STRINGSTRING
f2 f2 cldn1 cldn1 rreb1b rreb1b nfe2l2a nfe2l2a ccn4a ccn4a serpine1 serpine1 F2R F2R ano6 ano6 st3gal4 st3gal4 hbegfa hbegfa ccn4b ccn4b mtor mtor nfe2l2b nfe2l2b xbp1 xbp1 F2R-3 F2R-3 vegfba vegfba hbegfb hbegfb F2R-5 F2R-5 vegfbb vegfbb fermt1 fermt1 serpinf2a serpinf2a serpinf2b serpinf2b tbxa2r tbxa2r emilin2b emilin2b rreb1a rreb1a enpp4 enpp4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
f2Coagulation factor II (thrombin); Belongs to the peptidase S1 family. (635 aa)
cldn1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (210 aa)
rreb1bRas-responsive element-binding protein 1b. (1671 aa)
nfe2l2aNuclear factor (Erythroid-derived 2)-like 2. (586 aa)
ccn4aCellular communication network factor 4a. (360 aa)
serpine1Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (392 aa)
F2RSi:dkey-163m14.2. (462 aa)
ano6Anoctamin. (910 aa)
st3gal4ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (335 aa)
hbegfaHeparin-binding EGF-like growth factor a. (230 aa)
ccn4bCellular communication network factor 4b. (356 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2563 aa)
nfe2l2bNuclear factor, erythroid 2-like 2b. (507 aa)
xbp1Transcription factor Treb5. (263 aa)
F2R-3Si:dkey-163m14.4. (438 aa)
vegfbaVascular endothelial growth factor Ba; Belongs to the PDGF/VEGF growth factor family. (246 aa)
hbegfbHeparin-binding EGF-like growth factor b. (263 aa)
F2R-5Si:dkey-163m14.6. (411 aa)
vegfbbVascular endothelial growth factor Bb; Belongs to the PDGF/VEGF growth factor family. (91 aa)
fermt1Fermitin family member 1. (661 aa)
serpinf2aAlpha-2-antiplasmin; Belongs to the serpin family. (457 aa)
serpinf2bAlpha-2-antiplasmin; Belongs to the serpin family. (480 aa)
tbxa2rThromboxane A2 receptor. (202 aa)
emilin2bElastin microfibril interfacer 2b. (805 aa)
rreb1aRas-responsive element-binding protein 1a. (1711 aa)
enpp4Bis(5'-adenosyl)-triphosphatase enpp4; Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors (By similarity); Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. (459 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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