STRINGSTRING
sema3fb sema3fb sema3fa sema3fa sema3h sema3h E7F6D0_DANRE E7F6D0_DANRE M9MMA2_DANRE M9MMA2_DANRE ptgfrn ptgfrn adgra2 adgra2 F1QAI9_DANRE F1QAI9_DANRE igsf5a igsf5a sema3gb sema3gb E7F867_DANRE E7F867_DANRE crtam crtam zgc:172106 zgc:172106 X1WBK1_DANRE X1WBK1_DANRE cd79b cd79b LOC101886098 LOC101886098 nectin4b nectin4b flt4 flt4 kdrl kdrl zgc:113293 zgc:113293 ntrk3b ntrk3b fgfr4 fgfr4 LOC799279 LOC799279 vcam1b vcam1b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sema3fbSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb; Belongs to the semaphorin family. (791 aa)
sema3faSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fa; Belongs to the semaphorin family. (801 aa)
sema3hSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3H; Belongs to the semaphorin family. (749 aa)
E7F6D0_DANRESi:ch73-22o12.1. (505 aa)
M9MMA2_DANRESi:ch211-129c21.1; Belongs to the semaphorin family. (775 aa)
ptgfrnUncharacterized protein. (743 aa)
adgra2Adhesion G protein-coupled receptor A2; Endothelial receptor which functions together with reck to enable brain endothelial cells to selectively respond to Wnt7 signals (wnt7a or wnt7b). Plays a key role in Wnt7-specific responses: Required for normal central nervous system (CNS) vascularization where it functions cell-autonomously in the tip cells of sprouting vessels. Has a role in development of dorsal root ganglia. Acts as a Wnt7-specific coactivator of canonical Wnt signaling: required to deliver reck-bound Wnt7 to frizzled by assembling a higher-order RECK-ADGRA2-Fzd-LRP5-LRP6 co [...] (1367 aa)
F1QAI9_DANRESi:ch211-132g1.7. (864 aa)
igsf5aImmunoglobulin superfamily, member 5a. (322 aa)
sema3gbSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb; Belongs to the semaphorin family. (745 aa)
E7F867_DANRESi:ch211-180a12.2. (903 aa)
crtamIg-like domain-containing protein. (436 aa)
zgc:172106Zgc:172106. (396 aa)
X1WBK1_DANRESi:ch73-380l3.4. (517 aa)
cd79bCD79b molecule, immunoglobulin-associated beta. (263 aa)
LOC101886098Uncharacterized protein. (483 aa)
nectin4bNectin cell adhesion molecule 4b. (570 aa)
flt4Vascular endothelial growth factor receptor 3; Tyrosine-protein kinase that acts as a cell-surface receptor for vegf or vegfc. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels, but not required for proper vasculogenesis or hematopoiesis. (1368 aa)
kdrlVascular endothelial growth factor receptor kdr-like; Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. Combinations of multiple VEGF receptors are required for development of different blood vessel types in the embryo. Involved in angiogenesis, specifically in VEGF-induced sprouting of new blood vessels. Particularly involved in artery formation. Does not appear to be required for hematopoiesis. (1301 aa)
zgc:113293Zgc:113293. (271 aa)
ntrk3bTyrosine-protein kinase receptor. (813 aa)
fgfr4Fibroblast growth factor receptor 4; Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down- regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation o [...] (923 aa)
LOC799279Uncharacterized protein. (547 aa)
vcam1bVascular cell adhesion molecule 1b. (808 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (14%) [HD]