STRINGSTRING
hoxb5b hoxb5b cdx1a cdx1a en1b en1b hoxc10a hoxc10a evx1 evx1 nkx6.2 nkx6.2 msx2b msx2b hoxa9a hoxa9a hoxa3a hoxa3a barhl2 barhl2 hhex hhex hoxa1a hoxa1a hoxa5a hoxa5a hoxc12b hoxc12b msx2a msx2a hoxa11a hoxa11a LOC100008066 LOC100008066 nkx2.2b nkx2.2b vent vent hoxc3a hoxc3a hmx3b hmx3b dlx4a dlx4a hoxb1b hoxb1b hoxc5a hoxc5a hoxd3a hoxd3a barx2 barx2 hoxb2a hoxb2a hmx2 hmx2 hoxc6a hoxc6a nkx3.3 nkx3.3 hoxc9a hoxc9a dlx2a dlx2a hoxb1a hoxb1a dlx5a dlx5a mnx2b mnx2b hoxb10a hoxb10a cdx4 cdx4 dlx4b dlx4b meox1 meox1 gbx1 gbx1 hmx3a hmx3a hoxc12a hoxc12a hoxc11a hoxc11a hoxc8a hoxc8a hoxc4a hoxc4a hoxc1a hoxc1a dlx6a dlx6a bsx bsx meox2b meox2b nkx1.2la nkx1.2la nkx6.3 nkx6.3 hoxd4a hoxd4a hoxd9a hoxd9a hoxd11a hoxd11a hoxd12a hoxd12a evx2 evx2 hoxd10a hoxd10a hoxa9b hoxa9b hoxb3a hoxb3a hoxb7a hoxb7a eve1 eve1 cdx1b cdx1b hoxb8b hoxb8b gsx2 gsx2 mnx2a mnx2a meox2a meox2a emx1 emx1 nkx2.3 nkx2.3 en2b en2b nkx3-2 nkx3-2 mnx1 mnx1 gsx1 gsx1 barhl1a barhl1a hoxa10b hoxa10b hoxb8a hoxb8a pnx pnx en2a en2a msx3 msx3 dbx1a dbx1a en1a en1a hoxa2b hoxa2b dlx3b dlx3b hoxb9a hoxb9a msx1b msx1b barx1 barx1 dbx1b dbx1b dlx1a dlx1a hmx4 hmx4 hoxb6b hoxb6b tlx2 tlx2 hoxb4a hoxb4a dlx2b dlx2b hoxa11b hoxa11b gbx2 gbx2 nkx2.7 nkx2.7 hoxb5a hoxb5a tlx1 tlx1 hoxb6a hoxb6a nkx2.2a nkx2.2a hoxc11b hoxc11b hoxc6b hoxc6b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hoxb5bHomeobox protein Hox-B5b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (276 aa)
cdx1aHomeodomain protein Cdx1a. (228 aa)
en1bHomeobox protein engrailed-like. (274 aa)
hoxc10aHomeobox C10a. (337 aa)
evx1Even-skipped homeobox 1. (377 aa)
nkx6.2NK6 homeobox 2. (278 aa)
msx2bHomeobox protein MSH-D; Involved in the development of the inner ear; Belongs to the Msh homeobox family. (241 aa)
hoxa9aHomeobox protein Hox-A9a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (250 aa)
hoxa3aHomeobox protein Hox-A3a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (410 aa)
barhl2BarH-class homeodomain transcription factor. (364 aa)
hhexHematopoietically-expressed homeobox protein hhex; Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor. Regulates the differentiation of both endothelial and blood cells. Plays a role in embryonic dorsoventral patterning by regulating bmp expression. May establish anterior identity. Functions in the embryo to regulate liver development. Functions extraembryonically to generate organ chirality. (177 aa)
hoxa1aHomeobox protein Hox-A1a; Sequence-specific transcription factor. Part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis (By similarity). (329 aa)
hoxa5aHomeobox protein Hox-A5a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (265 aa)
hoxc12bHomeobox protein Hox-C12b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (283 aa)
msx2aHomeobox protein MSH-A; Probable morphogenetic role; Belongs to the Msh homeobox family. (257 aa)
hoxa11aHomeobox protein Hox-A11a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (284 aa)
LOC100008066Homeobox domain-containing protein. (251 aa)
nkx2.2bNK2 transcription factor related 2b. (237 aa)
ventVentral-expressed homeobox. (170 aa)
hoxc3aHomeobox protein Hox-C3a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (257 aa)
hmx3bH6 family homeobox 3b. (196 aa)
dlx4aHomeobox protein Dlx4a. (250 aa)
hoxb1bHomeobox protein Hox-B1b; Sequence-specific transcription factor. Part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures. Seems to act in the maintenance and/or generation of hindbrain segments; Belongs to the Antp homeobox family. Labial subfamily. (229 aa)
hoxc5aHomeobox protein Hox-C5a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (213 aa)
hoxd3aHomeobox protein Hox-D3a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (396 aa)
barx2BARX homeobox 2. (268 aa)
hoxb2aHomeobox protein Hox-B2a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Plays an important role in the patterning of hindbrain and pharyngeal arches. (409 aa)
hmx2H6 family homeobox 2. (269 aa)
hoxc6aHomeobox protein Hox-C6a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (208 aa)
nkx3.3NK3 homeobox 3. (240 aa)
hoxc9aHomeobox protein Hox-C9a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (270 aa)
dlx2aHomeobox protein Dlx2a; Involved in the development of the inner ear; Belongs to the distal-less homeobox family. (274 aa)
hoxb1aHomeobox protein Hox-B1a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (316 aa)
dlx5aHomeobox protein Dlx5a; Belongs to the distal-less homeobox family. (282 aa)
mnx2bMotor neuron and pancreas homeobox 2b. (328 aa)
hoxb10aHomeobox protein Hox-B10a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (214 aa)
cdx4Caudal type homeo box transcription factor 4. (270 aa)
dlx4bHomeobox protein Dlx4b; During larvae development, may be important for neurocranium morphogenesis. (254 aa)
meox1Homeobox protein MOX-1; Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints. Binds specifically to the promoter of target genes and regulates their expression. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome. Acts by med [...] (253 aa)
