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| | cldn5b | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | gab1 | GRB2-associated-binding protein 1. (740 aa) |
| | emd | Emerin (Emery-Dreifuss muscular dystrophy). (182 aa) |
| | LOC569566 | Fibroblast growth factor receptor 1b,-like. (509 aa) |
| | gdf7 | Growth differentiation factor 7. (396 aa) |
| | ntrk2a | Tyrosine-protein kinase receptor. (784 aa) |
| | zdhhc16a | Palmitoyltransferase ZDHHC16A; Palmitoyl acyltransferase that mediates palmitoylation of proteins and is required during embryonic heart development. Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway. (387 aa) |
| | bmp7b | Bone morphogenetic protein 7b. (427 aa) |
| | Q1L8R8_DANRE | Mothers against decapentaplegic homolog. (571 aa) |
| | zgc:56585 | Zgc:56585; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa) |
| | flrt3 | Fibronectin leucine-rich transmembrane 3. (649 aa) |
| | tgfb1b | Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa) |
| | uri1 | URI1 prefoldin-like chaperone. (512 aa) |
| | fgf7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (180 aa) |
| | fut8a | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (581 aa) |
| | mars1 | Methionyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (951 aa) |
| | rgmd | RGM domain family, member D. (458 aa) |
| | sostdc1b | Sclerostin domain-containing 1b. (204 aa) |
| | tgfb2 | Transforming growth factor, beta 2. (413 aa) |
| | setx | Senataxin. (2368 aa) |
| | fgfr2 | Fibroblast growth factor receptor 2; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in kerati [...] (838 aa) |
| | E7FFZ5_DANRE | Mothers against decapentaplegic homolog. (568 aa) |
| | usp8 | Ubiquitin-specific peptidase 8; Belongs to the peptidase C19 family. (1067 aa) |
| | flrt2 | Fibronectin leucine-rich transmembrane protein 2. (662 aa) |
| | pgfb | Placental growth factor b; Belongs to the PDGF/VEGF growth factor family. (164 aa) |
| | znf831 | Zinc finger protein 831. (1580 aa) |
| | gareml | GRB2-associated, regulator of MAPK1-like. (810 aa) |
| | akt1s1 | AKT1 substrate 1 (proline-rich). (354 aa) |
| | flrt2-2 | Fibronectin leucine-rich transmembrane protein 2. (662 aa) |
| | frs3 | Fibroblast growth factor receptor substrate 3. (627 aa) |
| | inppl1a | Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2A; Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of [...] (1003 aa) |
| | bmpr1bb | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (535 aa) |
| | phox2bb | Paired-like homeobox 2Bb. (284 aa) |
| | errfi1a | ERBB receptor feedback inhibitor 1a. (447 aa) |
| | zgc:162730 | Zgc:162730. (314 aa) |
| | fgfbp1a | Fibroblast growth factor-binding protein 1b. (197 aa) |
| | smad9 | Mothers against decapentaplegic homolog. (466 aa) |
| | clec3bb | C-type lectin domain family 3, member Bb. (200 aa) |
| | pdcd4a | Programmed cell death 4a. (467 aa) |
| | vox | Ventral homeobox. (242 aa) |
| | glg1b | Golgi glycoprotein 1b. (525 aa) |
| | fgf3 | Fibroblast growth factor 3; Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. Belongs to the heparin-binding growth factors family. (256 aa) |
| | fgf2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (154 aa) |
| | tgfbr3 | Transforming growth factor, beta receptor III. (848 aa) |
| | flt4 | Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. (1368 aa) |
| | bmper | BMP-binding endothelial regulator. (667 aa) |
| | vegfaa | Vascular endothelial growth factor A-A; Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis, and induces permeabilization of blood vessels. Acts both upstream of kdr and tie1 to stimulate endothelial cell differentiation, and upstream of gata1 to stimulate hematopoietic cell differentiation. (188 aa) |
| | LOC100331938 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa) |
| | bmp5 | Bone morphogenetic protein 5. (446 aa) |
| | nkpd1 | NTPase, KAP family P-loop domain-containing 1. (737 aa) |
| | june | JunE proto-oncogene, AP-1 transcription factor subunit. (323 aa) |
