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hsp90b1 hsp90b1 dkk1a dkk1a dab2 dab2 ldlrap1b ldlrap1b apoeb apoeb apoba apoba cltca cltca dkk1b dkk1b pcsk9 pcsk9 cltcl1 cltcl1 lrpap1 lrpap1 cltcb cltcb ankra2 ankra2 ap2a1 ap2a1 apoea apoea mesd mesd ENSDARP00000146183 ENSDARP00000146183
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hsp90b1Heat shock protein 90, beta (Grp94), member 1. (793 aa)
dkk1aDickkopf WNT-signaling pathway inhibitor 1a. (256 aa)
dab2DAB adaptor protein 2. (589 aa)
ldlrap1bLow density lipoprotein receptor adaptor protein 1b. (304 aa)
apoebApolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. (281 aa)
apobaApolipoprotein Ba. (4418 aa)
cltcaClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1680 aa)
dkk1bDickkopf WNT-signaling pathway inhibitor 1b. (241 aa)
pcsk9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (667 aa)
cltcl1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1638 aa)
lrpap1Low density lipoprotein receptor-related protein-associated protein 1. (345 aa)
cltcbClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1677 aa)
ankra2Ankyrin repeat, family A (RFXANK-like), 2. (301 aa)
ap2a1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (959 aa)
apoeaApolipoprotein Ea. (269 aa)
mesdLRP chaperone MESD; Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway (By similarity). Belongs to the MESD family. (206 aa)
ENSDARP00000146183Si:ch211-204c21.1. (697 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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