STRINGSTRING
dnmt1 dnmt1 ctr9 ctr9 mcrs1 mcrs1 prdm9 prdm9 phf20b phf20b myb myb kdm1a kdm1a nelfa nelfa smad4a smad4a gb:cr929477 gb:cr929477 kansl2 kansl2 prmt6 prmt6 auts2a auts2a rtf1 rtf1 phf20a phf20a kansl1a kansl1a kmt2e kmt2e fbrsl1 fbrsl1 pygo2 pygo2 Q1L8R8_DANRE Q1L8R8_DANRE E7FFZ5_DANRE E7FFZ5_DANRE kansl1b kansl1b auts2b auts2b ogt.1 ogt.1 snw1 snw1 ogt.2 ogt.2 ZNF335 ZNF335 kansl1l kansl1l
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnmt1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1500 aa)
ctr9CTR9 homolog, Paf1/RNA polymerase II complex component. (1160 aa)
mcrs1Microspherule protein 1. (472 aa)
prdm9Histone-lysine N-methyltransferase PRDM9; Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4) and 'Lys-36' (H3K36) of histone H3 to produce respectively trimethylated 'Lys-4' (H3K4me3) and trimethylated 'Lys-36' (H3K36me3) histone H3 and plays a key role in meiotic prophase by determining hotspot localization thereby promoting meiotic recombination. Also can methylate all four core histones with H3 being the best substrate and the most highly modified. Is also able, on one hand, to mono and di-methylate H4K20 and on other hand to trimethylate [...] (853 aa)
phf20bPHD finger protein 20, b. (986 aa)
mybV-myb avian myeloblastosis viral oncogene homolog. (641 aa)
kdm1aLysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (833 aa)
nelfaNegative elongation factor complex member A. (542 aa)
smad4aMothers against decapentaplegic homolog. (547 aa)
gb:cr929477SMAD family member 4. (332 aa)
kansl2KAT8 regulatory NSL complex subunit 2. (408 aa)
prmt6Protein arginine N-methyltransferase 6; Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays preference for monomethylated substrates. Specifically mediates the asymmetric dimethylation of histone H3 'Arg-2' to form H3R2me2a. H3R2me2a represents a specific tag for epigenetic transcriptional repression and is mutually exclusive with methylation on [...] (355 aa)
auts2aActivator of transcription and developmental regulator AUTS2 a. (1278 aa)
rtf1RTF1 homolog, Paf1/RNA polymerase II complex component. (701 aa)
phf20aPHD finger protein 20, a. (932 aa)
kansl1aKAT8 regulatory NSL complex subunit 1a. (1022 aa)
kmt2eLysine (K)-specific methyltransferase 2E. (1265 aa)
fbrsl1Fibrosin-like 1. (867 aa)
pygo2Pygopus homolog 2 (Drosophila). (571 aa)
Q1L8R8_DANREMothers against decapentaplegic homolog. (571 aa)
E7FFZ5_DANREMothers against decapentaplegic homolog. (568 aa)
kansl1bKAT8 regulatory NSL complex subunit 1b. (1037 aa)
auts2bActivator of transcription and developmental regulator AUTS2 b. (748 aa)
ogt.1O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1062 aa)
snw1SNW domain-containing 1. (536 aa)
ogt.2O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1102 aa)
ZNF335Si:ch211-269m15.3. (1534 aa)
kansl1lKAT8 regulatory NSL complex subunit 1-like. (809 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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