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Q5TZD3_DANRE Q5TZD3_DANRE hmgcrb hmgcrb hibadha hibadha pgd pgd dhfr dhfr lbr lbr fmo5 fmo5 zgc:136493 zgc:136493 tm7sf2 tm7sf2 gmds gmds gsr gsr nos2b nos2b crym crym h6pd h6pd qdprb1 qdprb1 aspdh aspdh zgc:77439 zgc:77439 gapdhs gapdhs qdpra qdpra gapdh gapdh Q5TZD0_DANRE Q5TZD0_DANRE pora pora ndor1 ndor1 ENSDARP00000155644 ENSDARP00000155644 mtrr mtrr LOC793236 LOC793236 porb porb cryz cryz hmgcra hmgcra grhpra grhpra zgc:171517 zgc:171517 qdprb2 qdprb2 nos2a nos2a dpydb dpydb qdprb2-2 qdprb2-2 grhprb grhprb dpyda.1 dpyda.1 glyr1 glyr1 dhcr7 dhcr7 g6pd g6pd nos1 nos1 dus2 dus2 TP53I3 TP53I3 dpyda.1-2 dpyda.1-2 hibadhb hibadhb
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Q5TZD3_DANREDimethylaniline monooxygenase [N-oxide-forming]. (562 aa)
hmgcrb3-hydroxy-3-methylglutaryl coenzyme A reductase. (844 aa)
hibadha3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (328 aa)
pgd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (511 aa)
dhfrDihydrofolate reductase. (190 aa)
lbrLamin B receptor. (619 aa)
fmo5Dimethylaniline monooxygenase [N-oxide-forming]. (560 aa)
zgc:136493Zgc:136493; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (344 aa)
tm7sf2Transmembrane 7 superfamily member 2. (421 aa)
gmdsGDP-mannose 4,6 dehydratase. (370 aa)
gsrGlutathione reductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (425 aa)
nos2bNitric oxide synthase; Produces nitric oxide (NO). (1077 aa)
crymCrystallin, mu. (283 aa)
h6pdHexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). (791 aa)
qdprb1Quinoid dihydropteridine reductase b1. (239 aa)
aspdhPutative L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (276 aa)
zgc:77439Flavin-containing monooxygenase. (449 aa)
gapdhsGlyceraldehyde-3-phosphate dehydrogenase 2; Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. (335 aa)
qdpraQuinoid dihydropteridine reductase a. (237 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Also participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are proba [...] (333 aa)
Q5TZD0_DANREDimethylaniline monooxygenase [N-oxide-forming]. (543 aa)
poraNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (674 aa)
ndor1NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of ciapin1. In the N-terminal section; belongs to the flavodoxin family. (595 aa)
ENSDARP00000155644Uncharacterized protein. (116 aa)
mtrr5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (711 aa)
LOC793236Flavin-containing monooxygenase. (440 aa)
porbNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (671 aa)
cryzCrystallin, zeta (quinone reductase). (328 aa)
hmgcra3-hydroxy-3-methylglutaryl coenzyme A reductase. (884 aa)
grhpraNovel protein similar to human glyoxylate reductase/hydroxypyruvate reductase (GRHPR); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
zgc:171517Zgc:171517. (257 aa)
qdprb2Quinoid dihydropteridine reductase b2. (257 aa)
nos2aNitric oxide synthase; Produces nitric oxide (NO). (1079 aa)
dpydbDihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity); Belongs to the dihydropyrimidine dehydrogenase family. (1022 aa)
qdprb2-2Quinoid dihydropteridine reductase b2. (257 aa)
grhprbGlyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (361 aa)
dpyda.1Dihydropyrimidine dehydrogenase a, tandem duplicate 1. (237 aa)
glyr1Putative oxidoreductase GLYR1; May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of mapk14 and specifically regulating mapk14 signaling; Belongs to the HIBADH-related family. NP60 subfamily. (462 aa)
dhcr77-dehydrocholesterol reductase; Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC). (478 aa)
g6pdGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (523 aa)
nos1Nitric oxide synthase; Produces nitric oxide (NO). (1431 aa)
dus2Dihydrouridine synthase 2. (504 aa)
TP53I3Tumor protein p53 inducible protein 3. (328 aa)
dpyda.1-2Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (703 aa)
hibadhb3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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