| | fgf19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | kif16ba | Kinesin family member 16Ba; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1245 aa) |
| | fgf4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa) |
| | ngfa | Neurotrophin-7; Recombinant ZNT-7 was able to bind to the human p75 neurotrophin receptor/NGFR and to induce tyrosine phosphorylation of the rat NTRK1/TRKA receptor tyrosine kinase, albeit less efficiently than rat NGF. ZNT-7 did not interact with rat NTRK2/TRKB or NTRK3/TRKC, indicating a similar receptor specificity as NGF; Belongs to the NGF-beta family. (233 aa) |
| | E7EY00_DANRE | Si:dkey-16l2.16. (209 aa) |
| | hivep1 | HIVEP zinc finger 1. (2634 aa) |
| | shcbp1 | SHC SH2-domain-binding protein 1. (721 aa) |
| | gfra1b | GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family. (481 aa) |
| | fgf17 | Fibroblast growth factor 17; Involved in dorsal-ventral embryonic patterning, by promoting expression of bone morphogenetic protein (BMP) antagonists such as chd. Also involved in anterior-posterior neural patterning and in mesoderm induction; Belongs to the heparin-binding growth factors family. (215 aa) |
| | sox5 | SRY-box transcription factor 5. (759 aa) |
| | baiap2b | BAR/IMD domain-containing adaptor protein 2b. (401 aa) |
| | cib1 | Calcium and integrin-binding 1 (calmyrin). (188 aa) |
| | fgfrl1b | Fibroblast growth factor receptor-like 1b. (481 aa) |
| | acvr2ab | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (439 aa) |
| | bambib | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (257 aa) |
| | ntrk3a | Tyrosine-protein kinase receptor. (821 aa) |
| | fgf10b | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (191 aa) |
| | ntrk2b | Tyrosine-protein kinase receptor. (801 aa) |
| | bmpr1ba | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa) |
| | fgf21 | Fibroblast growth factor 21; Belongs to the heparin-binding growth factors family. (194 aa) |
| | nrp1a | Neuropilin-1a; Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. Regulates angiogenesis through a VEGF-dependent pathway. (923 aa) |
| | ntrk3b | Tyrosine-protein kinase receptor. (813 aa) |
| | ndr2 | Nodal-related 2. (505 aa) |
| | bmpr1ab | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (535 aa) |
| | si:dkey-1k23.3 | Si:dkey-1k23.3; Belongs to the small heat shock protein (HSP20) family. (365 aa) |
| | gas1a | Growth arrest-specific 1a. (270 aa) |
| | fgfr4 | Fibroblast growth factor receptor 4; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down- regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation o [...] (923 aa) |
| | bmp16 | Bone morphogenetic protein 16. (416 aa) |
| | ENSDARP00000146009 | CUB domain-containing protein. (101 aa) |
| | pdgfba | Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (463 aa) |
| | ENSDARP00000146183 | Si:ch211-204c21.1. (697 aa) |
| | pdgfbb | Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (483 aa) |
| | ENSDARP00000146654 | Uncharacterized protein. (96 aa) |
| | ENSDARP00000147138 | TGFb_propeptide domain-containing protein. (179 aa) |
| | msx1a | Muscle segment homeobox 1a. (233 aa) |
| | bmp10l | Bone morphogenetic protein 10,-like. (406 aa) |
| | ENSDARP00000148508 | ecTbetaR2 domain-containing protein. (382 aa) |
| | sfrp2l | Secreted frizzled-related protein 2-like. (333 aa) |
| | spint1a | Serine peptidase inhibitor, Kunitz type 1 a. (523 aa) |
| | lgmn | Legumain. (438 aa) |
| | ndnf | Neuron-derived neurotrophic factor. (585 aa) |
| | pdgfrb | Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1072 aa) |
| | itgb8 | Integrin beta; Belongs to the integrin beta chain family. (668 aa) |
| | rapgef2 | Rap guanine nucleotide exchange factor (GEF) 2. (1619 aa) |
| | ccdc142 | Coiled-coil domain-containing 142. (1024 aa) |
| | sox6 | SRY-box transcription factor 6. (816 aa) |
| | appl1 | HESX homeobox 1. (718 aa) |
| | rapgef6 | Rap guanine nucleotide exchange factor (GEF) 6. (1261 aa) |
| | fkbp8 | Peptidylprolyl isomerase. (406 aa) |
