STRINGSTRING
bsg bsg opn1sw2 opn1sw2 magi2a magi2a guca1b guca1b guca1a guca1a mkks mkks ift88 ift88 LOC567498 LOC567498 rd3 rd3 prph2a prph2a rrh rrh dync2li1 dync2li1 cetn4 cetn4 gnat2 gnat2 gnat1 gnat1 guca1d guca1d opn1lw2 opn1lw2 opn1lw1 opn1lw1 ift52 ift52 opn1sw1 opn1sw1 rcvrna rcvrna opn3 opn3 E9QHT0_DANRE E9QHT0_DANRE rgra rgra drd7 drd7 rpgra rpgra bbs7 bbs7 crb2a crb2a ush2a ush2a rpgrb rpgrb arl13b arl13b toporsa toporsa rhol rhol pex6 pex6 rom1b rom1b arl3b arl3b cdc14ab cdc14ab drd1a drd1a cerkl cerkl F1R8E9_DANRE F1R8E9_DANRE whrna whrna glis2a glis2a magi2b magi2b zgc:194392 zgc:194392 bbs4 bbs4 dzip1 dzip1 RGS9BP RGS9BP phyh phyh rpgrip1l rpgrip1l kif17 kif17 gucy2f gucy2f nphp4 nphp4 fam161a fam161a fam161b fam161b ift140 ift140 gucy2d gucy2d rp1 rp1 lca5 lca5 elmod3 elmod3 ift80 ift80 nxnl1 nxnl1 shank2b shank2b rpgrip1 rpgrip1 pkd2l1 pkd2l1 whrnb whrnb grxcr1b grxcr1b E9QBF6_DANRE E9QBF6_DANRE pcare2 pcare2 ahi1 ahi1 rp1l1b rp1l1b rp1l1a rp1l1a impg1b impg1b si:dkey-44k1.5 si:dkey-44k1.5 im:7145024 im:7145024 mchr1a mchr1a toporsb toporsb pcare1 pcare1 qrfprb qrfprb kncn kncn glis2b glis2b crb2b crb2b ENSDARP00000132536 ENSDARP00000132536 iqcb1-2 iqcb1-2 iqcb1 iqcb1 pde6gb pde6gb pde6ga pde6ga crb1 crb1 guca1e guca1e cetn2 cetn2 Exorh Exorh ttc8 ttc8 cngb3.1 cngb3.1 lyar lyar cfap410 cfap410 shank2a shank2a gc2 gc2 opn1mw4 opn1mw4 opn1mw1 opn1mw1 opn1mw3 opn1mw3 prph2lb prph2lb rgs9bp rgs9bp kifap3b kifap3b kifap3a kifap3a cdc14aa cdc14aa prph2b prph2b rcvrn2 rcvrn2 rho rho opn1mw2 opn1mw2 smo smo cetn3 cetn3 tbcc tbcc rsph9 rsph9 opn6a opn6a cngb1a cngb1a spata7 spata7 exorh exorh ttll4 ttll4 LOC562466 LOC562466 arl3a arl3a strc1 strc1 mchr1b mchr1b wdr19 wdr19 prph2la prph2la ENSDARP00000145860 ENSDARP00000145860 rcvrnb rcvrnb grxcr1a grxcr1a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bsgBasigin. (404 aa)
opn1sw2Opsin-1, short-wave-sensitive 2; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (354 aa)
magi2aMembrane-associated guanylate kinase, WW and PDZ domain-containing 2a. (1503 aa)
guca1bGuanylate cyclase-activating protein 2. (197 aa)
guca1aGuanylate cyclase activator 1A. (189 aa)
mkksMcKusick-Kaufman syndrome. (563 aa)
ift88Intraflagellar transport 88 homolog. (824 aa)
LOC567498G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (403 aa)
rd3Retinal degeneration 3, GUCY2D regulator. (215 aa)
prph2aPeripherin 2a (retinal degeneration, slow). (345 aa)
rrhRetinal pigment epithelium-derived rhodopsin homolog; Belongs to the G-protein coupled receptor 1 family. (379 aa)
dync2li1Cytoplasmic dynein 2 light intermediate chain 1; Required for correct intraflagellar transport (IFT), the bi- directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Involved in the regulation of ciliary length. (358 aa)
cetn4Centrin 4. (171 aa)
gnat2Guanine nucleotide-binding protein (G protein), alpha transducing activity polypeptide 2. (354 aa)
gnat1Guanine nucleotide-binding protein (G protein), alpha transducing activity polypeptide 1. (350 aa)
guca1dGuanylate cyclase activating protein 4. (185 aa)
opn1lw2Red-sensitive opsin-2; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (356 aa)
opn1lw1Red-sensitive opsin-1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (357 aa)
ift52Intraflagellar transport 52 homolog (Chlamydomonas). (435 aa)
opn1sw1Opsin-1, short-wave-sensitive 1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (336 aa)
rcvrnaRecoverin-1a. (203 aa)
