node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC799279 | myd88 | ENSDARP00000144331 | ENSDARP00000020711 | Uncharacterized protein. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | 0.968 |
LOC799279 | zmp:0000000936 | ENSDARP00000144331 | ENSDARP00000105440 | Uncharacterized protein. | Zmp:0000000936. | 0.900 |
myd88 | LOC799279 | ENSDARP00000020711 | ENSDARP00000144331 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Uncharacterized protein. | 0.968 |
myd88 | sarm1 | ENSDARP00000020711 | ENSDARP00000014434 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | NAD(+) hydrolase SARM1; NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (By similarity). Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (By similarity). Wallerian degeneration is triggerred by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADP [...] | 0.891 |
myd88 | sigirr | ENSDARP00000020711 | ENSDARP00000084113 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain. | 0.726 |
myd88 | ticam1 | ENSDARP00000020711 | ENSDARP00000130000 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Toll-like receptor adaptor molecule 1. | 0.921 |
myd88 | tlr18 | ENSDARP00000020711 | ENSDARP00000124565 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Toll-like receptor 18. | 0.958 |
myd88 | tlr20.2 | ENSDARP00000020711 | ENSDARP00000108970 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Toll-like receptor 20, tandem duplicate 2. | 0.607 |
myd88 | tlr21 | ENSDARP00000020711 | ENSDARP00000098992 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Toll-like receptor 21. | 0.870 |
myd88 | tlr22 | ENSDARP00000020711 | ENSDARP00000152566 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Toll-like receptor 22; Belongs to the Toll-like receptor family. | 0.813 |
myd88 | tlr4al | ENSDARP00000020711 | ENSDARP00000098602 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Toll-like receptor 4a, like. | 0.997 |
myd88 | tlr4bb | ENSDARP00000020711 | ENSDARP00000028819 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Toll-like receptor 4b, duplicate b. | 0.998 |
myd88 | tlr5a | ENSDARP00000020711 | ENSDARP00000124209 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Toll-like receptor 5a; Belongs to the Toll-like receptor family. | 0.989 |
myd88 | tlr5b | ENSDARP00000020711 | ENSDARP00000124387 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Toll-like receptor 5b; Belongs to the Toll-like receptor family. | 0.989 |
myd88 | zmp:0000000936 | ENSDARP00000020711 | ENSDARP00000105440 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | Zmp:0000000936. | 0.968 |
sarm1 | myd88 | ENSDARP00000014434 | ENSDARP00000020711 | NAD(+) hydrolase SARM1; NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (By similarity). Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (By similarity). Wallerian degeneration is triggerred by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADP [...] | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | 0.891 |
sarm1 | ticam1 | ENSDARP00000014434 | ENSDARP00000130000 | NAD(+) hydrolase SARM1; NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (By similarity). Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (By similarity). Wallerian degeneration is triggerred by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADP [...] | Toll-like receptor adaptor molecule 1. | 0.664 |
sarm1 | tlr21 | ENSDARP00000014434 | ENSDARP00000098992 | NAD(+) hydrolase SARM1; NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (By similarity). Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway by promoting Wallerian degeneration, an injury-induced form of programmed subcellular death which involves degeneration of an axon distal to the injury site (By similarity). Wallerian degeneration is triggerred by NAD(+) depletion: in response to injury, SARM1 is activated and catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR), cyclic ADP [...] | Toll-like receptor 21. | 0.402 |
sigirr | myd88 | ENSDARP00000084113 | ENSDARP00000020711 | Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and Il-1 receptor signaling pathway in the innate immune response. | 0.726 |
sigirr | tlr5a | ENSDARP00000084113 | ENSDARP00000124209 | Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain. | Toll-like receptor 5a; Belongs to the Toll-like receptor family. | 0.420 |