STRINGSTRING
bbs4 bbs4 atxn1l atxn1l mecp2 mecp2 cica cica uts1 uts1 mkks mkks eif4ebp2 eif4ebp2 gnb1l gnb1l npas4a npas4a kcnq1.1 kcnq1.1 slc6a4b slc6a4b slc6a4a slc6a4a atxn1a atxn1a shank3a shank3a brinp1 brinp1 ptchd1 ptchd1 en1b en1b shank2a shank2a kcnq1.2 kcnq1.2 pcm1 pcm1 rptor rptor shank1 shank1 cln8 cln8 atxn1b atxn1b shank2b shank2b shank3b shank3b cicb cicb ptchd4 ptchd4 npas4b npas4b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bbs4Bardet-Biedl syndrome 4. (528 aa)
atxn1lAtaxin 1-like. (765 aa)
mecp2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (524 aa)
cicaCapicua transcriptional repressor a. (2492 aa)
uts1Urotensin 1. (138 aa)
mkksMcKusick-Kaufman syndrome. (563 aa)
eif4ebp2Eukaryotic translation initiation factor 4E-binding protein 2. (113 aa)
gnb1lGuanine nucleotide-binding protein (G protein), beta polypeptide 1-like. (323 aa)
npas4aNeuronal PAS domain-containing protein 4A; Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contextual memory in the hyppocampus. Plays a key role in the structural and functional plasticity of neurons. Acts as an early-response transcription factor in both excitatory and inhibitory neurons, where it induces distinct but overlapping sets of late- response genes in these two types of neurons, allowing the synapses that form on inhibitory and excitatory neurons to be modified by neuronal act [...] (933 aa)
kcnq1.1Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (655 aa)
slc6a4bTransporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (591 aa)
slc6a4aTransporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (646 aa)
atxn1aAtaxin 1a. (781 aa)
shank3aSH3 and multiple ankyrin repeat domains 3a. (1509 aa)
brinp1Bone morphogenetic protein/retinoic acid-inducible neural-specific 1. (759 aa)
ptchd1Patched domain-containing protein 1. (887 aa)
en1bHomeobox protein engrailed-like. (274 aa)
shank2aSH3 and multiple ankyrin repeat domains 2a. (1306 aa)
kcnq1.2Potassium voltage-gated channel, KQT-like subfamily, member 1.2; Belongs to the potassium channel family. (531 aa)
pcm1Pericentriolar material 1. (2018 aa)
rptorRegulatory-associated protein of MTOR, complex 1. (1363 aa)
shank1SH3 and multiple ankyrin repeat domains 1. (852 aa)
cln8CLN8 transmembrane ER and ERGIC protein. (289 aa)
atxn1bAtaxin 1b. (827 aa)
shank2bSH3 and multiple ankyrin repeat domains 2b. (1800 aa)
shank3bSH3 and multiple ankyrin repeat domains 3b. (1631 aa)
cicbCapicua transcriptional repressor b. (2623 aa)
ptchd4Patched domain-containing protein 1. (897 aa)
npas4bNeuronal PAS domain-containing protein 4B; Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contextual memory in the hyppocampus. Plays a key role in the structural and functional plasticity of neurons. Acts as an early-response transcription factor in both excitatory and inhibitory neurons, where it induces distinct but overlapping sets of late- response genes in these two types of neurons, allowing the synapses that form on inhibitory and excitatory neurons to be modified by neuronal act [...] (538 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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