(12 nodes) MHC class II, alpha/beta chain, N-terminal network (Danio rerio)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mhc2a	Major histocompatibility complex class II integral membrane alpha chain gene. (236 aa)
	zgc:103700	Zgc:103700. (250 aa)
	ENSDARP00000151819	Ig-like domain-containing protein. (257 aa)
	ENSDARP00000143185	Si:ch73-158p21.3. (249 aa)
	ENSDARP00000140023	Si:zfos-2070c2.3. (253 aa)
	ENSDARP00000137499	Si:dkey-33b17.3. (277 aa)
	dZ48C11.3-001	Novel protein similar to MHC class II alpha chain. (236 aa)
	mhc2dab	Novel protein similar to vertebrate major histocompatibility complex class II DAB gene (Mhc2dab). (250 aa)
	F1QNN0_DANRE	Si:zfos-367g9.1. (236 aa)
	F1R0K2_DANRE	Si:zfos-2070c2.1. (235 aa)
	mhc2bl	MHC class II beta chain-like. (250 aa)
	M9MM93_DANRE	Si:ch73-211l2.3. (234 aa)

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSDARP00000137499	ENSDARP00000140023	ENSDARP00000137499	ENSDARP00000140023	Si:dkey-33b17.3.	Si:zfos-2070c2.3.	0.550
ENSDARP00000137499	ENSDARP00000143185	ENSDARP00000137499	ENSDARP00000143185	Si:dkey-33b17.3.	Si:ch73-158p21.3.	0.560
ENSDARP00000137499	ENSDARP00000151819	ENSDARP00000137499	ENSDARP00000151819	Si:dkey-33b17.3.	Ig-like domain-containing protein.	0.678
ENSDARP00000137499	F1QNN0_DANRE	ENSDARP00000137499	ENSDARP00000100115	Si:dkey-33b17.3.	Si:zfos-367g9.1.	0.777
ENSDARP00000137499	F1R0K2_DANRE	ENSDARP00000137499	ENSDARP00000093621	Si:dkey-33b17.3.	Si:zfos-2070c2.1.	0.681
ENSDARP00000137499	M9MM93_DANRE	ENSDARP00000137499	ENSDARP00000010619	Si:dkey-33b17.3.	Si:ch73-211l2.3.	0.790
ENSDARP00000137499	dZ48C11.3-001	ENSDARP00000137499	ENSDARP00000136215	Si:dkey-33b17.3.	Novel protein similar to MHC class II alpha chain.	0.675
ENSDARP00000137499	mhc2a	ENSDARP00000137499	ENSDARP00000048447	Si:dkey-33b17.3.	Major histocompatibility complex class II integral membrane alpha chain gene.	0.679
ENSDARP00000137499	mhc2bl	ENSDARP00000137499	ENSDARP00000088705	Si:dkey-33b17.3.	MHC class II beta chain-like.	0.550
ENSDARP00000137499	mhc2dab	ENSDARP00000137499	ENSDARP00000100252	Si:dkey-33b17.3.	Novel protein similar to vertebrate major histocompatibility complex class II DAB gene (Mhc2dab).	0.560
ENSDARP00000137499	zgc:103700	ENSDARP00000137499	ENSDARP00000154033	Si:dkey-33b17.3.	Zgc:103700.	0.555
ENSDARP00000140023	ENSDARP00000137499	ENSDARP00000140023	ENSDARP00000137499	Si:zfos-2070c2.3.	Si:dkey-33b17.3.	0.550
ENSDARP00000140023	ENSDARP00000143185	ENSDARP00000140023	ENSDARP00000143185	Si:zfos-2070c2.3.	Si:ch73-158p21.3.	0.560
ENSDARP00000140023	ENSDARP00000151819	ENSDARP00000140023	ENSDARP00000151819	Si:zfos-2070c2.3.	Ig-like domain-containing protein.	0.724
ENSDARP00000140023	F1QNN0_DANRE	ENSDARP00000140023	ENSDARP00000100115	Si:zfos-2070c2.3.	Si:zfos-367g9.1.	0.780
ENSDARP00000140023	F1R0K2_DANRE	ENSDARP00000140023	ENSDARP00000093621	Si:zfos-2070c2.3.	Si:zfos-2070c2.1.	0.681
ENSDARP00000140023	M9MM93_DANRE	ENSDARP00000140023	ENSDARP00000010619	Si:zfos-2070c2.3.	Si:ch73-211l2.3.	0.794
ENSDARP00000140023	dZ48C11.3-001	ENSDARP00000140023	ENSDARP00000136215	Si:zfos-2070c2.3.	Novel protein similar to MHC class II alpha chain.	0.677
ENSDARP00000140023	mhc2a	ENSDARP00000140023	ENSDARP00000048447	Si:zfos-2070c2.3.	Major histocompatibility complex class II integral membrane alpha chain gene.	0.683
ENSDARP00000140023	mhc2bl	ENSDARP00000140023	ENSDARP00000088705	Si:zfos-2070c2.3.	MHC class II beta chain-like.	0.550

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