STRINGSTRING
ndst3 ndst3 LOC108179064 LOC108179064 extl3 extl3 b3gat3 b3gat3 dse dse ndst2b ndst2b ext1b ext1b ext1a ext1a ndst1b ndst1b hs2st1a hs2st1a hs6st1a hs6st1a ugdh ugdh glcea glcea sulf2a sulf2a hs6st2 hs6st2 sulf2b sulf2b sulf1 sulf1 sgsh sgsh xylt1 xylt1 ext2 ext2 uxs1 uxs1 hs6st3b hs6st3b hs2st1b hs2st1b ndst1a ndst1a xylt2 xylt2 glceb glceb hs6st3a hs6st3a hs6st1b hs6st1b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ndst3N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3. (874 aa)
LOC108179064Exostosin-1c; Glycosyltransferase required for the biosynthesis of heparan- sulfate. (312 aa)
extl3Exostosin-like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family. (917 aa)
b3gat3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (330 aa)
dseDermatan sulfate epimerase. (949 aa)
ndst2bN-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2b. (893 aa)
ext1bExostosin-1b; Glycosyltransferase required for the biosynthesis of heparan- sulfate. (741 aa)
ext1aExostosin-1a; Glycosyltransferase required for the biosynthesis of heparan- sulfate. (730 aa)
ndst1bN-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b. (886 aa)
hs2st1aHeparan sulfate 2-O-sulfotransferase 1a. (354 aa)
hs6st1aHeparan-sulfate 6-O-sulfotransferase 1-A; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (413 aa)
ugdhUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (493 aa)
glceaGlucuronic acid epimerase a. (585 aa)
sulf2aExtracellular sulfatase. (873 aa)
hs6st2Heparan-sulfate 6-O-sulfotransferase 2; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Required for muscle development and angiogenesis. (468 aa)
sulf2bExtracellular sulfatase. (885 aa)
sulf1Sulfatase FP1c. (1099 aa)
sgshN-sulfoglucosamine sulfohydrolase (sulfamidase). (511 aa)
xylt1Xylosyltransferase I. (919 aa)
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
uxs1UDP-glucuronic acid decarboxylase 1; Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis (By similarity). Essential during embryogenesis for craniofacial development. Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. (418 aa)
hs6st3bHeparan-sulfate 6-O-sulfotransferase 3-B; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (419 aa)
hs2st1bHeparan sulfate 2-O-sulfotransferase 1b. (356 aa)
ndst1aN-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1a. (869 aa)
xylt2Xylosyltransferase II. (867 aa)
glcebD-glucuronyl C5-epimerase B; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. Plays a role in dorso-ventral axis specification during early development, together with glcea, where it may potentiate signaling via the BMP pathway. (586 aa)
hs6st3aHeparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (420 aa)
hs6st1bHeparan-sulfate 6-O-sulfotransferase 1-B; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (407 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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