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chrna5 chrna5 gabrr1 gabrr1 p2rx2 p2rx2 gabra4 gabra4 gabrr2b gabrr2b glra3 glra3 chrnd chrnd chrna1 chrna1 chrna4b chrna4b p2rx5 p2rx5 glra4b glra4b chrna2a chrna2a glra4a glra4a chrnb1l chrnb1l chrna6 chrna6 p2rx8 p2rx8 chrnb2 chrnb2 E7F1T1_DANRE E7F1T1_DANRE GRIN2B GRIN2B glra1 glra1 gabrr3a gabrr3a chrnb3b chrnb3b gabra6a gabra6a p2rx7 p2rx7 npffl npffl chrnb3a chrnb3a glrbb glrbb gabrp gabrp gabrr2a gabrr2a gabrz gabrz npas4a npas4a cdk5 cdk5 gabra2a gabra2a gabrb3 gabrb3 gabrg2 gabrg2 p2rx4b p2rx4b chrnb1 chrnb1 glrba glrba grin2ab grin2ab LOC100149482 LOC100149482 glra2 glra2 F1QTM9_DANRE F1QTM9_DANRE gabrb1 gabrb1 gabrb2a gabrb2a p2rx4a p2rx4a gabra6b gabra6b mecp2 mecp2 chrng chrng grin2ca grin2ca grin2bb grin2bb npas4b npas4b gabrd gabrd chrne chrne grin2aa grin2aa gabra5 gabra5 p2rx3b p2rx3b chrna2b chrna2b ghrl ghrl Chrna11 Chrna11 chrna10a chrna10a grin2cb grin2cb LOC100334841 LOC100334841 chrna3 chrna3 GABRR1 GABRR1 gabra1 gabra1 LOC561083 LOC561083 gabrg1 gabrg1 gabrb4 gabrb4 chrnb4 chrnb4 LOC798522 LOC798522 chrna7 chrna7 LOC101882451 LOC101882451 GABRB2 GABRB2 chrnb5b chrnb5b LOC101882637 LOC101882637 ENSDARP00000144302 ENSDARP00000144302 LOC101885452 LOC101885452 chrnb5a chrnb5a grin2da grin2da LOC562831 LOC562831 LOC101885757 LOC101885757 p2rx1 p2rx1 ENSDARP00000153861 ENSDARP00000153861 chrna9 chrna9 ENSDARP00000157455 ENSDARP00000157455
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chrna5Cholinergic receptor, nicotinic, alpha 5. (466 aa)
gabrr1Gamma-aminobutyric acid (GABA) A receptor, rho 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (466 aa)
p2rx2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (400 aa)
gabra4Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (557 aa)
gabrr2bGamma-aminobutyric acid (GABA) A receptor, rho 2b; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
glra3Glycine receptor, alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (450 aa)
chrndCholinergic receptor, nicotinic, delta (muscle). (518 aa)
chrna1Acetylcholine receptor subunit alpha; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. (456 aa)
chrna4bNeuronal nicotinic acetylcholine receptor alpha 4 subunit. (627 aa)
p2rx5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (480 aa)
glra4bGlycine receptor, alpha 4b; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (537 aa)
chrna2aCholinergic receptor, nicotinic, alpha 2a (neuronal). (520 aa)
glra4aGlycine receptor, alpha 4a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
chrnb1lCholinergic receptor, nicotinic, beta 1 (muscle)-like. (486 aa)
chrna6Cholinergic receptor, nicotinic, alpha 6. (512 aa)
p2rx8P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (391 aa)
chrnb2Cholinergic receptor, nicotinic, beta 2. (543 aa)
E7F1T1_DANREGamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (195 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1454 aa)
glra1Glycine receptor subunit alphaZ1; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents. Channel activity is potentiated by ethanol (By similarity); Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily. GLRA1 sub-subfamily. (459 aa)
gabrr3aGamma-aminobutyric acid (GABA) A receptor, rho 3a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (472 aa)
chrnb3bCholinergic receptor, nicotinic, beta polypeptide 3b. (462 aa)
gabra6aGamma-aminobutyric acid (GABA) A receptor, alpha 6a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (395 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa)
npfflNeuropeptide FF-amide peptide precursor-like. (128 aa)
chrnb3aCholinergic receptor, nicotinic, beta polypeptide 3a. (467 aa)
glrbbGlycine receptor beta subunit 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (494 aa)
gabrpGamma-aminobutyric acid (GABA) A receptor, pi; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
gabrr2aGamma-aminobutyric acid (GABA) A receptor, rho 2a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (371 aa)
gabrzGamma-aminobutyric acid (GABA) A receptor, zeta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (447 aa)
npas4aNeuronal PAS domain-containing protein 4A; Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contextual memory in the hyppocampus. Plays a key role in the structural and functional plasticity of neurons. Acts as an early-response transcription factor in both excitatory and inhibitory neurons, where it induces distinct but overlapping sets of late- response genes in these two types of neurons, allowing the synapses that form on inhibitory and excitatory neurons to be modified by neuronal act [...] (933 aa)
