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srfa srfa dag1 dag1 tgfbr2b tgfbr2b wnt2bb wnt2bb tcf21 tcf21 ctsh ctsh ctsz ctsz tgfbr2a tgfbr2a hhip hhip wnt2ba wnt2ba dlg5a dlg5a dlg5b.1 dlg5b.1 hps1 hps1 stk40 stk40 srfb srfb spry1 spry1 LOC100333521 LOC100333521 ENSDARP00000148508 ENSDARP00000148508
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
srfaSerum response factor a. (539 aa)
dag1Dystroglycan 1. (866 aa)
tgfbr2bTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (556 aa)
wnt2bbProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (396 aa)
tcf21Transcription factor 21; Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. (176 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (330 aa)
ctszCathepsin Z; Belongs to the peptidase C1 family. (301 aa)
tgfbr2aSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (645 aa)
hhipHedgehog-interacting protein. (693 aa)
wnt2baProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa)
dlg5aDiscs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1926 aa)
dlg5b.1Discs, large homolog 5b (Drosophila), tandem duplicate 1; Belongs to the MAGUK family. (1888 aa)
hps1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (668 aa)
stk40Serine/threonine kinase 40. (436 aa)
srfbSerum response factor b. (260 aa)
spry1Sprouty homolog 1, antagonist of FGF-signaling (Drosophila). (292 aa)
LOC100333521Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (303 aa)
ENSDARP00000148508ecTbetaR2 domain-containing protein. (382 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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