STRINGSTRING
tgfb1a tgfb1a arntl1a arntl1a tnfb tnfb tgfb3 tgfb3 gsk3ba gsk3ba fabp3 fabp3 nos2b nos2b cd36 cd36 ins ins apoeb apoeb mstnb mstnb tgfb5 tgfb5 nr1d1 nr1d1 nos2a nos2a loxa loxa insb insb tgfb1b tgfb1b nos1 nos1 pparg pparg
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tgfb1aTransforming growth factor beta; Belongs to the TGF-beta family. (377 aa)
arntl1aAryl hydrocarbon receptor nuclear translocator-like 1a. (626 aa)
tnfbTumor necrosis factor b (TNF superfamily, member 2). (242 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (410 aa)
gsk3baGlycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily. (421 aa)
fabp3Fatty acid-binding protein 3, muscle and heart; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
nos2bNitric oxide synthase; Produces nitric oxide (NO). (1077 aa)
cd36CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (465 aa)
insInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
apoebApolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family. (281 aa)
mstnbGrowth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth. May down-regulate muscle-specific transcription factors such as myod and myog. (374 aa)
tgfb5Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
nr1d1Nuclear receptor subfamily 1, group d, member 1. (637 aa)
nos2aNitric oxide synthase; Produces nitric oxide (NO). (1079 aa)
loxaLysyl oxidase a. (408 aa)
insbInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (159 aa)
tgfb1bTransforming growth factor beta; Belongs to the TGF-beta family. (379 aa)
nos1Nitric oxide synthase; Produces nitric oxide (NO). (1431 aa)
ppargPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (116 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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