STRINGSTRING
med14 med14 paxip1 paxip1 sub1a sub1a ercc6 ercc6 taf6 taf6 gtf2a1 gtf2a1 nkx2.5 nkx2.5 dhx36 dhx36 sub1b sub1b ercc1 ercc1 psmc6 psmc6 taf4b taf4b taf3 taf3 gtf2a2 gtf2a2 srfa srfa taf10 taf10 taf13 taf13 E7FFQ2_DANRE E7FFQ2_DANRE taf4a taf4a taf12 taf12 srfb srfb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
med14Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1451 aa)
paxip1PAX-interacting protein 1; Involved in DNA damage response. May function as transcriptional cofactor in TGF beta signaling. Accentuates Smad2- dependent transcription (By similarity). (1122 aa)
sub1aSUB1 regulator of transcription a. (123 aa)
ercc6Excision repair cross-complementation group 6. (1389 aa)
taf6TAF6 RNA polymerase II, TATA box-binding protein (TBP)-associated factor. (636 aa)
gtf2a1General transcription factor IIA, 1. (369 aa)
nkx2.5NK2 homeobox 5. (314 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1037 aa)
sub1bSUB1 regulator of transcription b. (124 aa)
ercc1Excision repair cross-complementing rodent repair deficiency, complementation group 1. (342 aa)
psmc6Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family. (389 aa)
taf4bTAF4B RNA polymerase II, TATA box-binding protein (TBP)-associated factor. (833 aa)
taf3TAF3 RNA polymerase II, TATA box-binding protein (TBP)-associated facto. (898 aa)
gtf2a2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
srfaSerum response factor a. (539 aa)
taf10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (181 aa)
taf13TATA-box-binding protein-associated factor 13. (124 aa)
E7FFQ2_DANRESi:dkey-219c3.2. (976 aa)
taf4aTAF4A RNA polymerase II, TATA box-binding protein (TBP)-associated factor. (821 aa)
taf12TAF12 RNA polymerase II, TATA box-binding protein (TBP)-associated factor. (162 aa)
srfbSerum response factor b. (260 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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