STRINGSTRING
metrnlb metrnlb cylda cylda smpdl3b smpdl3b zgc:173709 zgc:173709 pparab pparab nlrx1 nlrx1 R4GE18_DANRE R4GE18_DANRE R4GEZ5_DANRE R4GEZ5_DANRE cyldl cyldl sharpin sharpin X1WE09_DANRE X1WE09_DANRE nr1d2a nr1d2a zgc:174944 zgc:174944 ENSDARP00000130165 ENSDARP00000130165 lrfn5a lrfn5a metrnla metrnla LOC101884563 LOC101884563 F1Q7D8_DANRE F1Q7D8_DANRE ENSDARP00000131837 ENSDARP00000131837 ENSDARP00000132542 ENSDARP00000132542 LOC108183680 LOC108183680 zgc:92162 zgc:92162 LOC101882060 LOC101882060 ENSDARP00000133576 ENSDARP00000133576 ENSDARP00000133818 ENSDARP00000133818 ENSDARP00000134072 ENSDARP00000134072 zgc:174944-3 zgc:174944-3 H0WEA7_DANRE H0WEA7_DANRE si:dkey-16p6.1-14 si:dkey-16p6.1-14 lrfn5b lrfn5b ENSDARP00000136722 ENSDARP00000136722 ENSDARP00000137135 ENSDARP00000137135 ENSDARP00000137199 ENSDARP00000137199 LOC108183940 LOC108183940 ENSDARP00000138564 ENSDARP00000138564 proca proca ENSDARP00000138756 ENSDARP00000138756 LOC108184002 LOC108184002 zgc:158343 zgc:158343 si:dkey-27n6.4 si:dkey-27n6.4 ENSDARP00000140829 ENSDARP00000140829 ENSDARP00000141204 ENSDARP00000141204 adipoqb adipoqb pparg pparg si:dkey-26m3.3 si:dkey-26m3.3 si:dkey-16p6.1-18 si:dkey-16p6.1-18 tnfaip3 tnfaip3 fndc4b fndc4b irg1l irg1l tnfaip6 tnfaip6 gpr17 gpr17 wfdc1 wfdc1 ghsra ghsra dusp10 dusp10 fndc4a fndc4a nr1h4 nr1h4 il22ra2 il22ra2 mdka mdka socs3a socs3a rb1 rb1 mvk mvk mdkb mdkb rabgef1 rabgef1 rabgef1l rabgef1l tnfrsf1a tnfrsf1a vps35 vps35 ptger4b ptger4b crfb16 crfb16 ptger4a ptger4a nt5e nt5e socs3b socs3b grnb grnb C10H5orf30 C10H5orf30 il10 il10 ptger4c ptger4c il12ba il12ba mfhas1 mfhas1 LOC100001665 LOC100001665 lpcat3 lpcat3 cdh5 cdh5 nr1d1 nr1d1 tnfrsf1b tnfrsf1b ash1l ash1l nr1h5 nr1h5 si:dkey-16p6.1 si:dkey-16p6.1 cyldb cyldb pparaa pparaa si:dkey-16p6.1-2 si:dkey-16p6.1-2 mkrn2 mkrn2 nr1d2b nr1d2b otulinb otulinb F1Q5P9_DANRE F1Q5P9_DANRE grna grna LOC560232 LOC560232 F6NUU8_DANRE F6NUU8_DANRE si:dkey-51d8.1 si:dkey-51d8.1 ENSDARP00000115194 ENSDARP00000115194 F1Q912_DANRE F1Q912_DANRE F1QPY4_DANRE F1QPY4_DANRE psmb4 psmb4 F1QLZ1_DANRE F1QLZ1_DANRE proca-2 proca-2 E9QHS4_DANRE E9QHS4_DANRE F1R571_DANRE F1R571_DANRE ghrl ghrl F1R5D8_DANRE F1R5D8_DANRE acod1 acod1 F1QGE7_DANRE F1QGE7_DANRE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metrnlbMeteorin-like, glial cell differentiation regulator b. (290 aa)
cyldaCylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (951 aa)
smpdl3bSphingomyelin phosphodiesterase acid-like 3B. (456 aa)
zgc:173709Si:dkey-156k2.3. (1310 aa)
pparabPeroxisome proliferator-activated receptor alpha b. (459 aa)
nlrx1NLR family member X1. (1005 aa)
R4GE18_DANRESi:dkey-31e10.5. (255 aa)
R4GEZ5_DANRESi:zfos-364h11.2. (1175 aa)
cyldlCylindromatosis (turban tumor syndrome),-like; Belongs to the peptidase C19 family. (761 aa)
sharpinSHANK-associated RH domain-interacting protein. (394 aa)
X1WE09_DANRESi:dkey-23k10.2. (1074 aa)
nr1d2aNuclear receptor subfamily 1, group D, member 2a. (504 aa)
