STRINGSTRING
bzw1a bzw1a arglu1b arglu1b arglu1a arglu1a ctnnal1 ctnnal1 bmpr2a bmpr2a cdh2 cdh2 phldb1a phldb1a bzw2 bzw2 pkp4 pkp4 cdh26.1 cdh26.1 ctnnd1 ctnnd1 ctnnd2a ctnnd2a ptprb ptprb LOC100536716 LOC100536716 ctnnb1 ctnnb1 LOC100534755 LOC100534755 chmp5b chmp5b CDH18 CDH18 cdh28 cdh28 ubfd1 ubfd1 cdh30 cdh30 cdh1 cdh1 psen1 psen1 ENSDARP00000136182 ENSDARP00000136182 bzw1b bzw1b cdh4 cdh4 ptpro-2 ptpro-2 ptpro ptpro ENSDARP00000133044 ENSDARP00000133044 ctnna1 ctnna1 numbl numbl ptprjb.2 ptprjb.2 ptprjb.1 ptprjb.1 ptprja ptprja cdh31 cdh31 ptprh ptprh txndc9 txndc9 LOC569071 LOC569071 cdh6 cdh6 arvcfb arvcfb phldb2b phldb2b cdh13 cdh13 golga3 golga3 chmp5a chmp5a cdh12a cdh12a micall1b.2 micall1b.2 E7EY81_DANRE E7EY81_DANRE LOC101882238 LOC101882238 E7F1J7_DANRE E7F1J7_DANRE pkp3a pkp3a bmpr2b bmpr2b cdh5 cdh5 phldb1b phldb1b pkp3b pkp3b numb numb ctnna2 ctnna2 cdh18a cdh18a cdh15 cdh15 ctnnd2b ctnnd2b jupb jupb ctnnb2 ctnnb2 F1R963_DANRE F1R963_DANRE cdh11 cdh11 cdh10a cdh10a cdh27 cdh27 pkp1b pkp1b glod4 glod4 F1QXE0_DANRE F1QXE0_DANRE LOC100329245 LOC100329245 cdh7a cdh7a pkp2 pkp2 jupa jupa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bzw1aBasic leucine zipper and W2 domain-containing protein 1-A; Enhances histone H4 gene transcription but does not seem to bind DNA directly. (419 aa)
arglu1bArginine and glutamate-rich protein 1-B; Belongs to the UPF0430 family. (269 aa)
arglu1aArginine and glutamate-rich protein 1-A; Belongs to the UPF0430 family. (251 aa)
ctnnal1Catenin (cadherin-associated protein), alpha-like 1. (754 aa)
bmpr2aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1003 aa)
cdh2Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion (By similarity). Cadherins contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development. Required for normal neural tube morphogenesis. Required to allow mid- and hindbrain neurons to reach and maintain their appropriate positions within the neural tube by restricting neuronal motility within the embryonic mid- and hindbrain. (893 aa)
phldb1aPleckstrin homology-like domain, family B, member 1a. (1455 aa)
bzw2Basic leucine zipper and W2 domain-containing protein 2; May be involved in neuronal differentiation. (421 aa)
pkp4Plakophilin 4. (1136 aa)
cdh26.1Cadherin 26, tandem duplicate 1. (873 aa)
ctnnd1Catenin (cadherin-associated protein), delta 1. (931 aa)
ctnnd2aCatenin (cadherin-associated protein), delta 2a. (1221 aa)
ptprbProtein tyrosine phosphatase receptor type b. (1892 aa)
LOC100536716Cadherin 22; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
ctnnb1Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] (789 aa)
LOC100534755Uncharacterized protein. (616 aa)
chmp5bCharged multivesicular body protein 5; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity). (220 aa)
CDH18Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. (816 aa)
cdh28Cadherin 28. (795 aa)
ubfd1Ubiquitin family domain-containing 1. (279 aa)
cdh30Cadherin 30. (740 aa)
cdh1Cadherin 1, type 1, E-cadherin (epithelial); Cadherins are calcium-dependent cell adhesion proteins. (877 aa)
psen1Presenilin-1; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins (By similarity); Belongs to the peptidase A22A family. (456 aa)
ENSDARP00000136182Si:ch211-194m7.8. (447 aa)
