STRINGSTRING
en2a en2a actn3b actn3b prdm1a prdm1a mybpc1 mybpc1 myod1 myod1 myog myog hsp90aa1.1 hsp90aa1.1 hsp70l hsp70l pax3a pax3a acta1b acta1b mylpfa mylpfa srfa srfa mef2ca mef2ca tnnc2 tnnc2 myhz1.1 myhz1.1 ttn.1 ttn.1 hsp70.1 hsp70.1 mef2d mef2d mef2aa mef2aa pxdn pxdn smyhc1 smyhc1 tpma tpma
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
en2aHomeobox protein engrailed-2a. (265 aa)
actn3bActinin alpha 3b. (898 aa)
prdm1aPR domain-containing 1a, with ZNF domain. (776 aa)
mybpc1Myosin-binding protein C1. (1167 aa)
myod1Myoblast determination protein 1 homolog; May act as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. (275 aa)
myogMyogenin. (256 aa)
hsp90aa1.1Heat shock protein HSP 90-alpha 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a [...] (725 aa)
hsp70lNovel protein similar to heat shock cognate 70-kd protein; Belongs to the heat shock protein 70 family. (643 aa)
pax3aTranscription factor PAX3. (509 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
mylpfaMyosin light chain, phosphorylatable, fast skeletal muscle a. (169 aa)
srfaSerum response factor a. (539 aa)
mef2caMyocyte enhancer factor 2ca. (465 aa)
tnnc2Fast skeletal muscle troponin C. (160 aa)
myhz1.1Myosin, heavy polypeptide 1.1, skeletal muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
ttn.1Titin, tandem duplicate 1. (29152 aa)
hsp70.1Heat shock cognate 70-kd protein, tandem duplicate 1; Belongs to the heat shock protein 70 family. (643 aa)
mef2dMyocyte enhancer factor 2d. (529 aa)
mef2aaMyocyte enhancer factor 2aa. (458 aa)
pxdnPeroxidasin. (1460 aa)
smyhc1Slow myosin heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1938 aa)
tpmaTropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family. (284 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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