(17 nodes) Glial cell projection network (Danio rerio)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	I3ITM8_DANRE	Si:ch73-362m14.4. (501 aa)
	sirt2	NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors (By similarity). Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter. Thereby con [...] (379 aa)
	pink1	PTEN-induced kinase 1. (574 aa)
	aqp4	Si:ch211-192k9.1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (320 aa)
	F1QSV1_DANRE	Si:ch73-352p4.8. (492 aa)
	crb2a	Crumbs cell polarity complex component 2a. (1466 aa)
	wasf3b	WASP family member 3b. (481 aa)
	zgc:109889	Zgc:109889 protein. (279 aa)
	fmr1	FMRP translational regulator 1. (569 aa)
	wasf3a	WASP family member 3a. (433 aa)
	crb2b	Crumbs cell polarity complex component 2b. (1010 aa)
	slc1a2b	Amino acid transporter. (564 aa)
	crb1	Crumbs cell polarity complex component 1. (1428 aa)
	LOC101885864	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (277 aa)
	slc1a9	Amino acid transporter. (424 aa)
	slc7a11	Solute carrier family 7 member 11. (498 aa)
	slc1a2a	Amino acid transporter. (548 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
F1QSV1_DANRE	slc7a11	ENSDARP00000059439	ENSDARP00000142449	Si:ch73-352p4.8.	Solute carrier family 7 member 11.	0.902
I3ITM8_DANRE	wasf3a	ENSDARP00000126299	ENSDARP00000113993	Si:ch73-362m14.4.	WASP family member 3a.	0.558
I3ITM8_DANRE	wasf3b	ENSDARP00000126299	ENSDARP00000085962	Si:ch73-362m14.4.	WASP family member 3b.	0.902
I3ITM8_DANRE	zgc:109889	ENSDARP00000126299	ENSDARP00000092197	Si:ch73-362m14.4.	Zgc:109889 protein.	0.901
LOC101885864	slc1a2a	ENSDARP00000139612	ENSDARP00000143007	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Amino acid transporter.	0.458
LOC101885864	slc1a2b	ENSDARP00000139612	ENSDARP00000134622	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Amino acid transporter.	0.431
aqp4	slc1a2a	ENSDARP00000021578	ENSDARP00000143007	Si:ch211-192k9.1; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Amino acid transporter.	0.507
aqp4	slc1a2b	ENSDARP00000021578	ENSDARP00000134622	Si:ch211-192k9.1; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Amino acid transporter.	0.556
pink1	sirt2	ENSDARP00000014981	ENSDARP00000003412	PTEN-induced kinase 1.	NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors (By similarity). Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter. Thereby con [...]	0.586
sirt2	pink1	ENSDARP00000003412	ENSDARP00000014981	NAD-dependent protein deacetylase sirtuin-2; NAD-dependent protein deacetylase, which deacetylates internal lysines on histone and alpha-tubulin as well as many other proteins such as key transcription factors (By similarity). Participates in the modulation of multiple and diverse biological processes such as cell cycle control, genomic integrity, microtubule dynamics, cell differentiation, metabolic networks, and autophagy. Plays a major role in the control of cell cycle progression and genomic stability. Deacetylates histone H4 at 'Lys-16' (H4K16ac) at the VEGFA promoter. Thereby con [...]	PTEN-induced kinase 1.	0.586
slc1a2a	LOC101885864	ENSDARP00000143007	ENSDARP00000139612	Amino acid transporter.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.458
slc1a2a	aqp4	ENSDARP00000143007	ENSDARP00000021578	Amino acid transporter.	Si:ch211-192k9.1; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.507
slc1a2a	slc7a11	ENSDARP00000143007	ENSDARP00000142449	Amino acid transporter.	Solute carrier family 7 member 11.	0.417
slc1a2b	LOC101885864	ENSDARP00000134622	ENSDARP00000139612	Amino acid transporter.	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.431
slc1a2b	aqp4	ENSDARP00000134622	ENSDARP00000021578	Amino acid transporter.	Si:ch211-192k9.1; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.556
slc1a9	slc7a11	ENSDARP00000140209	ENSDARP00000142449	Amino acid transporter.	Solute carrier family 7 member 11.	0.433
slc7a11	F1QSV1_DANRE	ENSDARP00000142449	ENSDARP00000059439	Solute carrier family 7 member 11.	Si:ch73-352p4.8.	0.902
slc7a11	slc1a2a	ENSDARP00000142449	ENSDARP00000143007	Solute carrier family 7 member 11.	Amino acid transporter.	0.417
slc7a11	slc1a9	ENSDARP00000142449	ENSDARP00000140209	Solute carrier family 7 member 11.	Amino acid transporter.	0.433
wasf3a	I3ITM8_DANRE	ENSDARP00000113993	ENSDARP00000126299	WASP family member 3a.	Si:ch73-362m14.4.	0.558

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