gbx1Gastrulation brain homeobox 1. (316 aa)
hmx3aHomeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence (By similarity). Belongs to the HMX homeobox family. (297 aa)
hoxc12aHomeo box C12a. (274 aa)
hoxc11aHomeobox protein Hox-C11a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (306 aa)
hoxc8aHomeobox protein Hox-C8a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (250 aa)
hoxc4aHomeobox protein Hox-C4a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (268 aa)
hoxc1aHomeobox protein Hox-C1a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (302 aa)
dlx6aHomeobox protein Dlx6a. (247 aa)
bsxBrain-specific homeobox protein homolog; DNA binding protein that function as transcriptional activator. May play a role in the determination and function of cell types in the brain; Belongs to the distal-less homeobox family. (227 aa)
meox2bMesenchyme homeobox 2b. (289 aa)
nkx1.2laNK1 transcription factor-related 2-like,a. (270 aa)
nkx6.3NK6 homeobox 3. (272 aa)
hoxd4aHomeobox protein Hox-D4a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (256 aa)
hoxd9aHomeobox protein Hox-D9a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (262 aa)
hoxd11aHomeobox protein Hox-D11a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (276 aa)
hoxd12aHomeobox protein Hox-D12a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (277 aa)
evx2Even-skipped homeobox 2. (418 aa)
hoxd10aHomeobox protein Hox-D10a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (332 aa)
hoxa9bHomeobox protein Hox-A9b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (253 aa)
hoxb3aHomeobox protein Hox-B3a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (417 aa)
hoxb7aHomeobox protein Hox-B7a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (227 aa)
eve1Even-skipped-like1. (224 aa)
cdx1bCaudal type homeodomain protein. (255 aa)
hoxb8bHomeobox protein Hox-B8b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (247 aa)
gsx2GS homeobox 2. (242 aa)
mnx2aMotor neuron and pancreas homeobox 2a. (309 aa)
meox2aMesenchyme homeobox 2a. (302 aa)
emx1Homeobox protein EMX1; May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system; Belongs to the EMX homeobox family. (231 aa)
nkx2.3NK2 transcription factor related 3. (321 aa)
en2bHomeobox protein engrailed-2b. (261 aa)
nkx3-2Bagpipe homeobox transcription factor Bapx1. (245 aa)
mnx1Motor neuron and pancreas homeobox 1. (311 aa)
gsx1Genetic screen homeobox 1 protein. (243 aa)
barhl1aBarH-class homeodomain transcription factor 3. (299 aa)
hoxa10bHomeobox protein Hox-A10b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (330 aa)
hoxb8aHomeobox protein Hox-B8a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (245 aa)
pnxHomeobox protein pnx; Transcriptional repressor. Activity as a repressor is enhanced by binding to the corepressor tle3a. (182 aa)
en2aHomeobox protein engrailed-2a. (265 aa)
msx3Homeobox protein MSH-C; Involved in the development of the inner ear; Belongs to the Msh homeobox family. (273 aa)
dbx1aHomeobox protein DBX1-A; Belongs to the H2.0 homeobox family. (314 aa)
en1aHomeobox protein engrailed-1a. (231 aa)
hoxa2bHomeobox protein Hox-A2b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (363 aa)
dlx3bHomeobox protein Dlx3b; Involved in the development of the inner ear; Belongs to the distal-less homeobox family. (269 aa)
hoxb9aHomeobox protein Hox-B9a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (249 aa)
msx1bHomeobox protein MSH-B; Probable morphogenetic role; Belongs to the Msh homeobox family. (257 aa)
barx1Homeobox protein BarH-like 1; Transcription factor, is involved in craniofacial development, and in stomach organogenesis; Belongs to the BAR homeobox family. (248 aa)
dbx1bHomeobox protein DBX1-B; Belongs to the H2.0 homeobox family. (322 aa)
dlx1aHomeobox protein Dlx1a. (252 aa)
hmx4H6 family homeobox 4. (238 aa)
hoxb6bHomeobox protein Hox-B6b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (224 aa)
tlx2T cell leukemia homeobox 2. (301 aa)
hoxb4aHomeobox protein Hox-B4a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (246 aa)
dlx2bHomeobox protein Dlx2b. (276 aa)
hoxa11bHomeobox protein Hox-A11b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (283 aa)
gbx2Gastrulation brain homeo box 2. (342 aa)
nkx2.7NK2 transcription factor-related 7. (269 aa)
hoxb5aHomeobox protein Hox-B5a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (275 aa)
tlx1T-cell leukemia, homeobox 1. (301 aa)
hoxb6aHomeobox protein Hox-B6a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (228 aa)
nkx2.2aHomeobox protein Nkx-2.2a; Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas (By similarity). May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter (By similarity). (273 aa)
hoxc11bHomeobox C11b. (306 aa)
hoxc6bHomeobox protein Hox-C6b; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. (228 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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