| | pdcd4b | Programmed cell death 4b. (470 aa) |
| | flt1 | Vascular endothelial growth factor receptor 1 isoform 1 precursor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1272 aa) |
| | acvr1l | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa) |
| | acvr1ba | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa) |
| | lft1 | Left-right determination factor; Belongs to the TGF-beta family. (358 aa) |
| | spint1b | Serine peptidase inhibitor, Kunitz type 1 b. (499 aa) |
| | fgf20a | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | fgf1a | Putative fibroblast growth factor 1; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with i [...] (147 aa) |
| | fkbp16 | Peptidylprolyl isomerase. (430 aa) |
| | cnpy1 | Protein canopy-1; Involved in the maintenance of the midbrain-hindbrain boundary (MHB) organizer. Contributes to a positive-feedback loop of FGF signaling in the MHB, enabling the MHB to exert its role as an organizer for the tectal and cerebellar development. (187 aa) |
| | fgf6a | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (205 aa) |
| | zfp36l1b | Zinc finger protein 36, C3H type-like 1 like. (348 aa) |
| | fgfr3 | Fibroblast growth factor receptor 3; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Phosphorylates PLCG1, CBL and FRS2. Ligand binding l [...] (819 aa) |
| | bmp2a | Bone morphogenetic protein 2a. (386 aa) |
| | fgfr1a | Fibroblast growth factor receptor 1-A; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and normal skeletogenesis. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. Phosphorylation of FRS2 triggers [...] (809 aa) |
| | itgb3a | Integrin beta; Belongs to the integrin beta chain family. (785 aa) |
| | hpgd | 15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa) |
| | bmpr1aa | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (527 aa) |
| | mapkapk2b | MAPK-activated protein kinase 2b; Belongs to the protein kinase superfamily. (397 aa) |
| | bmp7a | Bone morphogenetic protein 7a. (432 aa) |
| | gata3 | Transcription factor GATA-3. (438 aa) |
| | rgmb | Repulsive guidance molecule BMP co-receptor b. (436 aa) |
| | gclc | Glutamate-cysteine ligase, catalytic subunit. (631 aa) |
| | fgf8a | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. (210 aa) |
| | gas6 | Growth arrest-specific 6. (648 aa) |
| | ntrk1 | Tyrosine-protein kinase receptor. (797 aa) |
| | magi2a | Membrane-associated guanylate kinase, WW and PDZ domain-containing 2a. (1503 aa) |
| | mapkapk2a | Mitogen-activated protein kinase-activated protein kinase 2a; Belongs to the protein kinase superfamily. (382 aa) |
| | bmp6 | Bone morphogenetic protein 6. (417 aa) |
| | churc1 | Protein Churchill; Transcriptional activator that mediates FGF signaling during neural development. Plays a role in the regulation of cell movement. Does not bind DNA by itself (By similarity). (112 aa) |
| | gclm | Glutamate-cysteine ligase, modifier subunit. (273 aa) |
| | itgb3b | Integrin beta; Belongs to the integrin beta chain family. (790 aa) |
| | pdgfrl | Platelet-derived growth factor receptor-like. (371 aa) |
| | smad7 | Mothers against decapentaplegic homolog. (372 aa) |
| | garem | GRB2-associated and regulator of MAPK protein 1; Adapter protein that may provide a link between cell surface epidermal growth factor receptor and the MAPK/ERK signaling pathway. May promote cell proliferation (By similarity). (867 aa) |
| | itgb1bp1 | Integrin beta-1-binding protein 1. (198 aa) |
| | zfp36l1a | Zinc finger protein 36, C3H type-like 1a. (374 aa) |
| | tgfb3 | Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa) |
| | syap1 | Synapse-associated protein 1. (334 aa) |
| | rgma | Repulsive guidance molecule BMP co-receptor a. (449 aa) |
| | dab2 | DAB adaptor protein 2. (589 aa) |
| | smad1 | Mothers against decapentaplegic homolog 1; Involved in ventralization. May mediate Bmp2b signaling during embryonic dorsal-ventral pattern formation, and may itself be a transcriptional target for Smad5-mediated Bmp2b signaling. Belongs to the dwarfin/SMAD family. (472 aa) |
