(25 nodes) Regulation of neuronal synaptic plasticity network (Danio rerio)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	syngr1a	Synaptogyrin. (223 aa)
	syap1	Synapse-associated protein 1. (334 aa)
	cln3	Battenin. (446 aa)
	nptnb	Neuroplastin b. (403 aa)
	shisa9a	Protein shisa-9A; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity). (382 aa)
	shisa9b	Protein shisa-9B; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity). (433 aa)
	s100b	S100 calcium-binding protein, beta (neural); Belongs to the S-100 family. (95 aa)
	LOC110437736	Neuropilin (NRP) and tolloid (TLL)-like 1. (523 aa)
	neto1l	Neuropilin (NRP) and tolloid (TLL)-like 1, like. (539 aa)
	syngr3b	Synaptogyrin. (233 aa)
	shisa7b	Shisa family member 7. (632 aa)
	nsmfa	NMDA receptor synaptonuclear-signaling and neuronal migration factor a. (600 aa)
	nf1b	Neurofibromin 1b. (2759 aa)
	LOC101883130	Shisa family member 7a. (355 aa)
	nf1a	Neurofibromin 1a. (2759 aa)
	X1WGX6_DANRE	Si:ch73-330k17.3. (221 aa)
	appa	Amyloid beta (A4) precursor protein a. (194 aa)
	ncdn	Neurochondrin. (702 aa)
	nsmfb	NMDA receptor synaptonuclear signaling and neuronal migration factor; Stimulates outgrowth of olfactory axons and migration of hypophysiotropic gonadotropin-releasing hormone 3 (GnRH3) neurons. May couple NMDA-sensitive glutamate receptor signaling to the nucleus and trigger long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. (570 aa)
	nptna	Zgc:162565 protein. (277 aa)
	syngr1b	Synaptogyrin 1b. (196 aa)
	LOC100535636	Uncharacterized protein. (410 aa)
	shisa8b	Shisa family member 8b. (431 aa)
	cntn2	Contactin 2. (1040 aa)
	shisa6	Uncharacterized protein. (275 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100535636	LOC101883130	ENSDARP00000143491	ENSDARP00000121902	Uncharacterized protein.	Shisa family member 7a.	0.571
LOC100535636	shisa6	ENSDARP00000143491	ENSDARP00000156461	Uncharacterized protein.	Uncharacterized protein.	0.540
LOC100535636	shisa7b	ENSDARP00000143491	ENSDARP00000114015	Uncharacterized protein.	Shisa family member 7.	0.567
LOC100535636	shisa8b	ENSDARP00000143491	ENSDARP00000143717	Uncharacterized protein.	Shisa family member 8b.	0.553
LOC100535636	shisa9a	ENSDARP00000143491	ENSDARP00000066385	Uncharacterized protein.	Protein shisa-9A; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity).	0.540
LOC100535636	shisa9b	ENSDARP00000143491	ENSDARP00000069025	Uncharacterized protein.	Protein shisa-9B; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity).	0.540
LOC101883130	LOC100535636	ENSDARP00000121902	ENSDARP00000143491	Shisa family member 7a.	Uncharacterized protein.	0.571
LOC101883130	shisa6	ENSDARP00000121902	ENSDARP00000156461	Shisa family member 7a.	Uncharacterized protein.	0.561
LOC101883130	shisa7b	ENSDARP00000121902	ENSDARP00000114015	Shisa family member 7a.	Shisa family member 7.	0.550
LOC101883130	shisa8b	ENSDARP00000121902	ENSDARP00000143717	Shisa family member 7a.	Shisa family member 8b.	0.588
LOC101883130	shisa9a	ENSDARP00000121902	ENSDARP00000066385	Shisa family member 7a.	Protein shisa-9A; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity).	0.540
LOC101883130	shisa9b	ENSDARP00000121902	ENSDARP00000069025	Shisa family member 7a.	Protein shisa-9B; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity).	0.540
appa	cntn2	ENSDARP00000130555	ENSDARP00000149940	Amyloid beta (A4) precursor protein a.	Contactin 2.	0.556
cntn2	appa	ENSDARP00000149940	ENSDARP00000130555	Contactin 2.	Amyloid beta (A4) precursor protein a.	0.556
nf1a	nf1b	ENSDARP00000128480	ENSDARP00000119608	Neurofibromin 1a.	Neurofibromin 1b.	0.901
nf1b	nf1a	ENSDARP00000119608	ENSDARP00000128480	Neurofibromin 1b.	Neurofibromin 1a.	0.901
shisa6	LOC100535636	ENSDARP00000156461	ENSDARP00000143491	Uncharacterized protein.	Uncharacterized protein.	0.540
shisa6	LOC101883130	ENSDARP00000156461	ENSDARP00000121902	Uncharacterized protein.	Shisa family member 7a.	0.561
shisa6	shisa7b	ENSDARP00000156461	ENSDARP00000114015	Uncharacterized protein.	Shisa family member 7.	0.540
shisa6	shisa8b	ENSDARP00000156461	ENSDARP00000143717	Uncharacterized protein.	Shisa family member 8b.	0.540

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