node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
col1a2 | mylpfa | ENSDARP00000118091 | ENSDARP00000069948 | Collagen, type I, alpha 2. | Myosin light chain, phosphorylatable, fast skeletal muscle a. | 0.440 |
dlx2a | fgf8a | ENSDARP00000103004 | ENSDARP00000018653 | Homeobox protein Dlx2a; Involved in the development of the inner ear; Belongs to the distal-less homeobox family. | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | 0.731 |
dlx2a | shha | ENSDARP00000103004 | ENSDARP00000125090 | Homeobox protein Dlx2a; Involved in the development of the inner ear; Belongs to the distal-less homeobox family. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.784 |
dlx2a | sox10 | ENSDARP00000103004 | ENSDARP00000100237 | Homeobox protein Dlx2a; Involved in the development of the inner ear; Belongs to the distal-less homeobox family. | HMG-box transcription factor Sox10. | 0.846 |
fgf8a | dlx2a | ENSDARP00000018653 | ENSDARP00000103004 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Homeobox protein Dlx2a; Involved in the development of the inner ear; Belongs to the distal-less homeobox family. | 0.731 |
fgf8a | myod1 | ENSDARP00000018653 | ENSDARP00000009713 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Myoblast determination protein 1 homolog; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. | 0.576 |
fgf8a | pax3a | ENSDARP00000018653 | ENSDARP00000037761 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Transcription factor PAX3. | 0.661 |
fgf8a | pxdn | ENSDARP00000018653 | ENSDARP00000131814 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Peroxidasin. | 0.430 |
fgf8a | shha | ENSDARP00000018653 | ENSDARP00000125090 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.960 |
fgf8a | smo | ENSDARP00000018653 | ENSDARP00000013486 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.640 |
fgf8a | sox10 | ENSDARP00000018653 | ENSDARP00000100237 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration (By similarity). Required for Kupffer's vesicle ciliogenesis. | HMG-box transcription factor Sox10. | 0.717 |
myf5 | myf6 | ENSDARP00000109289 | ENSDARP00000040265 | Myogenic factor. | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | 0.718 |
myf5 | mylpfa | ENSDARP00000109289 | ENSDARP00000069948 | Myogenic factor. | Myosin light chain, phosphorylatable, fast skeletal muscle a. | 0.841 |
myf5 | pax3a | ENSDARP00000109289 | ENSDARP00000037761 | Myogenic factor. | Transcription factor PAX3. | 0.958 |
myf5 | prdm1a | ENSDARP00000109289 | ENSDARP00000004889 | Myogenic factor. | PR domain-containing 1a, with ZNF domain. | 0.484 |
myf5 | shha | ENSDARP00000109289 | ENSDARP00000125090 | Myogenic factor. | Sonic hedgehog protein A N-product; Sonic hedgehog protein: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). | 0.575 |
myf6 | myf5 | ENSDARP00000040265 | ENSDARP00000109289 | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | Myogenic factor. | 0.718 |
myf6 | mylpfa | ENSDARP00000040265 | ENSDARP00000069948 | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | Myosin light chain, phosphorylatable, fast skeletal muscle a. | 0.663 |
myf6 | myod1 | ENSDARP00000040265 | ENSDARP00000009713 | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | Myoblast determination protein 1 homolog; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. | 0.677 |
myf6 | pax3a | ENSDARP00000040265 | ENSDARP00000037761 | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein (By similarity). | Transcription factor PAX3. | 0.882 |