STRINGSTRING
birc5a birc5a MGC174155 MGC174155 ccna2 ccna2 tnnt1 tnnt1 tpma tpma ccnd1 ccnd1 ctnnb1 ctnnb1 calr3b calr3b mibp2 mibp2 calr3a calr3a zgc:174153 zgc:174153 rpl31 rpl31 E9QBE2_DANRE E9QBE2_DANRE actb2 actb2 birc5b birc5b aars1 aars1 rpl17 rpl17 ctslb ctslb mef2aa mef2aa mef2d mef2d aars2 aars2 E7F8Y7_DANRE E7F8Y7_DANRE myf5 myf5 myhz2 myhz2 ctsla ctsla myhz1.1 myhz1.1 foxc1a foxc1a prim1 prim1 si:dkey-26g8.5 si:dkey-26g8.5 sgpl1 sgpl1 zgc:174855 zgc:174855 mcl1a mcl1a zgc:174154 zgc:174154 lectin lectin mespaa mespaa her7 her7 myog myog cp cp mylz3 mylz3 her6 her6 ccna1 ccna1 ctsl.1 ctsl.1 her1 her1 lmnl3 lmnl3 tnnt2c tnnt2c rps10 rps10 rps3a rps3a ccnb2 ccnb2 rps12 rps12 cts12 cts12 ccnb1 ccnb1 mylpfa mylpfa her9 her9 her4.1 her4.1 mef2ca mef2ca zp2.1 zp2.1 rps24 rps24 calr calr elk4 elk4 tnnt3a tnnt3a vsx1 vsx1 tnnc2 tnnc2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
birc5aBaculoviral IAP repeat-containing 5a. (190 aa)
MGC174155Cathepsin Lb; Belongs to the peptidase C1 family. (336 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (454 aa)
tnnt1Troponin T type 1 (skeletal, slow). (342 aa)
tpmaTropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family. (284 aa)
ccnd1G1/S-specific cyclin-D1; May play a role in transcriptional regulation (By similarity). Essential for the control of the cell cycle at the G1/S (start) transition. (291 aa)
ctnnb1Catenin beta-1; Key downstream component of the canonical Wnt signaling pathway (By similarity). In the absence of Wnt, forms a complex with axin1, axin2, apc, csnk1a1 and gsk3b that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of ctnnb1 and its subsequent degradation by the proteasome (By similarity). In the presence of Wnt ligand, ctnnb1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes (By similarity). Plays a key role in dorso [...] (789 aa)
calr3bCalreticulin. (417 aa)
mibp2Muscle-specific beta 1 integrin-binding protein 2. (203 aa)
calr3aCalreticulin. (418 aa)
zgc:174153Zgc:174153; Belongs to the peptidase C1 family. (336 aa)
rpl31Ribosomal protein L31. (123 aa)
E9QBE2_DANRESi:dkey-239j18.2; Belongs to the peptidase C1 family. (335 aa)
actb2Actin, cytoplasmic 2, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
birc5bBaculoviral IAP repeat-containing 5b. (144 aa)
aars1Alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. (991 aa)
rpl17Ribosomal protein L17; Belongs to the universal ribosomal protein uL22 family. (184 aa)
ctslbCathepsin Lb; Belongs to the peptidase C1 family. (352 aa)
mef2aaMyocyte enhancer factor 2aa. (458 aa)
mef2dMyocyte enhancer factor 2d. (529 aa)
aars2Alanyl-tRNA synthetase 2, mitochondrial (putative). (997 aa)
E7F8Y7_DANRESi:dkey-239j18.3; Belongs to the peptidase C1 family. (336 aa)
myf5Myogenic factor. (237 aa)
myhz2Myosin, heavy polypeptide 2, fast muscle-specific; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1935 aa)
ctslaCathepsin La; Belongs to the peptidase C1 family. (337 aa)
myhz1.1Myosin, heavy polypeptide 1.1, skeletal muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
foxc1aForkhead box C1-A; DNA-binding transcriptional factor that plays a role in a broad range of cellular and developmental processes such as eye, bones, cardiovascular, kidney and skin development. Acts either as a transcriptional activator or repressor. Binds to the consensus binding site 5'-[G/C][A/T]AAA[T/C]AA[A/C]-3' in promoter of target genes. Upon DNA-binding, promotes DNA bending. Required for cell viability and resistance to oxidative stress in the eye. Promotes cell growth inhibition by stopping the cell cycle in the G1 phase through TGFB1- mediated signals. Involved in epithelia [...] (476 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (425 aa)
si:dkey-26g8.5MGC174857 protein; Belongs to the peptidase C1 family. (335 aa)
sgpl1Sphingosine-1-phosphate lyase 1. (572 aa)
zgc:174855Im:6910535 protein; Belongs to the peptidase C1 family. (335 aa)
mcl1aMCL1 apoptosis regulator, BCL2 family member a. (255 aa)
zgc:174154Im:6910535; Belongs to the peptidase C1 family. (335 aa)
lectinLectin. (152 aa)
mespaaMesp-related bHLH transcription factor mesp-a. (223 aa)
her7Hairy and enhancer of split-related-7. (206 aa)
myogMyogenin. (256 aa)
cpCeruloplasmin; Belongs to the multicopper oxidase family. (1087 aa)
mylz3Fast skeletal muscle myosin light polypeptide 3. (151 aa)
her6Hairy-related 6. (270 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (391 aa)
ctsl.1Cathepsin L.1; Belongs to the peptidase C1 family. (334 aa)
her1Hairy-related 1. (328 aa)
lmnl3Lamin L3; Belongs to the intermediate filament family. (584 aa)
tnnt2cTroponin T1, skeletal, slow. (290 aa)
rps10Ribosomal protein S10. (166 aa)
rps3a40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (267 aa)
ccnb2Cyclin B2; Belongs to the cyclin family. (386 aa)
rps1240S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
cts12Cathepsin 12; Belongs to the peptidase C1 family. (349 aa)
ccnb1Cyclin B1; Belongs to the cyclin family. (397 aa)
mylpfaMyosin light chain, phosphorylatable, fast skeletal muscle a. (169 aa)
her9BHLH-WRPW transcription factor. (291 aa)
her4.1Hairy-related 4, tandem duplicate 1. (152 aa)
mef2caMyocyte enhancer factor 2ca. (465 aa)
zp2.1Zona pellucida glycoprotein 2, tandem duplicate 1. (431 aa)
rps2440S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (132 aa)
calrCalreticulin. (417 aa)
elk4ETS transcription factor ELK4. (443 aa)
tnnt3aTroponin T type 3a (skeletal, fast). (230 aa)
vsx1Visual system homeobox 1; May be involved in maintenance as well as cellular differentiation of retinal interneurons, such as bipolar cells. May play a role in establishing interneuronal cell classes in nonsensory as well as sensory systems; Belongs to the paired homeobox family. (340 aa)
tnnc2Fast skeletal muscle troponin C. (160 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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