STRINGSTRING
hist1h2a5 hist1h2a5 zgc:171759 zgc:171759 taf4a taf4a ano9a ano9a zgc:173587 zgc:173587 E7FFQ2_DANRE E7FFQ2_DANRE taf6l taf6l taf9 taf9 cenps cenps hist1h2a3 hist1h2a3 h2ax1 h2ax1 hist1h2a10 hist1h2a10 hist2h3ca1 hist2h3ca1 ENSDARP00000142232 ENSDARP00000142232 ENSDARP00000142451 ENSDARP00000142451 cenpa cenpa h2az2b h2az2b hist1h2a6 hist1h2a6 pole3 pole3 supt7l supt7l pole4 pole4 taf8 taf8 h2ax h2ax hist2h2l hist2h2l nfyba nfyba drap1 drap1 taf3 taf3 hist1h2a1 hist1h2a1 hist1h2a4 hist1h2a4 zgc:173552 zgc:173552 zgc:194989 zgc:194989 abtb2a abtb2a sos2 sos2 h2az2a h2az2a h3f3a-2 h3f3a-2 btbd11a btbd11a zgc:113983 zgc:113983 abtb2b abtb2b macroh2a1 macroh2a1 supt3h supt3h LOC100535468 LOC100535468 cenpw cenpw h2af1al h2af1al nfyc nfyc btbd11b btbd11b dr1 dr1 taf6 taf6 taf12 taf12 X1WHF1_DANRE X1WHF1_DANRE X1WDH8_DANRE X1WDH8_DANRE R4GE15_DANRE R4GE15_DANRE taf11 taf11 cenpt cenpt cenpx cenpx hist1h2a11-2 hist1h2a11-2 zgc:171759-2 zgc:171759-2 macroh2a2 macroh2a2 LOC100148591 LOC100148591
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hist1h2a5Histone H2A; Belongs to the histone H2A family. (128 aa)
zgc:171759Histone H2B; Belongs to the histone H2B family. (124 aa)
taf4aTAF4A RNA polymerase II, TATA box-binding protein (TBP)-associated factor. (821 aa)
ano9aHistone H2B; Belongs to the histone H2B family. (124 aa)
zgc:173587Histone H2B 1/2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (124 aa)
E7FFQ2_DANRESi:dkey-219c3.2. (976 aa)
taf6lTAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor. (641 aa)
taf9TAF9 RNA polymerase II, TATA box-binding protein (TBP)-associated factor. (248 aa)
cenpsSimilar to apoptosis-inducing, TAF9-like domain 1. (127 aa)
hist1h2a3Histone H2A; Belongs to the histone H2A family. (128 aa)
h2ax1Histone H2A; Belongs to the histone H2A family. (128 aa)
hist1h2a10Histone H2A; Belongs to the histone H2A family. (128 aa)
hist2h3ca1Histone H3; Belongs to the histone H3 family. (136 aa)
ENSDARP00000142232Histone H2B; Belongs to the histone H2B family. (124 aa)
ENSDARP00000142451Histone H2A; Belongs to the histone H2A family. (127 aa)
cenpaHistone H3-like centromeric protein A; Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. Required [...] (145 aa)
h2az2bHistone H2A; Belongs to the histone H2A family. (128 aa)
hist1h2a6Histone H2A; Belongs to the histone H2A family. (127 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (148 aa)
supt7lSuppressor of Ty 7 (S. cerevisiae)-like. (414 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (179 aa)
taf8Transcription initiation factor TFIID subunit 8; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent transcription (By similarity); Belongs to the TAF8 family. (308 aa)
h2axHistone H2AX; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low dos [...] (142 aa)
hist2h2lHistone H2B 3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa)
nfybaNuclear transcription factor Y, beta a. (204 aa)
drap1DR1-associated protein 1 (negative cofactor 2 alpha). (211 aa)
taf3TAF3 RNA polymerase II, TATA box-binding protein (TBP)-associated facto. (898 aa)
hist1h2a1Histone H2A; Belongs to the histone H2A family. (128 aa)
hist1h2a4Histone H2A; Belongs to the histone H2A family. (128 aa)
zgc:173552Histone H3; Belongs to the histone H3 family. (136 aa)
zgc:194989Histone H2B; Belongs to the histone H2B family. (124 aa)
abtb2aAnkyrin repeat and BTB (POZ) domain-containing 2a. (1006 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1341 aa)
h2az2aHistone H2A.V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...] (128 aa)
h3f3a-2Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
btbd11aAnkyrin repeat and BTB/POZ domain-containing protein BTBD11-A. (1021 aa)
zgc:113983Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
abtb2bAnkyrin repeat and BTB (POZ) domain-containing 2b. (1032 aa)
macroh2a1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (357 aa)
supt3hSPT3 homolog, SAGA and STAGA complex component. (380 aa)
LOC100535468CBFD_NFYB_HMF domain-containing protein. (157 aa)
cenpwCentromere protein W. (98 aa)
h2af1alHistone H2A; Belongs to the histone H2A family. (140 aa)
nfycNuclear transcription factor Y, gamma. (360 aa)
btbd11bAnkyrin repeat and BTB/POZ domain-containing protein BTBD11-B. (1042 aa)
dr1Down-regulator of transcription 1. (176 aa)
taf6TAF6 RNA polymerase II, TATA box-binding protein (TBP)-associated factor. (636 aa)
taf12TAF12 RNA polymerase II, TATA box-binding protein (TBP)-associated factor. (162 aa)
X1WHF1_DANREHistone H2B; Belongs to the histone H2B family. (124 aa)
X1WDH8_DANREHistone H2B; Belongs to the histone H2B family. (124 aa)
R4GE15_DANREHistone H2B; Belongs to the histone H2B family. (124 aa)
taf11TAF11 RNA polymerase II, TATA box-binding protein (TBP)-associated factor. (206 aa)
cenptSi:ch211-225g23.1. (914 aa)
cenpxCentromere protein X. (81 aa)
hist1h2a11-2Histone H2A; Belongs to the histone H2A family. (127 aa)
zgc:171759-2Histone H2B; Belongs to the histone H2B family. (124 aa)
macroh2a2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (367 aa)
LOC100148591Histone H2A; Belongs to the histone H2A family. (128 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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