STRINGSTRING
eomesa eomesa tbx6 tbx6 tbr1b tbr1b tbx21 tbx21 tbx4 tbx4 tbx16l tbx16l tbx3b tbx3b tbx2b tbx2b tbx1 tbx1 tbr1a tbr1a tbx5a tbx5a tbx22 tbx22 eomesb eomesb tbxta tbxta tbx2a tbx2a tbx20 tbx20 tbx3a tbx3a mgaa mgaa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
eomesaT-box transcription factor eomesodermin. (661 aa)
tbx6T-box transcription factor TBX6; T-box transcription factor involved in the development of paraxial mesoderm. (874 aa)
tbr1bT-box brain transcription factor 1b. (676 aa)
tbx21T-box transcription factor 21. (609 aa)
tbx4T-box transcription factor 4. (543 aa)
tbx16lT-box transcription factor TBX6L; Probable transcriptional regulator involved in developmental processes. (488 aa)
tbx3bT-box transcription factor 3b. (594 aa)
tbx2bT-box transcription factor TBX2b; Involved in the transcriptional regulation of genes required for mesoderm differentiation. Plays a role in the specification of late notochordal precursor cells and formation of the differentiated notochord. Required for cardiac atrioventricular canal formation. (687 aa)
tbx1T-box transcription factor TBX1; May act as a transcriptional factor. Acts cell autonomously in the pharyngeal mesendoderm and influences the development of neural crest-derived cartilages secondarily. (460 aa)
tbr1aT-box brain transcription factor 1a. (585 aa)
tbx5aT-box transcription factor TBX5-A; Required for pectoral fin formation. Together with tbx5b, involved in eye and heart development. Required for the looping stage of heart development. May bind to the core DNA motif of promoters. (492 aa)
tbx22T-box transcription factor 22. (334 aa)
eomesbEomesodermin homolog b. (534 aa)
tbxtaT-box transcription factor T-A; Involved in the transcriptional regulation of genes required for mesoderm differentiation, including itself. Indispensable for the formation of the notochord and the tail structure. Functions together with tbx16/spadetail in development of trunk and tail mesoderm. Functions by itself early in development to repress medial floor plate and promote notochord fate but at later times, functions together with tbx16/spadetail to promote medial floor plate formation. Acts in a parallel pathway to, but cooperates with, non-canonical wnt-signaling during tail form [...] (423 aa)
tbx2aT-box transcription factor 2a. (686 aa)
tbx20T-box transcription factor TBX20; Transcriptional regulator that may play a very early role in the differentiation of the cardiac precursors. (446 aa)
tbx3aT-box transcription factor 3a. (689 aa)
mgaaMAX dimerization protein MGA a. (2838 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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