STRINGSTRING
hey2 hey2 her8a her8a her4.3 her4.3 her4.5 her4.5 hey1 hey1 her4.1 her4.1 her4.4 her4.4 her9 her9 helt helt heyl heyl bhlhe41 bhlhe41 her2 her2 her12 her12 her4.2 her4.2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hey2Hairy/enhancer-of-split related with YRPW motif protein 2; Transcriptional repressor (By similarity). Downstream effector of Notch signaling which regulates cell fate choice in angioblasts. Represses the venous cell fate, thereby promoting the arterial cell fate and aorta formation; Belongs to the HEY family. (324 aa)
her8aHairy-related 8a. (221 aa)
her4.3Hairy-related 4, tandem duplicate 3. (152 aa)
her4.5Hairy-related 4, tandem duplicate 2. (152 aa)
hey1Hairy/enhancer-of-split related with YRPW motif protein 1; Transcriptional repressor which functions as a downstream effector of Notch signaling; Belongs to the HEY family. (317 aa)
her4.1Hairy-related 4, tandem duplicate 1. (152 aa)
her4.4Hairy-related 4, tandem duplicate 4. (152 aa)
her9BHLH-WRPW transcription factor. (291 aa)
heltHairy and enhancer of split-related protein helt; Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3'; Belongs to the HEY family. (270 aa)
heylHairy/enhancer-of-split related with YRPW motif-like protein; Transcriptional repressor which functions as a downstream effector of Notch signaling. (310 aa)
bhlhe41Novel protein similar to vertebrate basic helix-loop-helix domain containing, class B, 3 (BHLHB3). (421 aa)
her2Hairy-related 2. (108 aa)
her12BHLH transcription factor. (155 aa)
her4.2Hairy-related 4, tandem duplicate 2. (152 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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