| | pdcd5 | Programmed cell death 5. (128 aa) |
| | VSTM2A | Zgc:110852. (229 aa) |
| | crkl | V-crk sarcoma virus CT10 oncogene homolog (Avian)-like. (305 aa) |
| | rab35b | RAB35, member RAS oncogene family b. (201 aa) |
| | tgfbr2b | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (556 aa) |
| | smad3b | Mothers against decapentaplegic homolog. (423 aa) |
| | acvrl1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (499 aa) |
| | smad3a | Mothers against decapentaplegic homolog. (425 aa) |
| | hjv | Hemojuvelin BMP co-receptor. (410 aa) |
| | wnt2bb | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (396 aa) |
| | fgf10a | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa) |
| | kdr | Vascular endothelial growth factor receptor 2; Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels. Particularly involved in artery formation. Does not appear to be required for hematopoiesis. (1357 aa) |
| | rab14l | RAB14, member RAS oncogene family,-like. (215 aa) |
| | fgf5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (225 aa) |
| | eef2k | Eukaryotic elongation factor 2 kinase. (706 aa) |
| | map2k5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (450 aa) |
| | tab1 | TGF-beta-activated kinase 1/MAP3K7-binding protein 1. (346 aa) |
| | smad5 | Mothers against decapentaplegic homolog 5; Involved in ventralization. May mediate Bmp2b signaling during early phases of embryonic dorsal-ventral pattern formation. Required for initiation of Smad1 expression during gastrulation. Belongs to the dwarfin/SMAD family. (464 aa) |
| | bmp15 | Bone morphogenetic protein 15. (384 aa) |
| | fgf24 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | stk16 | Serine/threonine kinase 16. (306 aa) |
| | ramp2 | Receptor (G protein-coupled) activity-modifying protein 2. (206 aa) |
| | gdf3 | Protein DVR-1; Serves to facilitate the differentiation of either mesoderm or endoderm either as a cofactor in an instructive signal or by providing permissive environment. (355 aa) |
| | nrp2b | Neuropilin; Belongs to the neuropilin family. (920 aa) |
| | skila | SKI-like proto-oncogene a. (623 aa) |
| | bmpr2a | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1003 aa) |
| | fgf8b | Fibroblast growth factor 8b; May act as signaling molecule during development of the midbrain-hindbrain boundary (MHB) organizer, and be involved in patterning of the nervous system. (212 aa) |
| | cldn1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa) |
| | lrrc32 | Leucine-rich repeat-containing 32. (659 aa) |
| | id1 | Inhibitor of DNA-binding 1, HLH protein. (128 aa) |
| | hspb1 | Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (199 aa) |
| | tgfb1a | Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa) |
| | fgf16 | Fibroblast growth factor 16; Plays a crucial role in pectoral fin bud outgrowth. Belongs to the heparin-binding growth factors family. (203 aa) |
| | tgfbr1b | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa) |
| | fgf1b | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (102 aa) |
| | ccn2a | Novel protein similar to vertebrate connective tissue growth factor (CTGF). (345 aa) |
| | mstna | Growth differentiation factor 8, like. (366 aa) |
| | bag4 | BCL2-associated athanogene 4. (399 aa) |
| | jun | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (308 aa) |
| | zpr1 | ZPR1 zinc finger. (441 aa) |
| | cldn5a | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa) |
| | lft2 | Left-right determination factor. (362 aa) |
| | ngfb | Nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons (By similarity). (194 aa) |
| | itgb6 | Integrin beta; Belongs to the integrin beta chain family. (782 aa) |
| | gdf11 | Growth differentiation factor 11. (390 aa) |
| | fgf23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (258 aa) |
| | fgf6b | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa) |
| | frs2a | Fibroblast growth factor receptor substrate 2a. (485 aa) |
