STRINGSTRING
marveld2a marveld2a exoc4 exoc4 hsp90aa1.1 hsp90aa1.1 hsp90aa1.2 hsp90aa1.2 tspan2a tspan2a plp1b plp1b prkcz prkcz cldn5a cldn5a pllp pllp mpz mpz cldn5b cldn5b marveld2b marveld2b mbpb mbpb plp1a plp1a tspan2b tspan2b cnp cnp cntn2 cntn2 sirt2 sirt2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
marveld2aMARVEL domain-containing 2a. (545 aa)
exoc4Exocyst complex component 4. (968 aa)
hsp90aa1.1Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] (725 aa)
hsp90aa1.2Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (734 aa)
tspan2aTetraspanin. (211 aa)
plp1bProteolipid protein 1b. (279 aa)
prkczProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
cldn5aClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
pllpNovel protein similar to vertebrate transmembrane 4 superfamily member 11 (Plasmolipin) (TM4SF11). (173 aa)
mpzMyelin protein zero. (203 aa)
cldn5bClaudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
marveld2bMARVEL domain-containing 2b. (572 aa)
mbpbMyelin basic protein b. (133 aa)
plp1aProteolipid protein 1a. (245 aa)
tspan2bTetraspanin. (227 aa)
cnp2',3'-cyclic nucleotide 3' phosphodiesterase. (443 aa)
cntn2Contactin 2. (1040 aa)
sirt2NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors (By similarity). Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter. Thereby con [...] (379 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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