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scn5lab scn5lab cacna1da cacna1da trpc3 trpc3 cacna1db-3 cacna1db-3 MCOLN3 MCOLN3 ENSDARP00000146052 ENSDARP00000146052 cacna1aa cacna1aa pkd1a pkd1a cacna1fb cacna1fb F1RD98_DANRE F1RD98_DANRE cacna1ba cacna1ba trpc2b trpc2b cacna1sb cacna1sb tpte tpte mcoln1b mcoln1b cacna1bb cacna1bb cacna1e cacna1e trpc6b trpc6b scn4ab scn4ab cacna1sa cacna1sa mcoln3a mcoln3a trpc6a trpc6a cacna1g cacna1g scn12aa scn12aa trpc7a trpc7a cacna1c cacna1c mcoln1a mcoln1a cacna1eb cacna1eb cacna1ia cacna1ia cacna1fa cacna1fa cacna1ib cacna1ib cacna1ha cacna1ha trpc2a trpc2a cacna1ab cacna1ab scn1laa scn1laa cacna1hb cacna1hb
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
scn5labSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1954 aa)
cacna1daVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2082 aa)
trpc3Transient receptor potential cation channel, subfamily C, member 3; Belongs to the transient receptor (TC 1.A.4) family. (902 aa)
cacna1db-3Calcium channel, voltage-dependent, L type, alpha 1D subunit, b. (207 aa)
MCOLN3Mucolipin 3. (595 aa)
ENSDARP00000146052Uncharacterized protein. (278 aa)
cacna1aaCalcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a. (2265 aa)
pkd1aPolycystic kidney disease 1a. (4346 aa)
cacna1fbVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2065 aa)
F1RD98_DANRESi:ch73-193i2.2. (803 aa)
cacna1baVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2312 aa)
trpc2bTransient receptor potential cation channel subfamily C member 2b; Belongs to the transient receptor (TC 1.A.4) family. (1139 aa)
cacna1sbVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1847 aa)
tpteTransmembrane phosphatase with tensin homology. (511 aa)
mcoln1bMucolipin 1.2. (565 aa)
cacna1bbVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2314 aa)
cacna1eCalcium channel, voltage-dependent, R type, alpha 1E subunit a. (1793 aa)
trpc6bTransient receptor potential cation channel, subfamily C, member 6b. (817 aa)
scn4abSodium channel protein type 4 subunit alpha B; Pore-forming subunit of a voltage-gated sodium channel complex through which Na(+) ions pass in accordance with their electrochemical gradient. Alternates between resting, activated and inactivated states. Required for normal muscle fiber excitability, normal muscle contraction and relaxation cycles. (1835 aa)
cacna1saVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1777 aa)
mcoln3aMucolipin 3a. (541 aa)
trpc6aTransient receptor potential cation channel, subfamily C, member 6a; Belongs to the transient receptor (TC 1.A.4) family. (874 aa)
cacna1gVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2239 aa)
scn12aaSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1932 aa)
trpc7aTransient receptor potential cation channel, subfamily C, member 7a; Belongs to the transient receptor (TC 1.A.4) family. (842 aa)
cacna1cVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2196 aa)
mcoln1aMucolipin 1a. (581 aa)
cacna1ebCalcium channel, voltage-dependent, R type, alpha 1E subunit b. (2164 aa)
cacna1iaCalcium voltage-gated channel subunit alpha1 Ia. (2188 aa)
cacna1faVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (659 aa)
cacna1ibCalcium voltage-gated channel subunit alpha1 Ib. (953 aa)
cacna1haVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2173 aa)
trpc2aTransient receptor potential cation channel subfamily C member 2a. (798 aa)
cacna1abCalcium channel, voltage-dependent, P/Q type, alpha 1A subunit, b. (2319 aa)
scn1laaSodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1955 aa)
cacna1hbCalcium channel, voltage-dependent, T type, alpha 1H subunit b. (1681 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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