| | dstyk | Dual serine/threonine and tyrosine protein kinase; May act as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death (By similarity). Plays a role in the embryonic development. (857 aa) |
| | dtymk | Deoxythymidylate kinase (thymidylate kinase). (212 aa) |
| | acvr1bb | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (498 aa) |
| | bmp4 | Bone morphogenetic protein 4. (400 aa) |
| | fgfr1b | Fibroblast growth factor receptor. (766 aa) |
| | F1QAH4_DANRE | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (590 aa) |
| | bambia | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (258 aa) |
| | crk | V-crk sarcoma virus CT10 oncogene homolog (Avian). (311 aa) |
| | ube3a | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (857 aa) |
| | F1QQY3_DANRE | Sortilin. (423 aa) |
| | ext2 | Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa) |
| | ndr1 | Nodal-related 1. (392 aa) |
| | itgb5 | Integrin beta; Belongs to the integrin beta chain family. (823 aa) |
| | flt3 | Fms-related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (956 aa) |
| | ntf3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (243 aa) |
| | tgfbr2a | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (645 aa) |
| | fgfrl1a | Fibroblast growth factor receptor-like 1a. (483 aa) |
| | dusp3b | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (177 aa) |
| | dusp3a | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (200 aa) |
| | sost | Sclerostin. (210 aa) |
| | glg1a | Golgi glycoprotein 1a. (1151 aa) |
| | bmp10 | Bone morphogenetic protein 10. (485 aa) |
| | flcn | Folliculin. (558 aa) |
| | baiap2a | BAR/IMD domain-containing adaptor protein 2a. (514 aa) |
| | LOC101882918 | Si:dkeyp-9d4.4. (663 aa) |
| | cep57 | Centrosomal protein 57. (328 aa) |
| | gas1b | Growth arrest-specific 1b. (263 aa) |
| | sirt1 | Sirtuin 1. (710 aa) |
| | LOC100334443 | Sb:cb81. (361 aa) |
| | yap1 | Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Required for expansion of the neural plate and neural plate border zone progenitor pools. Acts as a direct regulator of pax3 expression via interaction with tead1. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin netwo [...] (442 aa) |
| | sostdc1a | Sclerostin domain-containing 1a. (196 aa) |
| | mstnb | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth. May down-regulate muscle-specific transcription factors such as myod and myog. (374 aa) |
| | smad6b | Mothers against decapentaplegic homolog. (486 aa) |
| | vegfc | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (396 aa) |
| | sfrp2 | Secreted frizzled-related protein 2. (294 aa) |
| | bmp8a | Bone morphogenetic protein 8a. (433 aa) |
| | wnt2ba | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (387 aa) |
| | pdgfra | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for pdgfa, pdgfb and pdgfc and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound [...] (1456 aa) |
| | stmn2a | Stathmin; Belongs to the stathmin family. (180 aa) |
| | acvr2aa | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (538 aa) |
| | nrros | Transforming growth factor beta activator LRRC33; Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGFB1, and regulates integrin-dependent activation of TGF-beta-1. TGF- beta-1 activation mediated by lrrc33/nrros is highly localized: there is little spreading of TGF-beta-1 activated from one microglial cell to neighbo [...] (685 aa) |
| | tgfb5 | Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa) |
| | smad4a | Mothers against decapentaplegic homolog. (547 aa) |
| | ankrd1a | Ankyrin repeat domain 1a (cardiac muscle). (317 aa) |
| | clec3ba | C-type lectin domain family 3, member Ba. (197 aa) |
| | il10 | Interleukin-10. (180 aa) |
| | flrt1b | Fibronectin leucine-rich transmembrane protein 1b. (715 aa) |
| | kif16bb | Kinesin family member 16Bb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1309 aa) |
| | gb:cr929477 | SMAD family member 4. (332 aa) |
