(53 nodes) Negative regulation of T cell activation network (Danio rerio)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	LOC798191	Si:dkey-23c22.7. (234 aa)
	mcm6l	DNA helicase; Belongs to the MCM family. (824 aa)
	tbx21	T-box transcription factor 21. (609 aa)
	mdkb	Midkine-related growth factor Mdk2. (147 aa)
	fgl2a	Fibrinogen-like 2a. (451 aa)
	tnfrsf21	Tumor necrosis factor receptor superfamily, member 21. (637 aa)
	mdka	Midkine-related growth factor Mdk1. (146 aa)
	socs1a	Suppressor of cytokine-signaling 1a. (201 aa)
	arg2	Arginase. (347 aa)
	lrrc32	Leucine-rich repeat-containing 32. (659 aa)
	lgals9l3	Galectin. (320 aa)
	tgfb1a	Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
	cebpb	CCAAT/enhancer-binding protein. (280 aa)
	pawr	PRKC, apoptosis, WT1, regulator like. (305 aa)
	glmna	Glomulin, FKBP-associated protein a. (592 aa)
	sdc4	Syndecan 4. (207 aa)
	E7FCG4_DANRE	Si:ch211-157b11.8. (392 aa)
	ripor2	Rho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization (By similarity). Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation. Maintains naive T lymphocytes in a quiescent state and prevents chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis an [...] (1083 aa)
	gpnmb	Glycoprotein (transmembrane) nmb. (627 aa)
	rc3h2	Ring finger and CCCH-type domains 2. (1028 aa)
	vsir	V-set immunoregulatory receptor. (275 aa)
	crfb16	Cytokine receptor family member B16. (300 aa)
	lgals9l1	Galectin. (310 aa)
	dlg5a	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1926 aa)
	arg1	Arginase. (341 aa)
	dlg5b.1	Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family. (1888 aa)
	vtcn1	V-set domain-containing T cell activation inhibitor 1. (268 aa)
	loxl3b	Lysyl oxidase homolog 3B; Protein-lysine 6-oxidase that mediates the oxidation of peptidyl lysine residues to allysine in target proteins (By similarity). Catalyzes the post-translational oxidative deamination of peptidyl lysine residues in precursors of elastin and different types of collagens, a prerequisite in the formation of cross-links between collagens and elastin (By similarity). Can mediate oxidation of lysine residues that are acetylated (By similarity). Also able to catalyze deacetylation of lysine residues (By similarity). Required for maturation of neural crest derived car [...] (807 aa)
	crtam	Ig-like domain-containing protein. (436 aa)
	hlx1	H2.0-like homeo box 1 (Drosophila). (356 aa)
	tmem131l	Transmembrane 131-like. (1545 aa)
	ripor3	RIPOR family member 3; Belongs to the RIPOR family. (997 aa)
	zgc:153759	Zgc:153759. (266 aa)
	pag1	Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (405 aa)
	rc3h1b	Ring finger and CCCH-type domains 1b. (1098 aa)
	tgfb1b	Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
	F1QSM4_DANRE	Si:ch211-203k16.3. (425 aa)
	zgc:153759-2	Zgc:153759. (285 aa)
	mad1l1	Mitotic arrest deficient-like protein 1. (717 aa)
	zc3h12a	Zinc finger CCCH-type-containing 12A. (367 aa)
	march7	Membrane-associated ring finger (C3HC4) 7. (768 aa)
