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aurkb aurkb nf1b nf1b ccl19b ccl19b ripk3 ripk3 mertka mertka lgals3a lgals3a LOC100002406 LOC100002406 il10 il10 ccl19a.1 ccl19a.1 sirt1 sirt1 noc2l noc2l prelid1b prelid1b lgals3b lgals3b p2rx7 p2rx7 F1QSV1_DANRE F1QSV1_DANRE il7r il7r efna1a efna1a gas6 gas6 efna1b efna1b kifap3a kifap3a rapgef6 rapgef6 rapgef2 rapgef2 AXL AXL slc7a11 slc7a11 prelid1a prelid1a fnip1 fnip1 fadd fadd kifap3b kifap3b nf1a nf1a gpam gpam
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aurkbAurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] (320 aa)
nf1bNeurofibromin 1b. (2759 aa)
ccl19bChemokine (C-C motif) ligand 19b. (128 aa)
ripk3Receptor-interacting serine-threonine kinase 3. (361 aa)
mertkaC-mer proto-oncogene tyrosine kinase a. (952 aa)
lgals3aGalectin. (332 aa)
LOC100002406Solute carrier family 46 member 2. (406 aa)
il10Interleukin-10. (180 aa)
ccl19a.1C-C motif chemokine. (119 aa)
sirt1Sirtuin 1. (710 aa)
noc2lNOC2-like nucleolar-associated transcriptional repressor. (752 aa)
prelid1bPRELI domain-containing 1b. (199 aa)
lgals3bGalectin. (252 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa)
F1QSV1_DANRESi:ch73-352p4.8. (492 aa)
il7rInterleukin 7 receptor. (372 aa)
efna1aEphrin-A1a; Belongs to the ephrin family. (222 aa)
gas6Growth arrest-specific 6. (648 aa)
efna1bEphrin A-L1; Belongs to the ephrin family. (229 aa)
kifap3aKinesin-associated protein 3a. (789 aa)
rapgef6Rap guanine nucleotide exchange factor (GEF) 6. (1261 aa)
rapgef2Rap guanine nucleotide exchange factor (GEF) 2. (1619 aa)
AXLAXL receptor tyrosine kinase. (786 aa)
slc7a11Solute carrier family 7 member 11. (498 aa)
prelid1aPRELI domain-containing 1a. (210 aa)
fnip1Folliculin-interacting protein 1. (1077 aa)
faddFas (tnfrsf6)-associated via death domain. (192 aa)
kifap3bKinesin-associated protein 3b. (772 aa)
nf1aNeurofibromin 1a. (2759 aa)
gpamGlycerol-3-phosphate acyltransferase 1, mitochondrial. (826 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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