| | nlk1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (475 aa) |
| | appl2 | Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper-containing 2. (662 aa) |
| | trim71 | E3 ubiquitin-protein ligase TRIM71; E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and participates in post-transcriptional repression of transcripts. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development. (824 aa) |
| | cited1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (152 aa) |
| | fgf22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | magi2b | Membrane-associated guanylate kinase, WW and PDZ domain-containing 2b. (1332 aa) |
| | fgf9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (142 aa) |
| | cdh5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (767 aa) |
| | hspb15 | Heat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (154 aa) |
| | tnfrsf1b | Tumor necrosis factor receptor superfamily, member 1B. (425 aa) |
| | skilb | SKI-like proto-oncogene b. (624 aa) |
| | rab14 | RAB14, member RAS oncogene family. (215 aa) |
| | acvr2ba | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa) |
| | ccbe1 | Collagen and calcium-binding EGF domain-containing protein 1; Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. Necessary for lymphangiogenesis, but is probably not part of either the vegfc-vegfr3 signaling or sox18-prox1 transcriptional pathways. Belongs to the CCBE1 family. (401 aa) |
| | xbp1 | Transcription factor Treb5. (263 aa) |
| | fgf18a | Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (208 aa) |
| | smad2 | Mothers against decapentaplegic homolog 2; Promotes differentiation of dorsal tissues. May be involved in the mediation of Ndr2 signaling during mesoderm and axis formation during embryogenesis. (469 aa) |
| | bmpr2b | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1071 aa) |
| | fut8b | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (579 aa) |
| | fgf20b | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | bmp2b | Bone morphogenetic protein 2b. (411 aa) |
| | nlk2 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (533 aa) |
| | tbx2b | T-box transcription factor TBX2b; Involved in the transcriptional regulation of genes required for mesoderm differentiation. Plays a role in the specification of late notochordal precursor cells and formation of the differentiated notochord. Required for cardiac atrioventricular canal formation. (687 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (491 aa) |
| | slc33a1 | Solute carrier family 33 member 1. (541 aa) |
| | vegfba | Vascular endothelial growth factor Ba; Belongs to the PDGF/VEGF growth factor family. (246 aa) |
| | fez1 | Fasciculation and Elongation protein zeta 1 (Zygin I). (394 aa) |
| | egr3 | Early growth response 3. (422 aa) |
| | tmem108 | Transmembrane protein 108. (524 aa) |
| | prdm14 | PR domain-containing 14. (568 aa) |
| | si:dkey-27o4.1 | Si:dkey-27o4.1. (1642 aa) |
| | rapgef1b | Rap guanine nucleotide exchange factor (GEF) 1b. (1188 aa) |
| | tgfbr1a | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa) |
| | ngfra | Nerve growth factor receptor a (TNFR superfamily, member 16). (346 aa) |
| | smad6a | Mothers against decapentaplegic homolog. (456 aa) |
| | stmn2b | Stathmin; Belongs to the stathmin family. (180 aa) |
| | zyx | Zyxin. (608 aa) |
| | zfyve27 | Zinc finger, FYVE domain-containing 27. (409 aa) |
| | zfp36l2 | Zinc finger protein 36, C3H type-like 2. (373 aa) |
| | spaw | Southpaw. (411 aa) |
| | lef1 | Lymphocyte enhancer binding factor 1 Lef1. (365 aa) |
| | phox2ba | Paired-like homeobox 2Ba. (155 aa) |
| | frs2b | Fibroblast growth factor receptor substrate 2b. (508 aa) |
| | vegfbb | Vascular endothelial growth factor Bb; Belongs to the PDGF/VEGF growth factor family. (91 aa) |
| | rapgef1a | Rap guanine nucleotide exchange factor (GEF) 1a. (1077 aa) |
| | usp9 | Ubiquitin-specific peptidase 9; Belongs to the peptidase C19 family. (2551 aa) |
| | F1QAN5_DANRE | Si:ch73-334d15.2. (128 aa) |
