STRINGSTRING
fez1 fez1 nfe2 nfe2 syngr1a syngr1a parp1 parp1 atm atm ercc4 ercc4 exoc4 exoc4 syngr3a syngr3a mnat1 mnat1 stx5a stx5a tsc1a tsc1a pex19 pex19 hax1 hax1 id1 id1 alox5ap alox5ap exoc2 exoc2 snf8 snf8 hypk hypk gtf2h3 gtf2h3 cfap36 cfap36 alg2 alg2 daxx daxx syngr3b syngr3b mecp2 mecp2 smarce1 smarce1 rnd2 rnd2 morf4l1 morf4l1 thap7 thap7 pex14 pex14 ercc2 ercc2 stx5al stx5al pth1a pth1a ercc6 ercc6 tsc1b tsc1b rassf1 rassf1 arf6b arf6b bivm bivm scfd1 scfd1 sla2 sla2 ercc5 ercc5 exoc5 exoc5 men1 men1 arf6a arf6a ENSDARP00000135796 ENSDARP00000135796 gadd45ab gadd45ab chmp6a chmp6a ENSDARP00000140159 ENSDARP00000140159 dctn4 dctn4 syngr2b syngr2b syngr1b syngr1b mau2 mau2 chmp6b chmp6b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fez1Fasciculation and Elongation protein zeta 1 (Zygin I). (394 aa)
nfe2Nuclear factor, erythroid 2. (466 aa)
syngr1aSynaptogyrin. (223 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
atmNon-specific serine/threonine protein kinase. (3091 aa)
ercc4Excision repair cross-complementation group 4. (886 aa)
exoc4Exocyst complex component 4. (968 aa)
syngr3aSynaptogyrin. (228 aa)
mnat1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
stx5aSyntaxin 5A; Belongs to the syntaxin family. (302 aa)
tsc1aTSC complex subunit 1a. (1128 aa)
pex19Peroxisomal biogenesis factor 19. (288 aa)
hax1HCLS1-associated protein X-1. (286 aa)
id1Inhibitor of DNA-binding 1, HLH protein. (128 aa)
alox5apArachidonate 5-lipoxygenase-activating protein. (156 aa)
exoc2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (918 aa)
snf8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity). (258 aa)
hypkHuntingtin-interacting protein K. (121 aa)
gtf2h3General transcription factor IIH, polypeptide 3. (296 aa)
cfap36Cilia- and flagella-associated protein 36; Belongs to the CFAP36 family. (350 aa)
alg2ALG2 alpha-1,3/1,6-mannosyltransferase. (455 aa)
daxxDeath-domain-associated protein. (716 aa)
syngr3bSynaptogyrin. (233 aa)
mecp2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (524 aa)
smarce1SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily e, member 1. (420 aa)
rnd2Rho family GTPase 2. (234 aa)
morf4l1Mortality factor 4-like 1. (323 aa)
thap7THAP domain-containing 7. (627 aa)
pex14Peroxisomal biogenesis factor 14. (423 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
stx5alSyntaxin 5A,-like. (347 aa)
pth1aParathyroid hormone 1a. (102 aa)
ercc6Excision repair cross-complementation group 6. (1389 aa)
tsc1bTSC complex subunit 1b. (1228 aa)
rassf1Ras association domain family member 1. (321 aa)
arf6bADP-ribosylation factor 6a; Belongs to the small GTPase superfamily. Arf family. (175 aa)
bivmBasic, immunoglobulin-like variable motif-containing. (502 aa)
scfd1Sec1 family domain-containing 1; Belongs to the STXBP/unc-18/SEC1 family. (632 aa)
sla2Src-like-adaptor 2. (264 aa)
ercc5Excision repair cross-complementation group 5. (1010 aa)
exoc5Exocyst complex component 5. (708 aa)
men1Multiple endocrine neoplasia I. (617 aa)
arf6aADP-ribosylation factor 6a. (175 aa)
ENSDARP00000135796Si:ch211-25d12.7. (254 aa)
gadd45abGrowth arrest and DNA-damage-inducible, alpha, b. (156 aa)
chmp6aCharged multivesicular body protein 6a. (199 aa)
ENSDARP00000140159Si:dkey-225f5.4. (378 aa)
dctn4Dynactin 4. (467 aa)
syngr2bSynaptogyrin. (235 aa)
syngr1bSynaptogyrin 1b. (196 aa)
mau2MAU2 sister chromatid cohesion factor. (564 aa)
chmp6bCharged multivesicular body protein 6; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In the ESCRT-III complex, it probably serves as an accepto [...] (206 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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