	loxl3a	Lysyl oxidase homolog 3A; Protein-lysine 6-oxidase that mediates the oxidation of peptidyl lysine residues to allysine in target proteins. Catalyzes the post-translational oxidative deamination of peptidyl lysine residues in precursors of elastin and different types of collagens, a prerequisite in the formation of cross-links between collagens and elastin. Can mediate oxidation of lysine residues that are acetylated. Also able to catalyze deacetylation of lysine residues (By similarity). (791 aa)
	itcha	E3 ubiquitin-protein ligase. (851 aa)
	itchb	E3 ubiquitin-protein ligase. (842 aa)
	ENSDARP00000134264	Si:ch211-241b2.5. (465 aa)
	B8JJU9_DANRE	Si:dkey-206d17.12. (626 aa)
	irf1b	Interferon regulatory factor. (287 aa)
	fgl1	Fibrinogen-like 1. (307 aa)
	cbfb	Core-binding factor subunit beta. (201 aa)
	ENSDARP00000148959	Si:dkey-23c22.5. (239 aa)
	ENSDARP00000150473	Si:ch211-261n11.7. (348 aa)
	rc3h1a	Ring finger and CCCH-type domains 1a. (1111 aa)
	march7-2	Membrane-associated ring finger (C3HC4) 7. (179 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSDARP00000134264	lgals9l1	ENSDARP00000134264	ENSDARP00000090918	Si:ch211-241b2.5.	Galectin.	0.419
ENSDARP00000134264	lgals9l3	ENSDARP00000134264	ENSDARP00000060156	Si:ch211-241b2.5.	Galectin.	0.419
ENSDARP00000134264	vtcn1	ENSDARP00000134264	ENSDARP00000101000	Si:ch211-241b2.5.	V-set domain-containing T cell activation inhibitor 1.	0.594
LOC798191	zgc:153759	ENSDARP00000146645	ENSDARP00000119676	Si:dkey-23c22.7.	Zgc:153759.	0.901
arg1	arg2	ENSDARP00000097045	ENSDARP00000057376	Arginase.	Arginase.	0.906
arg2	arg1	ENSDARP00000057376	ENSDARP00000097045	Arginase.	Arginase.	0.906
cbfb	cebpb	ENSDARP00000142460	ENSDARP00000062701	Core-binding factor subunit beta.	CCAAT/enhancer-binding protein.	0.630
cbfb	tgfb1a	ENSDARP00000142460	ENSDARP00000060838	Core-binding factor subunit beta.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.406
cebpb	cbfb	ENSDARP00000062701	ENSDARP00000142460	CCAAT/enhancer-binding protein.	Core-binding factor subunit beta.	0.630
cebpb	irf1b	ENSDARP00000062701	ENSDARP00000140878	CCAAT/enhancer-binding protein.	Interferon regulatory factor.	0.494
gpnmb	sdc4	ENSDARP00000085316	ENSDARP00000078265	Glycoprotein (transmembrane) nmb.	Syndecan 4.	0.557
hlx1	tbx21	ENSDARP00000116160	ENSDARP00000006762	H2.0-like homeo box 1 (Drosophila).	T-box transcription factor 21.	0.574
irf1b	cebpb	ENSDARP00000140878	ENSDARP00000062701	Interferon regulatory factor.	CCAAT/enhancer-binding protein.	0.494
irf1b	socs1a	ENSDARP00000140878	ENSDARP00000055536	Interferon regulatory factor.	Suppressor of cytokine-signaling 1a.	0.723
itcha	itchb	ENSDARP00000128218	ENSDARP00000130100	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.901
itchb	itcha	ENSDARP00000130100	ENSDARP00000128218	E3 ubiquitin-protein ligase.	E3 ubiquitin-protein ligase.	0.901
lgals9l1	ENSDARP00000134264	ENSDARP00000090918	ENSDARP00000134264	Galectin.	Si:ch211-241b2.5.	0.419
lgals9l3	ENSDARP00000134264	ENSDARP00000060156	ENSDARP00000134264	Galectin.	Si:ch211-241b2.5.	0.419
lrrc32	tgfb1a	ENSDARP00000059477	ENSDARP00000060838	Leucine-rich repeat-containing 32.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.866
lrrc32	tgfb1b	ENSDARP00000059477	ENSDARP00000122056	Leucine-rich repeat-containing 32.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.866

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