Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A5PN27_DANRE | nsmce2 | ENSDARP00000076074 | ENSDARP00000129789 | Si:dkey-119f1.1. | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | 0.986 |
| A5PN27_DANRE | smc5 | ENSDARP00000076074 | ENSDARP00000091965 | Si:dkey-119f1.1. | Structural maintenance of chromosomes 5. | 0.989 |
| A5PN27_DANRE | smc6 | ENSDARP00000076074 | ENSDARP00000154579 | Si:dkey-119f1.1. | Structural maintenance of chromosomes 6. | 0.566 |
| A5PN27_DANRE | wrn | ENSDARP00000076074 | ENSDARP00000133164 | Si:dkey-119f1.1. | WRN RecQ-like helicase. | 0.767 |
| becn1 | cdkn2a/b | ENSDARP00000100986 | ENSDARP00000145630 | Beclin-1; Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3- phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 P [...] | Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). | 0.409 |
| becn1 | sirt1 | ENSDARP00000100986 | ENSDARP00000088981 | Beclin-1; Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3- phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 P [...] | Sirtuin 1. | 0.726 |
| becn1 | tp53 | ENSDARP00000100986 | ENSDARP00000116736 | Beclin-1; Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3- phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 P [...] | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.787 |
| becn1 | wrn | ENSDARP00000100986 | ENSDARP00000133164 | Beclin-1; Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3- phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 P [...] | WRN RecQ-like helicase. | 0.557 |
| brca2 | cdkn2a/b | ENSDARP00000099674 | ENSDARP00000145630 | BRCA2 DNA repair-associated. | Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). | 0.620 |
| brca2 | smc5 | ENSDARP00000099674 | ENSDARP00000091965 | BRCA2 DNA repair-associated. | Structural maintenance of chromosomes 5. | 0.486 |
| brca2 | tp53 | ENSDARP00000099674 | ENSDARP00000116736 | BRCA2 DNA repair-associated. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.969 |
| brca2 | wrn | ENSDARP00000099674 | ENSDARP00000133164 | BRCA2 DNA repair-associated. | WRN RecQ-like helicase. | 0.925 |
| cdkn2a/b | becn1 | ENSDARP00000145630 | ENSDARP00000100986 | Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). | Beclin-1; Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3- phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis (By similarity). Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 P [...] | 0.409 |
| cdkn2a/b | brca2 | ENSDARP00000145630 | ENSDARP00000099674 | Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). | BRCA2 DNA repair-associated. | 0.620 |
| cdkn2a/b | sirt1 | ENSDARP00000145630 | ENSDARP00000088981 | Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). | Sirtuin 1. | 0.434 |
| cdkn2a/b | tp53 | ENSDARP00000145630 | ENSDARP00000116736 | Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.965 |
| hmga2 | tp53 | ENSDARP00000074985 | ENSDARP00000116736 | High mobility group AT-hook 2. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.558 |
| mapkapk5 | tp53 | ENSDARP00000113922 | ENSDARP00000116736 | Mitogen-activated protein kinase-activated protein kinase 5. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of bax and fas antigen expression, or by repression of Bcl-2 expression. | 0.621 |
| nsmce2 | A5PN27_DANRE | ENSDARP00000129789 | ENSDARP00000076074 | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | Si:dkey-119f1.1. | 0.986 |
| nsmce2 | smc5 | ENSDARP00000129789 | ENSDARP00000091965 | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | Structural maintenance of chromosomes 5. | 0.999 |
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