(16 nodes) Regulation of androgen receptor signaling pathway network (Danio rerio)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dab2	DAB adaptor protein 2. (589 aa)
	rnf14	RBR-type E3 ubiquitin transferase. (459 aa)
	ncor2	Nuclear receptor corepressor 2. (2315 aa)
	tcf21	Transcription factor 21; Involved in epithelial-mesenchymal interactions in kidney and lung morphogenesis that include epithelial differentiation and branching morphogenesis. (176 aa)
	phb	Prohibitin. (271 aa)
	prmt2	Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (407 aa)
	sirt1	Sirtuin 1. (710 aa)
	rnf6	Ring finger protein (C3H2C3 type) 6. (734 aa)
	LOC558876	RBR-type E3 ubiquitin transferase. (436 aa)
	LOC110437942	RBR-type E3 ubiquitin transferase. (397 aa)
	ncor1	Nuclear receptor corepressor 1. (2398 aa)
	ep300b	E1A-binding protein p300 b. (2615 aa)
	ep300a	E1A-binding protein p300 a. (2679 aa)
	ENSDARP00000146183	Si:ch211-204c21.1. (697 aa)
	msc	Musculin (activated B-cell factor-1). (160 aa)
	ENSDARP00000156746	RBR-type E3 ubiquitin transferase. (304 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ep300a	ncor1	ENSDARP00000140048	ENSDARP00000120166	E1A-binding protein p300 a.	Nuclear receptor corepressor 1.	0.450
ep300a	rnf14	ENSDARP00000140048	ENSDARP00000017558	E1A-binding protein p300 a.	RBR-type E3 ubiquitin transferase.	0.400
ep300a	sirt1	ENSDARP00000140048	ENSDARP00000088981	E1A-binding protein p300 a.	Sirtuin 1.	0.653
ep300b	ncor1	ENSDARP00000129212	ENSDARP00000120166	E1A-binding protein p300 b.	Nuclear receptor corepressor 1.	0.450
ep300b	sirt1	ENSDARP00000129212	ENSDARP00000088981	E1A-binding protein p300 b.	Sirtuin 1.	0.651
ncor1	ep300a	ENSDARP00000120166	ENSDARP00000140048	Nuclear receptor corepressor 1.	E1A-binding protein p300 a.	0.450
ncor1	ep300b	ENSDARP00000120166	ENSDARP00000129212	Nuclear receptor corepressor 1.	E1A-binding protein p300 b.	0.450
ncor1	ncor2	ENSDARP00000120166	ENSDARP00000051138	Nuclear receptor corepressor 1.	Nuclear receptor corepressor 2.	0.666
ncor1	sirt1	ENSDARP00000120166	ENSDARP00000088981	Nuclear receptor corepressor 1.	Sirtuin 1.	0.798
ncor2	ncor1	ENSDARP00000051138	ENSDARP00000120166	Nuclear receptor corepressor 2.	Nuclear receptor corepressor 1.	0.666
ncor2	sirt1	ENSDARP00000051138	ENSDARP00000088981	Nuclear receptor corepressor 2.	Sirtuin 1.	0.753
rnf14	ep300a	ENSDARP00000017558	ENSDARP00000140048	RBR-type E3 ubiquitin transferase.	E1A-binding protein p300 a.	0.400
sirt1	ep300a	ENSDARP00000088981	ENSDARP00000140048	Sirtuin 1.	E1A-binding protein p300 a.	0.653
sirt1	ep300b	ENSDARP00000088981	ENSDARP00000129212	Sirtuin 1.	E1A-binding protein p300 b.	0.651
sirt1	ncor1	ENSDARP00000088981	ENSDARP00000120166	Sirtuin 1.	Nuclear receptor corepressor 1.	0.798
sirt1	ncor2	ENSDARP00000088981	ENSDARP00000051138	Sirtuin 1.	Nuclear receptor corepressor 2.	0.753

Server load: medium (58%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Textmining

Neighborhood

Databases

Fusion

© STRING Consortium 2025

Credits

Access

Info

About