opn3Teleost encephalopsin/panopsin. (387 aa)
E9QHT0_DANRESi:dkey-27p18.2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
rgraRetinal pigment epithelium retinal G protein receptor-1. (295 aa)
drd7Dopamine receptor D7; Belongs to the G-protein coupled receptor 1 family. (443 aa)
rpgraRetinitis pigmentosa GTPase regulator a. (1698 aa)
bbs7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
crb2aCrumbs cell polarity complex component 2a. (1466 aa)
ush2aUsher syndrome 2A (autosomal recessive, mild). (5236 aa)
rpgrbRetinitis pigmentosa GTPase regulator b. (1413 aa)
arl13bADP-ribosylation factor-like protein 13B; Cilium-specific protein required to control the microtubule- based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. Regulates the migration and placement of postmitotic intern [...] (407 aa)
toporsaTopoisomerase I-binding, arginine/serine-rich a. (999 aa)
rholRhodopsin. (355 aa)
pex6Peroxisomal biogenesis factor 6. (1071 aa)
rom1bRetinal outer segment membrane protein 1b. (352 aa)
arl3bADP-ribosylation factor-like protein 3; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase- activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Required for targeting proteins to the ciliary membrane by releasing myristoylated protein from unc119 cargo adapters into the cilium (By similarity). (182 aa)
cdc14abDual specificity protein phosphatase CDC14AB; Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. (510 aa)
drd1aDopamine receptor D1a; Belongs to the G-protein coupled receptor 1 family. (363 aa)
cerklCeramide kinase-like. (577 aa)
F1R8E9_DANRESi:ch211-106h4.9. (1173 aa)
whrnaWhirlin a. (939 aa)
glis2aGLIS family zinc finger 2a. (446 aa)
magi2bMembrane-associated guanylate kinase, WW and PDZ domain-containing 2b. (1332 aa)
zgc:194392Zgc:194392. (142 aa)
bbs4Bardet-Biedl syndrome 4. (528 aa)
dzip1Zinc finger protein Dzip1; Acts as a permissive factor that is required for the proper regulation of Hedgehog (Hh) target genes in response to Hh signals. Acts downstream of the Smoothened protein to modulate Gli activity in the somites of the developing embryo. Required for establishment of left-right asymmetry during embryogenesis. Has a role in primary cilium formation. (897 aa)
RGS9BPSi:ch73-167i17.6. (232 aa)
phyhPhytanoyl-CoA 2-hydroxylase. (335 aa)
rpgrip1lRPGRIP1-like. (1256 aa)
kif17Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (823 aa)
gucy2fGuanylate cyclase. (1107 aa)
nphp4Si:dkey-202c5.1 protein. (189 aa)
fam161aFAM161 centrosomal protein A. (803 aa)
fam161bFAM161 centrosomal protein B. (574 aa)
ift140Intraflagellar transport 140 homolog (Chlamydomonas). (1445 aa)
gucy2dGuanylate cyclase. (1176 aa)
rp1RP1 axonemal microtubule-associated. (259 aa)
lca5Lebercilin LCA5. (754 aa)
elmod3ELMO/CED-12 domain-containing 3. (327 aa)
ift80Intraflagellar transport 80 homolog (Chlamydomonas). (777 aa)
nxnl1Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods. Belongs to the nucleoredoxin family. (215 aa)
shank2bSH3 and multiple ankyrin repeat domains 2b. (1800 aa)
rpgrip1RPGR-interacting protein 1. (1342 aa)
pkd2l1Polycystic kidney disease 2-like 1. (790 aa)
whrnbWhirlin b. (946 aa)
grxcr1bGlutaredoxin and cysteine-rich domain-containing 1 b. (148 aa)
E9QBF6_DANRESi:dkey-126g1.9. (135 aa)
pcare2Photoreceptor cilium actin regulator 2. (859 aa)
ahi1Abelson helper integration site 1. (1193 aa)
rp1l1bRp1-like 1b. (3919 aa)
rp1l1aRp1-like 1a. (2394 aa)
