(63 nodes) Adult behavior network (Danio rerio)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	cd164	CD164 molecule, sialomucin. (167 aa)
	drd4-rs	Dopamine receptor D4-related sequence; Belongs to the G-protein coupled receptor 1 family. (418 aa)
	ctns	Cystinosin, lysosomal cystine transporter. (384 aa)
	tsc1a	TSC complex subunit 1a. (1128 aa)
	crhbp	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (321 aa)
	klhl4	Kelch-like family member 4. (327 aa)
	drd4b	Dopamine D4c receptor; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	oprd1b	Opioid receptor, delta 1b; Belongs to the G-protein coupled receptor 1 family. (375 aa)
	oprm1	Opioid receptor, mu 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	F1QSV1_DANRE	Si:ch73-352p4.8. (492 aa)
	glrbb	Glycine receptor beta subunit 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (494 aa)
	ghsra	Growth hormone secretagogue receptor a; Belongs to the G-protein coupled receptor 1 family. (360 aa)
	cdk5	Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	rnf180	Ring finger protein 180. (458 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (468 aa)
	klhl5	Kelch-like family member 5. (769 aa)
	shank3a	SH3 and multiple ankyrin repeat domains 3a. (1509 aa)
	btbd9	BTB (POZ) domain-containing 9. (602 aa)
	ppp1r1b	Protein phosphatase 1, regulatory (inhibitor) subunit 1B. (189 aa)
	glrba	Glycine receptor betaZ subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (498 aa)
	sez6l2	Seizure-related 6 homolog (mouse)-like 2. (898 aa)
	bbs1	Bardet-Biedl syndrome 1. (588 aa)
	drd3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (466 aa)
	bbs4	Bardet-Biedl syndrome 4. (528 aa)
	mecp2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (524 aa)
	zgc:193505	Zgc:193505. (141 aa)
	fxn	Frataxin. (200 aa)
	agrp	Agouti-related neuropeptide. (126 aa)
	shank3b	SH3 and multiple ankyrin repeat domains 3b. (1631 aa)
	shank2b	SH3 and multiple ankyrin repeat domains 2b. (1800 aa)
	TPGS1	Zgc:92789. (267 aa)
	tsc1b	TSC complex subunit 1b. (1228 aa)
	sncga	Synuclein, gamma a; Belongs to the synuclein family. (111 aa)
	oprd1a	Opioid receptor, delta 1a; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	F1QV96_DANRE	Si:dkey-250l23.4. (363 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (289 aa)
	abat	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
	mafga	V-maf musculoaponeurotic fibrosarcoma oncogene family, protein g (Avian), 1. (162 aa)
	shank1	SH3 and multiple ankyrin repeat domains 1. (852 aa)
	sez6b	Seizure-related 6 homolog b. (1027 aa)
	appa	Amyloid beta (A4) precursor protein a. (194 aa)
	ntan1	N-terminal asparagine amidase. (54 aa)
	slc1a2b	Amino acid transporter. (564 aa)
	sez6a	Seizure-related 6 homolog a. (970 aa)
	ENSDARP00000136668	Ncstrn_small domain-containing protein. (599 aa)
	drd4a	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	homer1b	Homer scaffold protein 1b. (398 aa)
	slitrk6	SLIT and NTRK-like family, member 6. (830 aa)
	slc1a9	Amino acid transporter. (424 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (458 aa)
	mafgb	V-maf musculoaponeurotic fibrosarcoma oncogene homolog g (Avian), 2. (171 aa)
	slc7a11	Solute carrier family 7 member 11. (498 aa)
	slc1a2a	Amino acid transporter. (548 aa)
	shank2a	SH3 and multiple ankyrin repeat domains 2a. (1306 aa)
	ENSDARP00000146169	G_PROTEIN_RECEP_F1_2 domain-containing protein. (123 aa)
	hoxc10a	Homeobox C10a. (337 aa)
	LOC100331987	Seizure-related 6 homolog (mouse)-like. (937 aa)
	cnp	2',3'-cyclic nucleotide 3' phosphodiesterase. (443 aa)
	sncgb	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family. (114 aa)
	cntn2	Contactin 2. (1040 aa)
	en1b	Homeobox protein engrailed-like. (274 aa)
	ENSDARP00000151202	Peptidase_M48_N domain-containing protein. (272 aa)
	ENSDARP00000155841	G_PROTEIN_RECEP_F1_2 domain-containing protein. (108 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSDARP00000136668	appa	ENSDARP00000136668	ENSDARP00000130555	Ncstrn_small domain-containing protein.	Amyloid beta (A4) precursor protein a.	0.879
ENSDARP00000136668	cdk5	ENSDARP00000136668	ENSDARP00000073666	Ncstrn_small domain-containing protein.	Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily.	0.418
F1QSV1_DANRE	slc7a11	ENSDARP00000059439	ENSDARP00000142449	Si:ch73-352p4.8.	Solute carrier family 7 member 11.	0.902
agrp	crhbp	ENSDARP00000116390	ENSDARP00000037928	Agouti-related neuropeptide.	Corticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family.	0.458
agrp	ghsra	ENSDARP00000116390	ENSDARP00000073156	Agouti-related neuropeptide.	Growth hormone secretagogue receptor a; Belongs to the G-protein coupled receptor 1 family.	0.788
appa	ENSDARP00000136668	ENSDARP00000130555	ENSDARP00000136668	Amyloid beta (A4) precursor protein a.	Ncstrn_small domain-containing protein.	0.879
appa	cdk5	ENSDARP00000130555	ENSDARP00000073666	Amyloid beta (A4) precursor protein a.	Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily.	0.433
appa	cntn2	ENSDARP00000130555	ENSDARP00000149940	Amyloid beta (A4) precursor protein a.	Contactin 2.	0.556
appa	ghsra	ENSDARP00000130555	ENSDARP00000073156	Amyloid beta (A4) precursor protein a.	Growth hormone secretagogue receptor a; Belongs to the G-protein coupled receptor 1 family.	0.419
appa	prkn	ENSDARP00000130555	ENSDARP00000141580	Amyloid beta (A4) precursor protein a.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.480
bbs1	bbs4	ENSDARP00000104106	ENSDARP00000104870	Bardet-Biedl syndrome 1.	Bardet-Biedl syndrome 4.	0.995
bbs1	klhl4	ENSDARP00000104106	ENSDARP00000044388	Bardet-Biedl syndrome 1.	Kelch-like family member 4.	0.454
bbs1	klhl5	ENSDARP00000104106	ENSDARP00000083875	Bardet-Biedl syndrome 1.	Kelch-like family member 5.	0.454
bbs4	bbs1	ENSDARP00000104870	ENSDARP00000104106	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 1.	0.995
bbs4	klhl4	ENSDARP00000104870	ENSDARP00000044388	Bardet-Biedl syndrome 4.	Kelch-like family member 4.	0.435
bbs4	klhl5	ENSDARP00000104870	ENSDARP00000083875	Bardet-Biedl syndrome 4.	Kelch-like family member 5.	0.436
cdk5	ENSDARP00000136668	ENSDARP00000073666	ENSDARP00000136668	Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily.	Ncstrn_small domain-containing protein.	0.418
cdk5	appa	ENSDARP00000073666	ENSDARP00000130555	Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily.	Amyloid beta (A4) precursor protein a.	0.433
cdk5	ppp1r1b	ENSDARP00000073666	ENSDARP00000092432	Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily.	Protein phosphatase 1, regulatory (inhibitor) subunit 1B.	0.851
cdk5	prkn	ENSDARP00000073666	ENSDARP00000141580	Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.540

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