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nhp2 nhp2 gadd45ab gadd45ab mrm3a mrm3a mrm3b mrm3b gadd45bb gadd45bb gadd45gb.1 gadd45gb.1 rpl7a rpl7a gadd45ga gadd45ga snu13a snu13a pelo pelo etf1b etf1b gadd45aa gadd45aa rpp38 rpp38 rps12 rps12 rpl30 rpl30 gadd45ba gadd45ba snu13b snu13b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
nhp2H/ACA ribonucleoprotein complex subunit 2-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity). (150 aa)
gadd45abGrowth arrest and DNA-damage-inducible, alpha, b. (156 aa)
mrm3arRNA methyltransferase 3A, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1485 (Gm1485) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. (443 aa)
mrm3brRNA methyltransferase 3B, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1485 (Gm1485) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. (449 aa)
gadd45bbGrowth arrest and DNA-damage-inducible, beta like. (158 aa)
gadd45gb.1Growth arrest and DNA-damage-inducible, gamma b, tandem duplicate 1. (155 aa)
rpl7aRibosomal protein L7a. (266 aa)
gadd45gaGrowth arrest and DNA-damage-inducible, gamma a. (159 aa)
snu13aRibonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
peloProtein pelota homolog; Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity (Potential). Belongs to the eukaryotic release factor 1 family. Pelota subfamily. (385 aa)
etf1bEukaryotic translation termination factor 1b. (442 aa)
gadd45aaGrowth arrest and DNA-damage-inducible, alpha, a. (157 aa)
rpp38Ribonuclease P/MRP 38 subunit. (265 aa)
rps1240S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
rpl30Ribosomal protein L30. (117 aa)
gadd45baGrowth arrest and DNA-damage-inducible, beta a. (159 aa)
snu13bRibonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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