STRINGSTRING
neu3.1 neu3.1 dkk1a dkk1a drd4-rs drd4-rs bmp2k bmp2k wdr54 wdr54 magi2a magi2a picalma picalma ankrd13b ankrd13b dab2 dab2 cd63 cd63 wu:fj42b12 wu:fj42b12 SCYL2 SCYL2 unc119a unc119a grem1a grem1a notch1b notch1b drd4b drd4b gsg1l gsg1l ldlrap1b ldlrap1b ppt1 ppt1 aak1b aak1b unc119b unc119b dkk1b dkk1b vtnb vtnb vtna vtna serpine1 serpine1 ntf3 ntf3 atxn2 atxn2 ankrd13a ankrd13a clul1 clul1 ccl19a.1 ccl19a.1 hspa8 hspa8 ppp3r1b ppp3r1b pick1 pick1 lrrtm2 lrrtm2 magi2b magi2b pcsk9 pcsk9 fmr1 fmr1 LOC100332300 LOC100332300 clu clu mkln1 mkln1 ccl19b ccl19b lrpap1 lrpap1 ppp3r1a ppp3r1a B7ZDD1_DANRE B7ZDD1_DANRE lrrtm1 lrrtm1 snap91b snap91b tbc1d5 tbc1d5 ahi1 ahi1 rabgef1 rabgef1 hip1 hip1 grem2a grem2a rin3 rin3 aak1a aak1a mib1 mib1 snap91a snap91a hip1rb hip1rb picalmb picalmb adipoqb adipoqb ankrd13d ankrd13d notch1a notch1a drd4a drd4a ENSDARP00000146183 ENSDARP00000146183 ldlrap1a ldlrap1a rabgef1l rabgef1l
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
neu3.1Sialidase 3 (membrane sialidase), tandem duplicate 1. (409 aa)
dkk1aDickkopf WNT-signaling pathway inhibitor 1a. (256 aa)
drd4-rsDopamine receptor D4-related sequence; Belongs to the G-protein coupled receptor 1 family. (418 aa)
bmp2kBMP2-inducible kinase. (645 aa)
wdr54WD repeat domain 54. (339 aa)
magi2aMembrane-associated guanylate kinase, WW and PDZ domain-containing 2a. (1503 aa)
picalmaPhosphatidylinositol-binding clathrin assembly protein a. (589 aa)
ankrd13bAnkyrin repeat domain 13B. (632 aa)
dab2DAB adaptor protein 2. (589 aa)
cd63Tetraspanin. (237 aa)
wu:fj42b12Si:ch211-200p22.4. (316 aa)
SCYL2Si:ch211-244b2.1. (929 aa)
unc119aUnc-119 homolog a (C. elegans). (204 aa)
grem1aGremlin. (177 aa)
notch1bNotch receptor 1b. (2465 aa)
drd4bDopamine D4c receptor; Belongs to the G-protein coupled receptor 1 family. (382 aa)
gsg1lGerm cell-specific gene 1-like protein; As a component of the AMPAR complex, modifies AMPA receptor (AMPAR) gating. (304 aa)
ldlrap1bLow density lipoprotein receptor adaptor protein 1b. (304 aa)
ppt1Palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile). (303 aa)
aak1bAP2-associated kinase 1b. (1055 aa)
unc119bProtein unc-119 homolog B. (264 aa)
dkk1bDickkopf WNT-signaling pathway inhibitor 1b. (241 aa)
vtnbVitronectin b. (449 aa)
vtnaVitronectin a. (514 aa)
serpine1Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (392 aa)
ntf3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (243 aa)
atxn2Ataxin 2. (1112 aa)
ankrd13aAnkyrin repeat domain 13A. (623 aa)
clul1Clusterin; Belongs to the clusterin family. (466 aa)
ccl19a.1C-C motif chemokine. (119 aa)
hspa8Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...] (649 aa)
ppp3r1bProtein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b. (170 aa)
pick1Protein-interacting with prkca 1. (406 aa)
lrrtm2Leucine-rich repeat transmembrane neuronal 2. (542 aa)
magi2bMembrane-associated guanylate kinase, WW and PDZ domain-containing 2b. (1332 aa)
pcsk9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (667 aa)
fmr1FMRP translational regulator 1. (569 aa)
LOC100332300Gremlin 1a, DAN family BMP antagonist. (177 aa)
cluClusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (449 aa)
mkln1Muskelin 1, intracellular mediator-containing kelch motifs. (729 aa)
ccl19bChemokine (C-C motif) ligand 19b. (128 aa)
lrpap1Low density lipoprotein receptor-related protein-associated protein 1. (345 aa)
ppp3r1aProtein phosphatase 3, regulatory subunit B, alpha a. (170 aa)
B7ZDD1_DANRESi:ch211-200p22.4. (587 aa)
lrrtm1Leucine-rich repeat transmembrane neuronal 1. (524 aa)
snap91bSynaptosome-associated protein 91b. (545 aa)
tbc1d5TBC1 domain family, member 5. (863 aa)
ahi1Abelson helper integration site 1. (1193 aa)
rabgef1RAB guanine nucleotide exchange factor (GEF) 1. (502 aa)
hip1Huntingtin-interacting protein 1. (1046 aa)
grem2aGremlin 2, DAN family BMP antagonist a. (195 aa)
rin3Ras and Rab interactor 3. (1048 aa)
aak1aAP2-associated kinase 1a. (849 aa)
mib1E3 ubiquitin-protein ligase mib1; E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. It thereby participates in many processes regulated by the Notch signaling pathway, such as midline cell fate specification prior to germ layer formation, patterning of sensory cell differentiation in the ear, neurogenesis of the hindbrain and commitment to a secretory fate in the intesti [...] (1041 aa)
snap91aSynaptosome-associated protein 91a. (913 aa)
hip1rbHuntingtin-interacting protein 1-related b. (1065 aa)
picalmbPhosphatidylinositol-binding clathrin assembly protein b. (646 aa)
adipoqbAdiponectin, C1Q and collagen domain-containing, b. (299 aa)
ankrd13dAnkyrin repeat domain 13 family, member D. (624 aa)
notch1aNeurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] (2438 aa)
drd4aDopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (380 aa)
ENSDARP00000146183Si:ch211-204c21.1. (697 aa)
ldlrap1aLow density lipoprotein receptor adaptor protein 1a. (287 aa)
rabgef1lRAB guanine nucleotide exchange factor (GEF) 1,-like. (470 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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