(25 nodes) Regulation of transcription regulatory region DNA binding network (Danio rerio)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gtf2b	General transcription factor IIB. (316 aa)
	ep300a	E1A-binding protein p300 a. (2679 aa)
	msx1a	Muscle segment homeobox 1a. (233 aa)
	rnf220b	Ring finger protein 220b. (362 aa)
	ENSDARP00000151202	Peptidase_M48_N domain-containing protein. (272 aa)
	gata1a	GATA-binding protein 1a. (418 aa)
	igf2a	Insulin-like growth factor 2a. (197 aa)
	ankrd33ab	Ankyrin repeat domain 33Ab. (462 aa)
	rb1	Retinoblastoma 1. (903 aa)
	GCA	Zgc:92027. (205 aa)
	tgfb1a	Transforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
	ankrd33ba	Ankyrin repeat domain 33ba. (510 aa)
	sri	Sorcin. (190 aa)
	gata1b	GATA-binding protein 1b. (361 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (468 aa)
	ddit3	DNA-damage-inducible transcript 3. (242 aa)
	nsd1a	Nuclear receptor-binding SET domain protein 1a. (2071 aa)
	rnf220a	Ring finger protein 220a. (307 aa)
	dot1l	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1454 aa)
	nsd1b	Nuclear receptor-binding SET domain protein 1b. (1873 aa)
	ankrd33aa	Ankyrin repeat domain 33Aa. (428 aa)
	znf593	Zinc finger protein 593. (129 aa)
	tgfb1b	Transforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
	ankrd33bb	Ankyrin repeat domain 33Bb. (448 aa)
	ep300b	E1A-binding protein p300 b. (2615 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ep300a	gata1a	ENSDARP00000140048	ENSDARP00000002330	E1A-binding protein p300 a.	GATA-binding protein 1a.	0.429
ep300a	gata1b	ENSDARP00000140048	ENSDARP00000076594	E1A-binding protein p300 a.	GATA-binding protein 1b.	0.429
ep300a	gtf2b	ENSDARP00000140048	ENSDARP00000137822	E1A-binding protein p300 a.	General transcription factor IIB.	0.640
ep300a	rb1	ENSDARP00000140048	ENSDARP00000021737	E1A-binding protein p300 a.	Retinoblastoma 1.	0.417
ep300b	gata1a	ENSDARP00000129212	ENSDARP00000002330	E1A-binding protein p300 b.	GATA-binding protein 1a.	0.702
ep300b	gata1b	ENSDARP00000129212	ENSDARP00000076594	E1A-binding protein p300 b.	GATA-binding protein 1b.	0.432
ep300b	gtf2b	ENSDARP00000129212	ENSDARP00000137822	E1A-binding protein p300 b.	General transcription factor IIB.	0.640
ep300b	rb1	ENSDARP00000129212	ENSDARP00000021737	E1A-binding protein p300 b.	Retinoblastoma 1.	0.417
ep300b	tgfb1a	ENSDARP00000129212	ENSDARP00000060838	E1A-binding protein p300 b.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.508
gata1a	ep300a	ENSDARP00000002330	ENSDARP00000140048	GATA-binding protein 1a.	E1A-binding protein p300 a.	0.429
gata1a	ep300b	ENSDARP00000002330	ENSDARP00000129212	GATA-binding protein 1a.	E1A-binding protein p300 b.	0.702
gata1b	ep300a	ENSDARP00000076594	ENSDARP00000140048	GATA-binding protein 1b.	E1A-binding protein p300 a.	0.429
gata1b	ep300b	ENSDARP00000076594	ENSDARP00000129212	GATA-binding protein 1b.	E1A-binding protein p300 b.	0.432
gtf2b	ep300a	ENSDARP00000137822	ENSDARP00000140048	General transcription factor IIB.	E1A-binding protein p300 a.	0.640
gtf2b	ep300b	ENSDARP00000137822	ENSDARP00000129212	General transcription factor IIB.	E1A-binding protein p300 b.	0.640
igf2a	tgfb1a	ENSDARP00000016954	ENSDARP00000060838	Insulin-like growth factor 2a.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.500
igf2a	tgfb1b	ENSDARP00000016954	ENSDARP00000122056	Insulin-like growth factor 2a.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.497
nsd1a	nsd1b	ENSDARP00000156812	ENSDARP00000106822	Nuclear receptor-binding SET domain protein 1a.	Nuclear receptor-binding SET domain protein 1b.	0.484
nsd1b	nsd1a	ENSDARP00000106822	ENSDARP00000156812	Nuclear receptor-binding SET domain protein 1b.	Nuclear receptor-binding SET domain protein 1a.	0.484
rb1	ep300a	ENSDARP00000021737	ENSDARP00000140048	Retinoblastoma 1.	E1A-binding protein p300 a.	0.417

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