STRINGSTRING
phc1 phc1 cbx2 cbx2 cbx8a cbx8a phc3 phc3 cbx8b cbx8b rnf2 rnf2 cbx7b cbx7b cbx6a cbx6a pcgf6 pcgf6 mgst3b mgst3b phc2a phc2a cbx7a cbx7a cbx4 cbx4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
phc1Polyhomeotic homolog 1. (901 aa)
cbx2Chromobox homolog 2 (Drosophila Pc class). (514 aa)
cbx8aChromobox homolog 8a (Pc class homolog, Drosophila). (342 aa)
phc3Polyhomeotic homolog 3 (Drosophila). (173 aa)
cbx8bChromobox homolog 8b. (361 aa)
rnf2E3 ubiquitin-protein ligase RING2; E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin he [...] (338 aa)
cbx7bChromobox homolog 7b. (239 aa)
cbx6aChromobox homolog 6a. (411 aa)
pcgf6Polycomb group ring finger 6. (277 aa)
mgst3bMicrosomal glutathione S-transferase 3b. (140 aa)
phc2aPolyhomeotic-like protein 2; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity). (310 aa)
cbx7aChromobox homolog 7a. (395 aa)
cbx4Chromobox homolog 4 (Pc class homolog, Drosophila). (477 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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