bzw1bBasic leucine zipper and W2 domain-containing protein 1-B; Enhances histone H4 gene transcription but does not seem to bind DNA directly. (418 aa)
cdh4Cadherin 4, type 1, R-cadherin (retinal); Cadherins are calcium-dependent cell adhesion proteins. (931 aa)
ptpro-2Protein tyrosine phosphatase receptor type O. (866 aa)
ptproProtein tyrosine phosphatase receptor type O. (385 aa)
ENSDARP00000133044Si:ch211-194m7.4. (387 aa)
ctnna1Catenin (cadherin-associated protein), alpha 1. (907 aa)
numblNUMB-like endocytic adaptor protein. (618 aa)
ptprjb.2Protein tyrosine phosphatase receptor type Jb, tandem duplicate 2. (320 aa)
ptprjb.1Protein tyrosine phosphatase receptor type Jb, tandem duplicate 1. (311 aa)
ptprjaProtein tyrosine phosphatase receptor type Ja. (1650 aa)
cdh31Cadherin 31; Cadherins are calcium-dependent cell adhesion proteins. (842 aa)
ptprhProtein tyrosine phosphatase receptor type H. (779 aa)
txndc9Thioredoxin domain-containing 9. (226 aa)
LOC569071Protein tyrosine phosphatase receptor type H. (770 aa)
cdh6Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
arvcfbARVCF delta catenin family member b. (986 aa)
phldb2bPleckstrin homology-like domain, family B, member 2b. (1318 aa)
cdh13Cadherin 13, H-cadherin (heart). (661 aa)
golga3Golgin A3. (1494 aa)
chmp5aCharged multivesicular body protein 5a. (251 aa)
cdh12aCadherin 12, type 2a (N-cadherin 2); Cadherins are calcium-dependent cell adhesion proteins. (800 aa)
micall1b.2MICAL-like 1b, duplicate 2. (686 aa)
E7EY81_DANRESi:ch211-173a9.6. (466 aa)
LOC101882238Cadherin 26, tandem duplicate 2. (852 aa)
E7F1J7_DANRESi:ch211-147m6.1. (387 aa)
pkp3aPlakophilin 3a. (869 aa)
bmpr2bReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1071 aa)
cdh5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (767 aa)
phldb1bPleckstrin homology-like domain, family B, member 1b. (1443 aa)
pkp3bPlakophilin 3b. (791 aa)
numbNUMB endocytic adaptor protein. (680 aa)
ctnna2Catenin alpha-2; May function as a linker between cadherin adhesion receptors and the cytoskeleton to regulate cell-cell adhesion and differentiation in the nervous system; Belongs to the vinculin/alpha-catenin family. (865 aa)
cdh18aCadherin 18, type 2a. (108 aa)
cdh15Cadherin 15, type 1, M-cadherin (myotubule); Cadherins are calcium-dependent cell adhesion proteins. (792 aa)
ctnnd2bCatenin (cadherin-associated protein), delta 2b. (1210 aa)
jupbJunction plakoglobin b. (726 aa)
ctnnb2Catenin, beta 2. (778 aa)
F1R963_DANRESi:dkey-30c15.12; Cadherins are calcium-dependent cell adhesion proteins. (737 aa)
cdh11Cadherin 11, type 2, OB-cadherin (osteoblast); Cadherins are calcium-dependent cell adhesion proteins. (800 aa)
cdh10aCadherin 10, type 2a (T2-cadherin); Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
cdh27Cadherin 27. (813 aa)
pkp1bPlakophilin 1b. (736 aa)
glod4Glyoxalase domain-containing 4. (298 aa)
F1QXE0_DANRESi:ch211-173a9.6. (476 aa)
LOC100329245Cadherin 7b; Cadherins are calcium-dependent cell adhesion proteins. (668 aa)
cdh7aCdh7 protein; Cadherins are calcium-dependent cell adhesion proteins. (787 aa)
pkp2Plakophilin 2. (815 aa)
jupaJunction plakoglobin a. (729 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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