impg1bInterphotoreceptor matrix proteoglycan 1b. (936 aa)
si:dkey-44k1.5Si:dkey-44k1.5. (1354 aa)
im:7145024Im:7145024. (229 aa)
mchr1aMelanin-concentrating hormone receptor 1a. (322 aa)
toporsbTopoisomerase I-binding, arginine/serine-rich b. (939 aa)
pcare1Uncharacterized protein. (1122 aa)
qrfprbG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (428 aa)
kncnKinocilin. (118 aa)
glis2bGLIS family zinc finger 2b. (489 aa)
crb2bCrumbs cell polarity complex component 2b. (1010 aa)
ENSDARP00000132536Si:ch211-103a14.5. (199 aa)
iqcb1-2IQ motif-containing B1. (421 aa)
iqcb1IQ motif-containing B1. (595 aa)
pde6gbPhosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b. (87 aa)
pde6gaPhosphodiesterase 6G, cGMP-specific, rod, gamma, paralog a. (86 aa)
crb1Crumbs cell polarity complex component 1. (1428 aa)
guca1eGuanylate cyclase activator 1e. (198 aa)
cetn2Centrin, EF-hand protein, 2. (172 aa)
ExorhRhodopsin. (168 aa)
ttc8Tetratricopeptide repeat domain 8. (268 aa)
cngb3.1Cyclic nucleotide-gated channel subunit beta 3, tandem duplicate 1. (786 aa)
lyarLy1 antibody reactive homolog (mouse). (243 aa)
cfap410Cilia and flagella-associated protein 410. (364 aa)
shank2aSH3 and multiple ankyrin repeat domains 2a. (1306 aa)
gc2Guanylate cyclase. (1107 aa)
opn1mw4Green-sensitive opsin-4; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (349 aa)
opn1mw1Green-sensitive opsin-1; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. (349 aa)
opn1mw3Green-sensitive opsin-3; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (349 aa)
prph2lbSi:dkey-85n7.2 protein. (359 aa)
rgs9bpRegulator of G-protein-signaling 9-binding protein. (254 aa)
kifap3bKinesin-associated protein 3b. (772 aa)
kifap3aKinesin-associated protein 3a. (789 aa)
cdc14aaCell division cycle 14Aa. (592 aa)
prph2bPeripherin 2b (retinal degeneration, slow). (342 aa)
rcvrn2Recoverin-2a. (193 aa)
rhoRhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity). (354 aa)
opn1mw2Green-sensitive opsin-2; Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (349 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (822 aa)
cetn3Centrin 3. (167 aa)
tbccTubulin folding cofactor C. (350 aa)
rsph9Radial spoke head protein 9 homolog; Probable component of the axonemal radial spoke head (By similarity). Radial spokes are regularly spaced along cilia, sperm and flagella axonemes. They consist of a thin stalk, which is attached to a subfiber of the outer doublet microtubule, and a bulbous head, which is attached to the stalk and appears to interact with the projections from the central pair of microtubules. (277 aa)
opn6aOpsin 6, group member a. (419 aa)
cngb1aCyclic nucleotide-gated channel subunit beta 1a. (822 aa)
spata7Spermatogenesis-associated 7. (500 aa)
exorhExtra-ocular rhodopsin. (122 aa)
ttll4Tubulin tyrosine ligase-like family, member 4. (1070 aa)
LOC562466Cyclic nucleotide-gated channel subunit beta 3, tandem duplicate 2. (715 aa)
arl3aADP ribosylation factor-like GTPase 3a; Belongs to the small GTPase superfamily. Arf family. (182 aa)
strc1Stereocilin 1. (2032 aa)
mchr1bMelanin-concentrating hormone receptor 1b. (364 aa)
wdr19WD repeat domain 19. (1372 aa)
prph2laPeripherin 2-like a. (364 aa)
ENSDARP00000145860Uncharacterized protein. (83 aa)
rcvrnbRecoverin-1b. (203 aa)
grxcr1aGlutaredoxin and cysteine-rich domain-containing 1 a. (295 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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