STRINGSTRING
cfl2 cfl2 actn3b actn3b prkacab prkacab plek2 plek2 ckmt1 ckmt1 casq1b casq1b gnaq gnaq casq2 casq2 prkacba prkacba ckbb ckbb flncb flncb gsna gsna tcap tcap nebl nebl ckma ckma atp2a2a atp2a2a atp2a1 atp2a1 capn1a capn1a flnca flnca scin scin gsnb gsnb ckmt2b ckmt2b acta1b acta1b ckmb ckmb trim54 trim54 cryaba cryaba obscna obscna ankrd2 ankrd2 F1Q9Z1_DANRE F1Q9Z1_DANRE srfa srfa E9QFN0_DANRE E9QFN0_DANRE and3 and3 scinlb scinlb prkacbb prkacbb ckmt2a ckmt2a src src capn1b capn1b rabif rabif zgc:55262 zgc:55262 nrap nrap tmod4 tmod4 flna flna Q5RHR2_DANRE Q5RHR2_DANRE flnb flnb neb neb nbr1a nbr1a obsl1a obsl1a E7FC63_DANRE E7FC63_DANRE plek plek ckba ckba casq1a casq1a prkacaa prkacaa nsmfb nsmfb csrp3 csrp3 scinla scinla capn3a capn3a obscnb obscnb tpma tpma Flnb Flnb Mypn Mypn
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cfl2Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
actn3bActinin alpha 3b. (898 aa)
prkacabProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (351 aa)
plek2Plek2 protein. (361 aa)
ckmt1Creatine kinase, mitochondrial 1; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
casq1bCalsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (454 aa)
gnaqGuanine nucleotide-binding protein (G protein), q polypeptide. (359 aa)
casq2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (409 aa)
prkacbaProtein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily. (395 aa)
ckbbBrain-subtype creatine kinase; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
flncbFilamin C, gamma b (actin-binding protein 280). (2773 aa)
gsnaGelsolin a. (729 aa)
tcapTitin-cap (telethonin). (179 aa)
neblNebulette. (276 aa)
ckmaCreatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
atp2a2aCalcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (996 aa)
atp2a1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1005 aa)
capn1aCalpain 1, (mu/I) large subunit a; Belongs to the peptidase C2 family. (704 aa)
flncaFilamin C, gamma a (actin-binding protein 280). (2719 aa)
scinScinderin. (733 aa)
gsnbGelsolin b. (728 aa)
ckmt2bCreatine kinase, mitochondrial 2b (sarcomeric); Belongs to the ATP:guanido phosphotransferase family. (413 aa)
acta1bActin alpha 1, skeletal muscle b. (377 aa)
ckmbCreatine kinase, muscle b; Belongs to the ATP:guanido phosphotransferase family. (380 aa)
trim54Tripartite motif-containing 54. (359 aa)
cryabaCrystallin, alpha B, a; Belongs to the small heat shock protein (HSP20) family. (168 aa)
obscnaObscurin, cytoskeletal calmodulin and titin-interacting RhoGEF a. (1992 aa)
ankrd2Ankyrin repeat domain 2 (stretch-responsive muscle). (296 aa)
F1Q9Z1_DANRESi:ch211-202f3.3; Belongs to the peptidase C2 family. (736 aa)
srfaSerum response factor a. (539 aa)
E9QFN0_DANRESi:dkeyp-50d11.2; Belongs to the peptidase C2 family. (704 aa)
and3Actinodin3. (295 aa)
scinlbScinderin-like b. (720 aa)
prkacbbProtein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
ckmt2aCreatine kinase, mitochondrial 2a (sarcomeric); Belongs to the ATP:guanido phosphotransferase family. (417 aa)
srcProto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy bet [...] (534 aa)
capn1bCalpain 1, (mu/I) large subunit b; Belongs to the peptidase C2 family. (700 aa)
rabifRAB-interacting factor. (132 aa)
zgc:55262Zgc:55262; Belongs to the peptidase C2 family. (704 aa)
nrapNebulin-related-anchoring protein. (1861 aa)
tmod4Tropomodulin 4 (Muscle). (343 aa)
flnaFilamin A, alpha (actin-binding protein 280). (2553 aa)
Q5RHR2_DANREAdenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1187 aa)
flnbFilamin B, beta (actin-binding protein 278). (2233 aa)
nebNebulin. (6177 aa)
nbr1aNBR1 autophagy cargo receptor a. (989 aa)
obsl1aObscurin-like cytoskeletal adaptor 1a. (2006 aa)
E7FC63_DANREAdenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1183 aa)
plekPleckstrin. (352 aa)
ckbaCreatine kinase, brain a; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
casq1aCalsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (553 aa)
prkacaaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (352 aa)
nsmfbNMDA receptor synaptonuclear signaling and neuronal migration factor; Stimulates outgrowth of olfactory axons and migration of hypophysiotropic gonadotropin-releasing hormone 3 (GnRH3) neurons. May couple NMDA-sensitive glutamate receptor signaling to the nucleus and trigger long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. (570 aa)
csrp3Cysteine and glycine-rich protein 3 (cardiac LIM protein). (193 aa)
scinlaScinderin-like a. (720 aa)
capn3aCalpain 3a, (p94); Belongs to the peptidase C2 family. (725 aa)
obscnbObscurin, cytoskeletal calmodulin and titin-interacting RhoGEF b. (1660 aa)
tpmaTropomyosin alpha-1 chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments; Belongs to the tropomyosin family. (284 aa)
FlnbUncharacterized protein. (157 aa)
MypnUncharacterized protein. (663 aa)
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.