zgc:174944Zgc:174944. (1180 aa)
ENSDARP00000130165Si:dkey-31n13.4. (1142 aa)
lrfn5aLeucine-rich repeat and fibronectin type III domain-containing 5a. (786 aa)
metrnlaMeteorin-like protein; Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance (By similarity); Belongs to the meteorin family. (286 aa)
LOC101884563Si:dkey-193i10.4. (1206 aa)
F1Q7D8_DANRESi:ch211-127b6.2. (1370 aa)
ENSDARP00000131837Si:dkey-279j5.1. (1301 aa)
ENSDARP00000132542Si:dkey-31e10.1. (277 aa)
LOC108183680Si:dkeyp-4c4.2. (1173 aa)
zgc:92162Phospholipase A(2). (153 aa)
LOC101882060Si:dkey-237g15.2. (1278 aa)
ENSDARP00000133576Si:ch211-227e10.3. (1158 aa)
ENSDARP00000133818Si:dkey-190j3.2. (1057 aa)
ENSDARP00000134072Cystatin domain-containing protein. (125 aa)
zgc:174944-3Zgc:174944. (1104 aa)
H0WEA7_DANRESi:dkey-56m15.2. (1260 aa)
si:dkey-16p6.1-14Si:dkey-16p6.1. (1234 aa)
lrfn5bLeucine-rich repeat and fibronectin type III domain-containing 5b. (765 aa)
ENSDARP00000136722Si:dkeyp-35e5.5. (1232 aa)
ENSDARP00000137135Si:ch211-196f19.1. (1052 aa)
ENSDARP00000137199Si:dkey-165o8.2. (1233 aa)
LOC108183940Si:ch211-258f1.3. (1229 aa)
ENSDARP00000138564Si:ch211-268b14.2. (1144 aa)
procaProtein C (inactivator of coagulation factors Va and VIIIa), a. (434 aa)
ENSDARP00000138756Si:ch211-223g7.6. (1057 aa)
LOC108184002Si:dkey-14o6.1. (1238 aa)
zgc:158343Zgc:158343. (208 aa)
si:dkey-27n6.4Si:dkey-27n6.4. (1304 aa)
ENSDARP00000140829Si:dkey-261j11.2. (1223 aa)
ENSDARP00000141204Si:dkey-22a18.2. (1290 aa)
adipoqbAdiponectin, C1Q and collagen domain-containing, b. (299 aa)
ppargPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (116 aa)
si:dkey-26m3.3Si:dkey-26m3.3. (1220 aa)
si:dkey-16p6.1-18Si:dkey-16p6.1. (1205 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (756 aa)
fndc4bFibronectin type III domain-containing 4b. (233 aa)
irg1lImmunoresponsive gene 1,-like. (498 aa)
tnfaip6Tumor necrosis factor, alpha-induced protein 6. (271 aa)
gpr17G_PROTEIN_RECEP_F1_2 domain-containing protein. (339 aa)
wfdc1WAP four-disulfide core domain 1. (220 aa)
ghsraGrowth hormone secretagogue receptor a; Belongs to the G-protein coupled receptor 1 family. (360 aa)
dusp10Dual-specificity phosphatase 10. (459 aa)
fndc4aFibronectin type III domain-containing 4a. (220 aa)
nr1h4Nuclear receptor subfamily 1, group H, member 4. (483 aa)
il22ra2Interleukin 22 receptor, alpha 2. (238 aa)
mdkaMidkine-related growth factor Mdk1. (146 aa)
socs3aSuppressor of cytokine-signaling 3a. (207 aa)
rb1Retinoblastoma 1. (903 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)
mdkbMidkine-related growth factor Mdk2. (147 aa)
rabgef1RAB guanine nucleotide exchange factor (GEF) 1. (502 aa)
rabgef1lRAB guanine nucleotide exchange factor (GEF) 1,-like. (470 aa)
tnfrsf1aTumor necrosis factor receptor superfamily, member 1a. (389 aa)
vps35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (831 aa)
ptger4bProstaglandin E receptor 4 (subtype EP4) b; Belongs to the G-protein coupled receptor 1 family. (497 aa)
