109889 | Zgc:109889 protein. (279 aa) |
| | phactr2 | Phosphatase and actin regulator. (570 aa) |
| | arpin | Arpin; Regulates actin polymerization by inhibiting the actin- nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors (By similarity). Involved in steering cell migration by controlling its directional persistence. Belongs to the Arpin family. (226 aa) |
| | dbn1 | Drebrin 1. (553 aa) |
| | pdlim4 | PDZ and LIM domain 4. (349 aa) |
| | caprin1b | Cell cycle-associated protein 1b. (695 aa) |
| | vaspb | Vasodilator-stimulated phosphoprotein b. (445 aa) |
| | ppp1r9ala | Protein phosphatase 1 regulatory subunit 9A-like A. (1332 aa) |
| | abi3b | ABI family, member 3b. (415 aa) |
| | apc2 | APC regulator of WNT-signaling pathway 2. (2105 aa) |
| | abi1b | Abl-interactor 1b. (502 aa) |
| | wasf3b | WASP family member 3b. (481 aa) |
| | baiap2a | BAR/IMD domain-containing adaptor protein 2a. (514 aa) |
| | igf2bp1 | Insulin-like growth factor 2 mRNA-binding protein 1; RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Plays a direct role in the transport and translation of transcripts required for axonal regeneration in adult sensory neurons (By similarity). Regulates localized beta- actin/AC [...] (598 aa) |
| | abi3a | ABI family, member 3a. (454 aa) |
| | abi2a | Abl-interactor 2a. (394 aa) |
| | ilk | Integrin-linked kinase. (452 aa) |
| | cdk5 | Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | coro1a | Coronin; Belongs to the WD repeat coronin family. (455 aa) |
| | snx1a | Sorting nexin 1a. (659 aa) |
| | cttnbp2nla | CTTNBP2 N-terminal-like a. (494 aa) |
| | scrib | Protein scribble homolog; Scaffold protein involved in different aspects of polarized cells differentiation regulating epithelial and neuronal morphogenesis. Regulates the caudal migration of the nVII motor neurons. Required for convergent extension movements during gastrulation. (1724 aa) |
| | abi2b | Abl-interactor 2b. (461 aa) |
| | cyfip1 | Cytoplasmic FMR1-interacting protein 1 homolog; Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA (By similarity); Belongs to the CYFIP family. (1253 aa) |
| | parvaa | Parvin, alpha a. (372 aa) |
| | rac1l | Rac family small GTPase 1,-like. (188 aa) |
| | vil1 | Villin 1. (834 aa) |
| | cdc42l | Cell division cycle 42,-like. (191 aa) |
| | shtn1 | Shootin-1; Involved in the generation of internal asymmetric signals required for neuronal polarization and neurite outgrowth. Belongs to the shootin family. (544 aa) |
| | hax1 | HCLS1-associated protein X-1. (286 aa) |
| | evla | Enah/Vasp-like a. (387 aa) |
| | capga | Capping protein (actin filament), gelsolin-like a. (350 aa) |
| | sh3rf1 | E3 ubiquitin-protein ligase SH3RF1; Has E3 ubiquitin-protein ligase activity. In the absence of an external substrate, it can catalyze self-ubiquitination. Acts as a scaffold protein that contributes to the effective activation of the JNK signaling pathway; Belongs to the SH3RF family. (880 aa) |
| | fermt2 | Fermitin family homolog 2; Scaffolding protein that enhances integrin activation mediated by TLN1 and/or TLN2, but activates integrins only weakly by itself. Binds to membranes enriched in phosphoinositides. Enhances integrin-mediated cell adhesion onto the extracellular matrix and cell spreading; this requires both its ability to interact with integrins and with phospholipid membranes. Required for the assembly of focal adhesions. Participates in the connection between extracellular matrix adhesion sites and the actin cytoskeleton and also in the orchestration of actin assembly and ce [...] (684 aa) |
| | vill | Villin-like. (850 aa) |
| | gsnb | Gelsolin b. (728 aa) |
| | rab13 | Ras-related protein Rab-13; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may be involved in endocytic recycling and may regulate the transport to the plasma membrane of transmembrane proteins. May regulate the assembly and the activity of tight jun [...] (200 aa) |
| | srgap2 | SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. May play a role in different aspects of neuronal morphogenesis and migration. This includes the biogenesis of neurites, where it could be required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. May also stimulate the branching of the leading process and negatively regulates neuron migration. In non-neuronal cells, it may also play a role in cell migration by reg [...] (1100 aa) |
| | phactr4b | Phosphatase and actin regulator 4B; Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway (By similarity). (754 aa) |
| | tescb | Tescalcin b. (216 aa) |
| | rufy3 | RUN and FYVE domain-containing 3. (470 aa) |
| | tesca | Tescalcin a. (218 aa) |
| | tsc1a | TSC complex subunit 1a. (1128 aa) |
| | nf2b | Neurofibromin 2b (merlin). (586 aa) |
| | zgc:66426 | Zgc:66426. (231 aa) |
| | dbnlb | Drebrin-like b. (476 aa) |
| | dbnla | Drebrin-like a. (496 aa) |
| | coro1ca | Coronin-1C-A; Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (Probable). Increases the presence of activated RAC1 at the leading edge of migrating cells. Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments. Plays a role in endoplasmic reticulum-associated endosome fission: endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane. [...] (474 aa) |
| | itgb1bp1 | Integrin beta-1-binding protein 1. (198 aa) |
| | nav3 | Neuron navigator 3; May be involved in neuron regeneration; Belongs to the Nav/unc-53 family. (2269 aa) |
| | dag1 | Dystroglycan 1. (866 aa) |
| | kptn | Kaptin (actin-binding protein). (436 aa) |
| | enah | ENAH actin regulator. (804 aa) |
| | parvb | Parvin, beta. (365 aa) |
| | phactr1 | Phosphatase and actin regulator. (542 aa) |
| | arhgef6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. (766 aa) |
| | cdh2 | Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion (By similarity). Cadherins contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development. Required for normal neural tube morphogenesis. Required to allow mid- and hindbrain neurons to reach and maintain their appropriate positions within the neural tube by restricting neuronal motility within the embryonic mid- and hindbrain. (893 aa) |
| | nradd | Neurotrophin receptor-associated death domain. (413 aa) |