cdk5Cyclin-dependent protein kinase 5; Belongs to the protein kinase superfamily. (292 aa)
gabra2aGamma-aminobutyric acid type A receptor alpha2 subunit a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
gabrb3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (532 aa)
gabrg2Gamma-aminobutyric acid (GABA) A receptor, gamma 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (477 aa)
p2rx4bP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (394 aa)
chrnb1Cholinergic receptor, nicotinic, beta 1 (muscle). (492 aa)
glrbaGlycine receptor betaZ subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (498 aa)
grin2abGlutamate receptor, ionotropic, N-methyl D-aspartate 2A, b. (1445 aa)
LOC100149482Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1676 aa)
glra2Glycine receptor, alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (449 aa)
F1QTM9_DANREUncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (345 aa)
gabrb1Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (484 aa)
gabrb2aGamma-aminobutyric acid type A receptor beta2 subunit a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (436 aa)
p2rx4aP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (398 aa)
gabra6bGamma-aminobutyric acid (GABA) A receptor, alpha 6b; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (444 aa)
mecp2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (524 aa)
chrngCholinergic receptor, nicotinic, gamma. (540 aa)
grin2caGlutamate receptor, ionotropic, N-methyl D-aspartate 2Ca. (1400 aa)
grin2bbGlutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b. (1770 aa)
npas4bNeuronal PAS domain-containing protein 4B; Transcription factor expressed in neurons of the brain that regulates the excitatory-inhibitory balance within neural circuits and is required for contextual memory in the hyppocampus. Plays a key role in the structural and functional plasticity of neurons. Acts as an early-response transcription factor in both excitatory and inhibitory neurons, where it induces distinct but overlapping sets of late- response genes in these two types of neurons, allowing the synapses that form on inhibitory and excitatory neurons to be modified by neuronal act [...] (538 aa)
gabrdGamma-aminobutyric acid (GABA) A receptor, delta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (438 aa)
chrneCholinergic receptor, nicotinic, epsilon. (517 aa)
grin2aaGlutamate receptor, ionotropic, N-methyl D-aspartate 2A, a. (1460 aa)
gabra5Gamma-aminobutyric acid (GABA) A receptor, alpha 5; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
p2rx3bP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (412 aa)
chrna2bCholinergic receptor, nicotinic, alpha 2b (neuronal). (550 aa)
ghrlGhrelin/obestatin prepropeptide. (104 aa)
Chrna11Si:ch211-39a7.1. (589 aa)
chrna10aCholinergic receptor, nicotinic, alpha 10a. (532 aa)
grin2cbUncharacterized protein. (1328 aa)
LOC100334841Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
chrna3Cholinergic receptor, nicotinic, alpha 3. (543 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (475 aa)
gabra1Gamma-aminobutyric acid (GABA) A receptor, alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (459 aa)
LOC561083Gamma-aminobutyric acid (GABA) A receptor, rho 3b; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
gabrg1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (459 aa)
gabrb4Gamma-aminobutyric acid type A receptor beta4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
chrnb4Cholinergic receptor, nicotinic, beta 4 (neuronal). (525 aa)
LOC798522Uncharacterized protein. (478 aa)
chrna7Cholinergic receptor, nicotinic, alpha 7 (neuronal). (510 aa)
LOC101882451Uncharacterized protein. (545 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (504 aa)
chrnb5bCholinergic receptor, nicotinic, beta 5b. (475 aa)
LOC101882637Uncharacterized protein. (507 aa)
ENSDARP00000144302Si:ch73-380n15.2. (509 aa)
LOC101885452Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (418 aa)
chrnb5aCholinergic receptor, nicotinic, beta 5a. (494 aa)
grin2daGlutamate receptor, ionotropic, N-methyl D-aspartate 2D, a. (1916 aa)
LOC562831Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (451 aa)
LOC101885757Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (442 aa)
p2rx1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ENSDARP00000153861Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (469 aa)
chrna9Cholinergic receptor, nicotinic, alpha 9. (580 aa)
ENSDARP00000157455Uncharacterized protein. (91 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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