crfb16Cytokine receptor family member B16. (300 aa)
ptger4aProstaglandin E receptor 4 (subtype EP4) a; Belongs to the G-protein coupled receptor 1 family. (403 aa)
nt5e5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. (571 aa)
socs3bSuppressor of cytokine-signaling 3b. (210 aa)
grnbGranulin b. (729 aa)
C10H5orf30Macrophage immunometabolism regulator; May play a role in immune regulation through regulation of the macrophage function (By similarity). Involved in the recruitment of macrophages in response to injury. May also play a role in trafficking of proteins via its interaction with unc119 family cargo adapters (By similarity). May play a role in ciliary membrane localization. (206 aa)
il10Interleukin-10. (180 aa)
ptger4cProstaglandin E receptor 4 (subtype EP4) c; Belongs to the G-protein coupled receptor 1 family. (435 aa)
il12baInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (350 aa)
mfhas1Malignant fibrous histiocytoma-amplified sequence 1. (992 aa)
LOC100001665OTU deubiquitinase with linear linkage-specificity a. (858 aa)
lpcat3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (465 aa)
cdh5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (767 aa)
nr1d1Nuclear receptor subfamily 1, group d, member 1. (637 aa)
tnfrsf1bTumor necrosis factor receptor superfamily, member 1B. (425 aa)
ash1lAsh1 (absent, small, or homeotic)-like (Drosophila). (2962 aa)
nr1h5Nuclear receptor subfamily 1, group H, member 5. (486 aa)
si:dkey-16p6.1Si:dkey-16p6.1. (1205 aa)
cyldbCylindromatosis (turban tumor syndrome), b. (694 aa)
pparaaPeroxisome proliferator-activated receptor alpha a. (470 aa)
si:dkey-16p6.1-2Si:dkey-16p6.1. (1220 aa)
mkrn2Probable E3 ubiquitin-protein ligase makorin-2; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Inhibits neurogenesis and axis formation during embryonic development by modulating the phosphatidylinositol 3-kinase (PI3K) pathway. Acts downstream of PI3K and akt1 to up-regulate gsk3b mRNA expression. (414 aa)
nr1d2bNuclear receptor subfamily 1, group D, member 2b. (578 aa)
otulinbOTU deubiquitinase with linear linkage-specificity b. (409 aa)
F1Q5P9_DANRESi:ch211-214b16.4. (1489 aa)
grnaGranulin a. (1049 aa)
LOC560232Si:ch211-22k7.9. (1205 aa)
F6NUU8_DANRESi:dkey-196n19.2. (1166 aa)
si:dkey-51d8.1Si:dkey-51d8.1. (1218 aa)
ENSDARP00000115194Si:ch211-22k7.9. (1232 aa)
F1Q912_DANRESi:dkey-261p22.1. (1179 aa)
F1QPY4_DANRESi:ch211-214b16.3. (1330 aa)
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (256 aa)
F1QLZ1_DANRESi:ch211-226o13.1. (1145 aa)
proca-2Protein C (inactivator of coagulation factors Va and VIIIa), a. (434 aa)
E9QHS4_DANRESi:dkey-175m17.7. (892 aa)
F1R571_DANRESi:dkey-13n15.11. (1319 aa)
ghrlGhrelin/obestatin prepropeptide. (104 aa)
F1R5D8_DANRESi:ch211-76m11.5. (1162 aa)
acod1Aconitate decarboxylase 1. (477 aa)
F1QGE7_DANRESi:ch211-196h16.4. (1057 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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