STRINGSTRING
cthrc1a cthrc1a cldn5b cldn5b cthrc1b cthrc1b si:dkey-3h3.3 si:dkey-3h3.3 abl1 abl1 men1 men1 pkd1b pkd1b X1WFS5_DANRE X1WFS5_DANRE ep300b ep300b X1WG91_DANRE X1WG91_DANRE E7FBV5_DANRE E7FBV5_DANRE spon1a spon1a nvl nvl spon1b spon1b trib3 trib3 derl1 derl1 pkd1a pkd1a abl2 abl2 cldn5a cldn5a appa appa bmp4 bmp4 vtnb vtnb bambia bambia vtna vtna poldip2 poldip2 cdk5 cdk5 sppl3 sppl3 zgc:66440 zgc:66440 rapgef6 rapgef6 rapgef2 rapgef2 LOC110437957 LOC110437957 bmp16 bmp16 adgrg1-2 adgrg1-2 prkn prkn bambib bambib ep300a ep300a spag8 spag8 ENSDARP00000135458 ENSDARP00000135458 ide ide ripk2 ripk2 pin1 pin1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cthrc1aCollagen triple helix repeat-containing 1a. (232 aa)
cldn5bClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
cthrc1bCollagen triple helix repeat-containing 1b. (233 aa)
si:dkey-3h3.3Si:dkey-3h3.3. (441 aa)
abl1Tyrosine-protein kinase. (1081 aa)
men1Multiple endocrine neoplasia I. (617 aa)
pkd1bPolycystic kidney disease 1b. (3827 aa)
X1WFS5_DANRESi:dkey-40c23.1. (542 aa)
ep300bE1A-binding protein p300 b. (2615 aa)
X1WG91_DANRESi:dkey-40c23.2. (967 aa)
E7FBV5_DANRESi:ch73-78o10.1. (178 aa)
spon1aSpondin 1a. (808 aa)
nvlNuclear VCP-like. (796 aa)
spon1bSpondin 1b. (804 aa)
trib3Tribbles pseudokinase 3. (348 aa)
derl1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (261 aa)
pkd1aPolycystic kidney disease 1a. (4346 aa)
abl2Tyrosine-protein kinase. (1135 aa)
cldn5aClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
appaAmyloid beta (A4) precursor protein a. (194 aa)
bmp4Bone morphogenetic protein 4. (400 aa)
vtnbVitronectin b. (449 aa)
bambiaBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (258 aa)
vtnaVitronectin a. (514 aa)
poldip2Polymerase (DNA-directed), delta-interacting protein 2. (376 aa)
cdk5Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
sppl3Signal peptide peptidase-like protein 3. (382 aa)
zgc:66440Zgc:66440. (384 aa)
rapgef6Rap guanine nucleotide exchange factor (GEF) 6. (1261 aa)
rapgef2Rap guanine nucleotide exchange factor (GEF) 2. (1619 aa)
LOC110437957CARD domain-containing protein. (201 aa)
bmp16Bone morphogenetic protein 16. (416 aa)
adgrg1-2Adhesion G protein-coupled receptor G1. (513 aa)
prknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (458 aa)
bambibBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (257 aa)
ep300aE1A-binding protein p300 a. (2679 aa)
spag8Sperm-associated antigen 8. (198 aa)
ENSDARP00000135458Si:dkey-40c23.2. (770 aa)
ideNovel protein similar to H.sapiens IDE, insulin-degrading enzyme (IDE, zgc:162603); Belongs to the peptidase M16 family. (998 aa)
ripk2Receptor-interacting serine-threonine kinase 2. (457 aa)
pin1Peptidyl-prolyl cis-trans isomerase. (141 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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