STRINGSTRING
armc9 armc9 ENSDARP00000153433 ENSDARP00000153433 scube3 scube3 uchl5 uchl5 scube1 scube1 gas8 gas8 ulk3 ulk3 tubd1 tubd1 fam92a1 fam92a1 dlg5b.1 dlg5b.1 dlg5a dlg5a ttc23 ttc23 stk36 stk36 smo smo txndc15 txndc15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
armc9LisH domain-containing protein ARMC9; Acts as a positive regulator of hedgehog (Hh) signaling (By similarity). Involved in ciliogenesis. (544 aa)
ENSDARP00000153433annotation not available (144 aa)
scube3Signal peptide, CUB domain, EGF-like 3. (1002 aa)
uchl5Ubiquitin carboxyl-terminal hydrolase. (329 aa)
scube1Signal peptide, CUB domain, EGF-like 1. (1067 aa)
gas8Dynein regulatory complex subunit 4; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper slow muscle development and positively regulates ciliary smoothened (SMO)-dependent Hedgehog ( [...] (475 aa)
ulk3Unc-51-like kinase 3. (407 aa)
tubd1Tubulin, delta 1; Belongs to the tubulin family. (446 aa)
fam92a1Protein FAM92A; Acts as a positive regulator of ciliary hedgehog signaling (By similarity). Plays a role in ciliogenesis (By similarity). (295 aa)
dlg5b.1Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family. (1888 aa)
dlg5aDiscs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1926 aa)
ttc23Tetratricopeptide repeat domain 23. (463 aa)
stk36Serine/threonine kinase 36 (fused homolog, Drosophila). (1231 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa)
txndc15Interferon regulatory factor 1b. (286 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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