STRINGSTRING
ENSDARP00000151202 ENSDARP00000151202 gata1a gata1a ankhb ankhb bmpr1aa bmpr1aa dkk1a dkk1a mdkb mdkb bmp2k bmp2k smad7 smad7 tgfb3 tgfb3 ccn1 ccn1 ahsg1 ahsg1 rflna rflna pkdcca pkdcca mdka mdka pkdccb pkdccb phospho1 phospho1 bmpr2a bmpr2a tgfb1a tgfb1a p2rx7 p2rx7 atraid atraid dhrs3b dhrs3b dhrs3a dhrs3a dkk1b dkk1b bmp4 bmp4 gata1b gata1b zmpste24 zmpste24 ano6 ano6 kremen1 kremen1 ptger4b ptger4b tmem119b tmem119b csf1b csf1b smad6b smad6b ahsg2 ahsg2 ptger4a ptger4a acvr2aa acvr2aa tgfb5 tgfb5 ptger4c ptger4c fam20ca fam20ca cyp26b1 cyp26b1 csf1a csf1a nbr1b nbr1b ankha ankha acvr2ba acvr2ba bmpr2b bmpr2b fam20cb fam20cb smad6a smad6a pth1a pth1a nbr1a nbr1a tgfb1b tgfb1b tgfb2 tgfb2 rflnb rflnb bmpr1bb bmpr1bb LOC100331938 LOC100331938 phospho2 phospho2 ecm1b ecm1b acvr2ab acvr2ab bmpr1ba bmpr1ba bmpr1ab bmpr1ab pth4 pth4 bmp16 bmp16 ENSDARP00000148390 ENSDARP00000148390
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSDARP00000151202Peptidase_M48_N domain-containing protein. (272 aa)
gata1aGATA-binding protein 1a. (418 aa)
ankhbProgressive ankylosis protein homolog B; Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter. Belongs to the ANKH family. (501 aa)
bmpr1aaReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa)
dkk1aDickkopf WNT-signaling pathway inhibitor 1a. (256 aa)
mdkbMidkine-related growth factor Mdk2. (147 aa)
bmp2kBMP2-inducible kinase. (645 aa)
smad7Mothers against decapentaplegic homolog. (372 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
ccn1Cellular communication network factor 1. (369 aa)
ahsg1Alpha-2-HS-glycoprotein 1. (455 aa)
rflnaFamily with sequence similarity 101, member A. (222 aa)
pkdccaProtein kinase domain-containing, cytoplasmic a. (516 aa)
mdkaMidkine-related growth factor Mdk1. (146 aa)
pkdccbProtein kinase domain-containing, cytoplasmic b. (481 aa)
phospho1Probable phosphatase phospho1; Probable phosphatase, involved in bone mineralization. Belongs to the HAD-like hydrolase superfamily. PHOSPHO family. (279 aa)
bmpr2aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1003 aa)
tgfb1aTransforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa)
atraidAll-trans retinoic acid-induced differentiation factor; Involved in osteoblast cell differentiation. May play a role in inducing the cell cycle arrest (By similarity). (230 aa)
dhrs3bDehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
dhrs3aDehydrogenase/reductase (SDR family) member 3a. (302 aa)
dkk1bDickkopf WNT-signaling pathway inhibitor 1b. (241 aa)
bmp4Bone morphogenetic protein 4. (400 aa)
gata1bGATA-binding protein 1b. (361 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (468 aa)
ano6Anoctamin. (910 aa)
kremen1Kringle-containing transmembrane protein 1. (465 aa)
ptger4bProstaglandin E receptor 4 (subtype EP4) b; Belongs to the G-protein coupled receptor 1 family. (497 aa)
tmem119bTransmembrane protein 119b. (294 aa)
csf1bColony-stimulating factor 1b (macrophage). (284 aa)
smad6bMothers against decapentaplegic homolog. (486 aa)
ahsg2Alpha-2-HS-glycoprotein 2. (386 aa)
ptger4aProstaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (403 aa)
acvr2aaSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (538 aa)
tgfb5Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
ptger4cProstaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (435 aa)
fam20caFAM20C golgi-associated secretory pathway kinase a. (545 aa)
cyp26b1Cytochrome P450 26B1; Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Appears to be involved in the inactivation of all-trans-retinoic acid (RA). Plays a role in skeletal development; Belongs to the cytochrome P450 family. (511 aa)
csf1aColony-stimulating factor 1a (macrophage). (526 aa)
nbr1bNBR1 autophagy cargo receptor b. (992 aa)
ankhaANKH inorganic pyrophosphate transport regulator a. (496 aa)
acvr2baSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
bmpr2bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1071 aa)
fam20cbFAM20C golgi-associated secretory pathway kinase b. (557 aa)
smad6aMothers against decapentaplegic homolog. (456 aa)
pth1aParathyroid hormone 1a. (102 aa)
nbr1aNBR1 autophagy cargo receptor a. (989 aa)
tgfb1bTransforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
tgfb2Transforming growth factor, beta 2. (413 aa)
rflnbRefilin B. (194 aa)
bmpr1bbSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (535 aa)
LOC100331938Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
phospho2Phosphatase, orphan 2. (241 aa)
ecm1bExtracellular matrix protein 1b. (499 aa)
acvr2abSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (439 aa)
bmpr1baSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
bmpr1abReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (535 aa)
pth4Parathyroid hormone 4; Neuroendocrine peptide which is produced by a subset of neurons in the hypothalamus. Activates the G-protein coupled receptors pth1ra, pth1rb and pth2r with similar affinity. Receptor binding stimulates intracellular cAMP production. Plays a role in bone mineralization by regulating expression of factors involved in phosphate homeostasis. Important for embryonic bone development. (121 aa)
bmp16Bone morphogenetic protein 16. (416 aa)
ENSDARP00000148390Uncharacterized protein. (113 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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